Cobalt in PDB 1zjc: Aminopeptidase S From S. Aureus

The structure of Aminopeptidase S From S. Aureus, PDB code: 1zjc was solved by S.G.Odintsov, I.Sabala, G.Bourenkov, V.Rybin, M.Bochtler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	70.181, 81.858, 152.885, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21.2

The binding sites of Cobalt atom in the Aminopeptidase S From S. Aureus (pdb code 1zjc). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 3 binding sites of Cobalt where determined in the Aminopeptidase S From S. Aureus, PDB code: 1zjc:
Jump to Cobalt binding site number: 1; 2; 3;

Cobalt binding site 1 out of 3 in the Aminopeptidase S From S. Aureus


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Aminopeptidase S From S. Aureus within 5.0Å range: probe atom residue distance (Å) B Occ A:Co501 b:24.4 occ:1.00 O A:HOH883 2.0 27.2 1.0 OE2 A:GLU319 2.0 19.8 1.0 OE1 A:GLU253 2.1 17.4 1.0 NE2 A:HIS348 2.2 16.6 1.0 OE2 A:GLU253 2.5 20.7 1.0 O A:HOH533 2.5 24.7 1.0 CD A:GLU253 2.6 17.2 1.0 CE1 A:HIS348 3.0 17.3 1.0 CD A:GLU319 3.1 22.1 1.0 CD2 A:HIS348 3.3 16.7 1.0 OE1 A:GLU319 3.5 19.0 1.0 CO A:CO502 3.6 24.9 1.0 CO A:CO503 3.8 22.4 0.3 CB A:ALA321 3.9 15.2 1.0 OE1 A:GLU343 3.9 33.4 1.0 CG A:GLU253 4.1 18.0 1.0 O A:HOH648 4.1 30.9 1.0 OD1 A:ASP383 4.2 22.0 1.0 ND1 A:HIS348 4.2 15.1 1.0 CG A:HIS348 4.4 16.7 1.0 CG A:GLU319 4.4 18.4 1.0 CD A:GLU343 4.4 25.7 1.0 CG A:PHE255 4.5 17.9 1.0 CB A:PHE255 4.5 16.5 1.0 OD2 A:ASP383 4.6 35.1 1.0 OH A:TYR355 4.6 44.9 1.0 CG A:ASP383 4.6 26.1 1.0 CD2 A:PHE255 4.7 18.3 1.0 CB A:GLU253 4.8 16.5 1.0 CG A:GLU343 4.9 19.1 1.0 O A:HOH509 5.0 18.4 1.0

Cobalt binding site 2 out of 3 in the Aminopeptidase S From S. Aureus


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Aminopeptidase S From S. Aureus within 5.0Å range: probe atom residue distance (Å) B Occ A:Co502 b:24.9 occ:1.00 OD1 A:ASP383 2.0 22.0 1.0 OE1 A:GLU319 2.1 19.0 1.0 O A:HOH883 2.2 27.2 1.0 NE2 A:HIS381 2.2 27.9 1.0 OH A:TYR355 2.5 44.9 1.0 CG A:ASP383 2.9 26.1 1.0 OD2 A:ASP383 2.9 35.1 1.0 CO A:CO503 3.0 22.4 0.3 CD A:GLU319 3.1 22.1 1.0 CE1 A:HIS381 3.1 28.0 1.0 CD2 A:HIS381 3.2 29.3 1.0 OE2 A:GLU319 3.5 19.8 1.0 CO A:CO501 3.6 24.4 1.0 CZ A:TYR355 3.7 40.0 1.0 O A:HOH533 3.9 24.7 1.0 CE2 A:TYR355 4.0 38.4 1.0 O A:HOH648 4.1 30.9 1.0 OE1 A:GLU343 4.3 33.4 1.0 ND1 A:HIS381 4.3 24.4 1.0 CB A:ASP383 4.3 19.5 1.0 CB A:ALA350 4.3 18.4 1.0 CG A:HIS381 4.3 24.9 1.0 CG A:GLU319 4.4 18.4 1.0 NE2 A:HIS348 4.6 16.6 1.0 CB A:GLU319 4.6 17.8 1.0 CD2 A:HIS348 4.7 16.7 1.0 CE1 A:TYR355 4.8 40.3 1.0 O A:HOH695 4.9 39.1 1.0 CA A:ASP383 5.0 20.7 1.0

Cobalt binding site 3 out of 3 in the Aminopeptidase S From S. Aureus


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Aminopeptidase S From S. Aureus within 5.0Å range: probe atom residue distance (Å) B Occ A:Co503 b:22.4 occ:0.30 O A:HOH883 1.9 27.2 1.0 OE1 A:GLU343 2.1 33.4 1.0 O A:HOH648 2.1 30.9 1.0 OD2 A:ASP383 2.1 35.1 1.0 O A:HOH695 2.3 39.1 1.0 CD A:GLU343 2.7 25.7 1.0 OE2 A:GLU343 2.8 29.9 1.0 CO A:CO502 3.0 24.9 1.0 CG A:ASP383 3.2 26.1 1.0 OD1 A:ASP383 3.5 22.0 1.0 CO A:CO501 3.8 24.4 1.0 O A:HOH775 4.0 31.8 1.0 OH A:TYR355 4.0 44.9 1.0 CG A:GLU343 4.2 19.1 1.0 O A:HOH533 4.2 24.7 1.0 ND2 A:ASN248 4.3 22.9 1.0 OE2 A:GLU253 4.3 20.7 1.0 CB A:ASP383 4.4 19.5 1.0 NE2 A:HIS348 4.6 16.6 1.0 CG2 A:THR339 4.7 24.9 1.0 OE1 A:GLU319 4.7 19.0 1.0 CB A:GLU343 4.8 17.1 1.0 NE2 A:HIS381 4.8 27.9 1.0 O A:HOH615 4.8 33.5 1.0

S.G.Odintsov, I.Sabala, G.Bourenkov, V.Rybin, M.Bochtler. Staphylococcus Aureus Aminopeptidase S Is A Founding Member of A New Peptidase Clan. J.Biol.Chem. V. 280 27792 2005.
ISSN: ISSN 0021-9258
PubMed: 15932875
DOI: 10.1074/JBC.M502023200