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Atomistry » Cobalt » PDB 1rrk-1vlx » 1t31 » |
Cobalt in PDB 1t31: A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of InflammationEnzymatic activity of A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
All present enzymatic activity of A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation:
3.4.21.39; Protein crystallography data
The structure of A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation, PDB code: 1t31
was solved by
L.De Garavilla,
M.N.Greco,
E.C.Giardino,
G.I.Wells,
B.J.Haertlein,
J.A.Kauffman,
T.W.Corcoran,
C.K.Derian,
A.J.Eckardt,
W.M.Abraham,
N.Sukumar,
Z.Chen,
A.O.Pineda,
F.S.Mathews,
E.Di Cera,
P.Andrade-Gordon,
B.P.Damiano,
B.E.Maryanoff,
P.J.B.Pereira,
Z.M.Wang,
H.Rubin,
R.Huber,
W.Bode,
N.M.Schechter,
S.Strobl,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Cobalt Binding Sites:
The binding sites of Cobalt atom in the A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
(pdb code 1t31). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation, PDB code: 1t31: Cobalt binding site 1 out of 1 in 1t31Go back to Cobalt Binding Sites List in 1t31
Cobalt binding site 1 out
of 1 in the A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
Mono view Stereo pair view
Reference:
L.De Garavilla,
M.N.Greco,
N.Sukumar,
Z.W.Chen,
A.O.Pineda,
F.S.Mathews,
E.Di Cera,
E.C.Giardino,
G.I.Wells,
B.J.Haertlein,
J.A.Kauffman,
T.W.Corcoran,
C.K.Derian,
A.J.Eckardt,
B.P.Damiano,
P.Andrade-Gordon,
B.E.Maryanoff.
A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase: Molecular Mechanisms and Anti-Inflammatory Activity in Vivo. J.Biol.Chem. V. 280 18001 2005.
Page generated: Sun Dec 13 10:36:11 2020
ISSN: ISSN 0021-9258 PubMed: 15741158 DOI: 10.1074/JBC.M501302200 |
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