Cobalt in PDB 1xeo: High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate

All present enzymatic activity of High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate:
3.5.1.88;

The structure of High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate, PDB code: 1xeo was solved by R.Jain, B.Hao, R.-P.Liu, M.K.Chan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 1.30
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	54.420, 54.420, 224.430, 90.00, 90.00, 120.00
R / Rfree (%)	20 / 21.5

The binding sites of Cobalt atom in the High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate (pdb code 1xeo). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate, PDB code: 1xeo:

Cobalt binding site 1 out of 1 in the High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of High Resolution Crystals Structure of Cobalt- Peptide Deformylase Bound to Formate within 5.0Å range: probe atom residue distance (Å) B Occ A:Co301 b:16.9 occ:1.00 NE2 A:HIS136 2.0 14.7 1.0 NE2 A:HIS132 2.0 14.9 1.0 O2 A:FMT401 2.3 22.7 1.0 SG A:CYS90 2.3 18.0 1.0 O1 A:FMT401 2.3 22.6 1.0 C A:FMT401 2.8 24.3 1.0 CE1 A:HIS136 3.0 15.8 1.0 CD2 A:HIS132 3.1 14.8 1.0 CE1 A:HIS132 3.1 14.8 1.0 CD2 A:HIS136 3.1 14.3 1.0 CB A:CYS90 3.3 16.5 1.0 NE2 A:GLN50 3.5 15.5 1.0 CA A:CYS90 3.7 17.4 1.0 O A:HOH432 3.7 18.1 1.0 CD A:GLN50 4.0 15.3 1.0 OE1 A:GLN50 4.0 16.5 1.0 ND1 A:HIS136 4.2 15.1 1.0 CG A:HIS132 4.2 14.5 1.0 ND1 A:HIS132 4.2 15.3 1.0 N A:LEU91 4.2 16.4 1.0 CG A:HIS136 4.2 13.9 1.0 C A:CYS90 4.4 16.7 1.0 O A:HOH405 4.6 16.2 1.0 O A:GLY89 4.6 19.4 1.0 OE1 A:GLU133 4.6 24.0 1.0 OE2 A:GLU133 4.7 25.1 1.0 O A:HOH579 4.8 37.3 1.0 N A:CYS90 5.0 17.2 1.0 N A:SER92 5.0 16.3 1.0

R.Jain, B.Hao, R.-P.Liu, M.K.Chan. Structures of E. Coli Peptide Deformylase Bound to Formate: Insight Into the Preference For FE2+ Over ZN2+ As the Active Site Metal J.Am.Chem.Soc. V. 127 4558 2005.
ISSN: ISSN 0002-7863
PubMed: 15796505
DOI: 10.1021/JA0503074