Cobalt in PDB 2bbc: Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form

The structure of Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form, PDB code: 2bbc was solved by J.Wuerges, G.Garau, S.Geremia, S.N.Fedosov, T.E.Petersen, L.Randaccio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.40
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	99.570, 99.570, 128.631, 90.00, 90.00, 120.00
R / Rfree (%)	20.4 / 24

The structure of Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Cobalt atom in the Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form (pdb code 2bbc). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form, PDB code: 2bbc:

Cobalt binding site 1 out of 1 in the Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Cobalamin-Complexed Bovine Transcobalamin in Trigonal Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Co0 b:37.8 occ:1.00 CO A:B120 0.0 37.8 1.0 N21 A:B120 1.9 35.7 1.0 N24 A:B120 1.9 36.3 1.0 N23 A:B120 1.9 39.1 1.0 N22 A:B120 1.9 36.4 1.0 N3B A:B120 2.1 32.1 1.0 NE2 A:HIS175 2.1 55.0 1.0 CE1 A:HIS175 2.6 61.0 1.0 C9 A:B120 2.8 38.0 1.0 C11 A:B120 2.8 41.2 1.0 C19 A:B120 2.8 35.1 1.0 C1 A:B120 2.9 33.6 1.0 C4 A:B120 2.9 34.8 1.0 C16 A:B120 2.9 36.9 1.0 C14 A:B120 2.9 41.2 1.0 C6 A:B120 3.0 35.5 1.0 C2B A:B120 3.0 30.4 1.0 C10 A:B120 3.1 39.3 1.0 C9B A:B120 3.2 29.6 1.0 C5 A:B120 3.3 35.4 1.0 C15 A:B120 3.4 39.0 1.0 CD2 A:HIS175 3.4 63.7 1.0 C20 A:B120 3.5 31.7 1.0 C4B A:B120 3.8 30.3 1.0 ND1 A:HIS175 3.8 64.5 1.0 C2 A:B120 4.1 33.3 1.0 C18 A:B120 4.1 34.4 1.0 C8 A:B120 4.1 34.8 1.0 C12 A:B120 4.2 44.5 1.0 C3 A:B120 4.2 34.0 1.0 C17 A:B120 4.2 34.6 1.0 C13 A:B120 4.2 44.1 1.0 N1B A:B120 4.2 30.9 1.0 C7 A:B120 4.2 35.4 1.0 CG A:HIS175 4.3 68.5 1.0 C8B A:B120 4.3 28.3 1.0 C26 A:B120 4.4 37.4 1.0 C41 A:B120 4.8 34.4 1.0 C46 A:B120 4.8 43.4 1.0 C35 A:B120 4.8 31.4 1.0 C53 A:B120 4.9 41.4 1.0 C48 A:B120 4.9 46.4 1.0 C37 A:B120 4.9 37.7 1.0 C54 A:B120 5.0 35.1 1.0

J.Wuerges, G.Garau, S.Geremia, S.N.Fedosov, T.E.Petersen, L.Randaccio. Structural Basis For Mammalian Vitamin B12 Transport By Transcobalamin. Proc.Natl.Acad.Sci.Usa V. 103 4386 2006.
ISSN: ISSN 0027-8424
PubMed: 16537422
DOI: 10.1073/PNAS.0509099103