Cobalt in PDB 1l8x: Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion

All present enzymatic activity of Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion:
4.99.1.1;

The structure of Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion, PDB code: 1l8x was solved by T.Karlberg, D.Lecerof, M.Gora, G.Silvegren, R.Labbe-Bois, M.Hansson, S.Al-Karadaghi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	84.380, 96.660, 120.700, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 28.7

The binding sites of Cobalt atom in the Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion (pdb code 1l8x). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion, PDB code: 1l8x:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Co501 b:38.2 occ:0.71 NE2 A:HIS235 2.0 40.0 1.0 CE1 A:HIS235 2.8 39.5 1.0 CD2 A:HIS235 3.2 38.5 1.0 ND1 A:HIS235 4.0 37.4 1.0 CG A:HIS235 4.2 36.5 1.0 CB A:SER275 4.2 40.1 1.0 O A:SER275 4.2 44.2 1.0 OG A:SER275 5.0 42.7 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Ferrochelatase From the Yeast, Saccharomyces Cerevisiae, with Cobalt(II) As the Substrate Ion within 5.0Å range: probe atom residue distance (Å) B Occ B:Co502 b:42.2 occ:0.84 NE2 B:HIS235 1.9 42.5 1.0 CD2 B:HIS235 2.6 41.2 1.0 OE2 B:GLU314 2.8 66.7 1.0 CE1 B:HIS235 3.0 42.9 1.0 OG B:SER275 3.7 56.0 1.0 CG B:HIS235 3.7 39.4 1.0 ND1 B:HIS235 3.9 41.6 1.0 CD B:GLU314 4.0 66.0 1.0 CB B:SER275 4.5 54.8 1.0 OE1 B:GLU314 4.7 65.2 1.0 SD B:MET46 4.7 62.3 1.0

T.Karlberg, D.Lecerof, M.Gora, G.Silvegren, R.Labbe-Bois, M.Hansson, S.Al-Karadaghi. Metal Binding to Saccharomyces Cerevisiae Ferrochelatase Biochemistry V. 41 13499 2002.
ISSN: ISSN 0006-2960
PubMed: 12427010
DOI: 10.1021/BI0260785