Atomistry » Cobalt » PDB 2djl-2g6p » 2ew6
Atomistry »
  Cobalt »
    PDB 2djl-2g6p »
      2ew6 »

Cobalt in PDB 2ew6: Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor

Enzymatic activity of Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor

All present enzymatic activity of Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor:
3.5.1.88;

Protein crystallography data

The structure of Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor, PDB code: 2ew6 was solved by J.Cai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 11.99 / 2.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 42.170, 52.937, 91.792, 90.00, 90.00, 90.00
R / Rfree (%) 20.4 / 24.3

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor (pdb code 2ew6). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor, PDB code: 2ew6:

Cobalt binding site 1 out of 1 in 2ew6

Go back to Cobalt Binding Sites List in 2ew6
Cobalt binding site 1 out of 1 in the Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Helicobacter Pylori Peptide Deformylase in Complex with Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co300

b:20.2
occ:1.00
NE2 A:HIS138 2.1 17.7 1.0
NE2 A:HIS142 2.2 12.8 1.0
O A:HOH310 2.2 11.9 1.0
SG A:CYS96 2.4 18.8 1.0
CD2 A:HIS138 2.9 17.6 1.0
CD2 A:HIS142 3.0 13.0 1.0
CE1 A:HIS138 3.2 15.5 1.0
CE1 A:HIS142 3.2 13.1 1.0
NE2 A:GLN51 3.5 15.4 1.0
CB A:CYS96 3.5 18.2 1.0
O A:HOH319 3.7 17.3 1.0
O A:HOH311 3.7 16.3 1.0
OE1 A:GLN51 3.9 13.1 1.0
CD A:GLN51 3.9 13.2 1.0
OE2 A:GLU139 3.9 11.0 1.0
CA A:CYS96 4.0 18.9 1.0
CG A:HIS138 4.1 16.0 1.0
ND1 A:HIS138 4.2 16.6 1.0
CG A:HIS142 4.2 12.2 1.0
ND1 A:HIS142 4.3 14.3 1.0
OE1 A:GLU139 4.4 14.3 1.0
CD A:GLU139 4.5 12.2 1.0
C7 A:Y13200 4.6 61.3 1.0
N A:LEU97 4.7 17.9 1.0
O A:HOH307 4.7 10.3 1.0
O A:GLY95 4.7 19.5 1.0
C A:CYS96 4.8 18.8 1.0

Reference:

J.Cai, C.Han, T.Hu, J.Zhang, D.Wu, F.Wang, Y.Liu, J.Ding, K.Chen, J.Yue, X.Shen, H.Jiang. Peptide Deformylase Is A Potential Target For Anti-Helicobacter Pylori Drugs: Reverse Docking, Enzymatic Assay, and X-Ray Crystallography Validation Protein Sci. V. 15 2071 2006.
ISSN: ISSN 0961-8368
PubMed: 16882991
DOI: 10.1110/PS.062238406
Page generated: Tue Jul 30 15:07:35 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy