Cobalt in PDB 1bsj: Cobalt Deformylase Inhibitor Complex From E.Coli

All present enzymatic activity of Cobalt Deformylase Inhibitor Complex From E.Coli:
3.5.1.27;

The structure of Cobalt Deformylase Inhibitor Complex From E.Coli, PDB code: 1bsj was solved by B.Hao, W.Gong, P.T.Rajagopalan, Y.Hu, D.Pei, M.K.Chan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.00
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	99.080, 99.080, 111.040, 90.00, 90.00, 120.00
R / Rfree (%)	16.8 / 20.7

The binding sites of Cobalt atom in the Cobalt Deformylase Inhibitor Complex From E.Coli (pdb code 1bsj). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Cobalt Deformylase Inhibitor Complex From E.Coli, PDB code: 1bsj:

Cobalt binding site 1 out of 1 in the Cobalt Deformylase Inhibitor Complex From E.Coli


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Cobalt Deformylase Inhibitor Complex From E.Coli within 5.0Å range: probe atom residue distance (Å) B Occ A:Co169 b:18.7 occ:1.00 NE2 A:HIS132 2.1 20.0 1.0 NE2 A:HIS136 2.1 23.7 1.0 O3 A:MLN171 2.2 23.0 1.0 SG A:CYS90 2.4 23.3 1.0 CD2 A:HIS136 3.0 25.6 1.0 CD2 A:HIS132 3.0 15.6 1.0 CE1 A:HIS132 3.1 17.4 1.0 O4 A:MLN171 3.1 23.4 1.0 CE1 A:HIS136 3.2 20.8 1.0 P1 A:MLN171 3.3 19.0 1.0 O A:HOH183 3.3 26.6 1.0 CB A:CYS90 3.4 20.8 1.0 NE2 A:GLN50 3.6 24.2 1.0 CA A:CYS90 3.9 23.2 1.0 C5 A:MLN171 4.0 23.9 1.0 CD A:GLN50 4.0 25.3 1.0 O2 A:MLN171 4.1 21.4 1.0 OE1 A:GLN50 4.1 27.9 1.0 CG A:HIS136 4.2 23.3 1.0 CG A:HIS132 4.2 19.2 1.0 ND1 A:HIS132 4.2 17.3 1.0 ND1 A:HIS136 4.3 23.1 1.0 C7 A:MLN171 4.3 20.2 1.0 OE2 A:GLU133 4.4 18.7 1.0 O A:GLY89 4.5 17.5 1.0 O A:HOH172 4.5 20.1 1.0 N A:LEU91 4.6 21.6 1.0 C A:CYS90 4.7 22.1 1.0 OE1 A:GLU133 4.8 15.1 1.0 CD A:GLU133 5.0 17.3 1.0

B.Hao, W.Gong, P.T.Rajagopalan, Y.Zhou, D.Pei, M.K.Chan. Structural Basis For the Design of Antibiotics Targeting Peptide Deformylase. Biochemistry V. 38 4712 1999.
ISSN: ISSN 0006-2960
PubMed: 10200158
DOI: 10.1021/BI982594C