Cobalt in PDB 1m5a: Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution

The structure of Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution, PDB code: 1m5a was solved by J.M.Nicholson, L.C.Perkins, F.C.Korber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.20
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	80.750, 80.750, 33.630, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Cobalt atom in the Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution (pdb code 1m5a). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution, PDB code: 1m5a:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Co301 b:2.0 occ:0.33 NE2 B:HIS10 2.1 7.2 1.0 O B:HOH308 2.3 17.9 1.0 CE1 B:HIS10 3.0 11.5 1.0 CD2 B:HIS10 3.1 8.6 1.0 ND1 B:HIS10 4.1 13.4 1.0 CG B:HIS10 4.1 14.0 1.0 O B:HOH336 4.4 23.2 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ D:Co302 b:2.0 occ:0.33 NE2 D:HIS10 2.2 10.4 1.0 O D:HOH315 2.3 17.0 1.0 CD2 D:HIS10 3.1 9.5 1.0 CE1 D:HIS10 3.1 9.7 1.0 O D:HOH338 3.5 58.2 1.0 O D:HOH324 4.0 38.0 1.0 CG D:HIS10 4.2 8.3 1.0 ND1 D:HIS10 4.3 10.1 1.0 O D:HOH317 4.5 25.0 1.0 O D:HOH312 4.8 55.0 1.0

J.M.Nicholson, L.C.Perkins, F.C.Korber. The High-Resolution Structure of Hexameric T6 Cobalt Insulin: A Possible Pathway For the T to R Transition. Recent Research Developments V. 3 1 2006IN Molecular Biology.