Cobalt in PDB 1bmt: How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase

All present enzymatic activity of How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase:
2.1.1.13;

The structure of How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase, PDB code: 1bmt was solved by C.L.Drennan, S.Huang, J.T.Drummond, R.G.Matthews, M.L.Ludwig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	96.700, 55.300, 103.800, 90.00, 90.00, 90.00
R / Rfree (%)	17 / n/a

The binding sites of Cobalt atom in the How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase (pdb code 1bmt). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase, PDB code: 1bmt:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Co122 b:2.0 occ:1.00 CO A:COB122 0.0 2.0 1.0 N24 A:COB122 1.9 2.0 1.0 N21 A:COB122 1.9 2.0 1.0 C1A A:COB122 2.0 5.4 1.0 N22 A:COB122 2.0 7.4 1.0 N23 A:COB122 2.0 4.9 1.0 NE2 A:HIS759 2.2 13.0 1.0 C19 A:COB122 2.7 10.3 1.0 C1 A:COB122 2.7 8.9 1.0 C4 A:COB122 2.9 2.2 1.0 C16 A:COB122 2.9 3.1 1.0 C6 A:COB122 2.9 2.5 1.0 C9 A:COB122 2.9 3.6 1.0 C14 A:COB122 2.9 3.6 1.0 C11 A:COB122 3.0 4.5 1.0 CE1 A:HIS759 3.3 14.7 1.0 CD2 A:HIS759 3.3 12.6 1.0 C5 A:COB122 3.3 2.0 1.0 C10 A:COB122 3.3 2.0 1.0 C20 A:COB122 3.3 9.3 1.0 C15 A:COB122 3.3 4.3 1.0 C18 A:COB122 3.9 6.9 1.0 C2 A:COB122 4.1 6.3 1.0 C17 A:COB122 4.1 4.2 1.0 C7 A:COB122 4.1 6.4 1.0 C3 A:COB122 4.2 2.0 1.0 C8 A:COB122 4.2 6.6 1.0 C13 A:COB122 4.2 2.5 1.0 C12 A:COB122 4.3 5.9 1.0 ND1 A:HIS759 4.4 8.8 1.0 CG A:HIS759 4.4 9.0 1.0 C37 A:COB122 4.7 10.4 1.0 C26 A:COB122 4.7 3.5 1.0 C35 A:COB122 4.7 2.0 1.0 C48 A:COB122 4.8 2.0 1.0 C46 A:COB122 4.8 8.0 1.0 C41 A:COB122 4.9 5.6 1.0 C54 A:COB122 4.9 4.3 1.0

Cobalt binding site 2 out of 2 in the How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of How A Protein Binds B12: A 3.O Angstrom X-Ray Structure of the B12-Binding Domains of Methionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ B:Co122 b:9.9 occ:1.00 CO B:COB122 0.0 9.9 1.0 N21 B:COB122 1.8 3.4 1.0 N22 B:COB122 1.9 7.0 1.0 N24 B:COB122 1.9 6.8 1.0 N23 B:COB122 2.0 6.9 1.0 C1A B:COB122 2.1 8.1 1.0 NE2 B:HIS759 2.1 8.6 1.0 C1 B:COB122 2.7 9.6 1.0 C19 B:COB122 2.7 7.1 1.0 C4 B:COB122 2.8 9.4 1.0 C6 B:COB122 2.8 11.1 1.0 C9 B:COB122 2.9 6.3 1.0 C16 B:COB122 3.0 2.3 1.0 C14 B:COB122 3.0 6.4 1.0 C11 B:COB122 3.0 5.1 1.0 CE1 B:HIS759 3.1 12.4 1.0 C5 B:COB122 3.2 8.9 1.0 CD2 B:HIS759 3.3 3.1 1.0 C20 B:COB122 3.3 8.0 1.0 C10 B:COB122 3.4 4.4 1.0 C15 B:COB122 3.4 3.3 1.0 C18 B:COB122 3.9 6.2 1.0 C2 B:COB122 4.1 10.4 1.0 C7 B:COB122 4.1 12.0 1.0 C3 B:COB122 4.1 8.8 1.0 C17 B:COB122 4.2 5.8 1.0 C8 B:COB122 4.2 8.6 1.0 ND1 B:HIS759 4.3 2.0 1.0 C13 B:COB122 4.3 6.7 1.0 C12 B:COB122 4.4 3.4 1.0 CG B:HIS759 4.4 6.5 1.0 C26 B:COB122 4.7 15.8 1.0 C35 B:COB122 4.7 12.8 1.0 C37 B:COB122 4.7 12.9 1.0 C41 B:COB122 4.8 6.0 1.0 C48 B:COB122 4.8 8.0 1.0 C30 B:COB122 4.9 3.6 1.0 C53 B:COB122 5.0 7.3 1.0

C.L.Drennan, S.Huang, J.T.Drummond, R.G.Matthews, M.L.Lidwig. How A Protein Binds B12: A 3.0 A X-Ray Structure of B12-Binding Domains of Methionine Synthase. Science V. 266 1669 1994.
ISSN: ISSN 0036-8075
PubMed: 7992050