Cobalt in PDB 2ew7: Crystal Structure of Helicobacter Pylori Peptide Deformylase

All present enzymatic activity of Crystal Structure of Helicobacter Pylori Peptide Deformylase:
3.5.1.88;

The structure of Crystal Structure of Helicobacter Pylori Peptide Deformylase, PDB code: 2ew7 was solved by J.Cai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	11.69 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.254, 53.046, 91.156, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 24.2

The binding sites of Cobalt atom in the Crystal Structure of Helicobacter Pylori Peptide Deformylase (pdb code 2ew7). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of Helicobacter Pylori Peptide Deformylase, PDB code: 2ew7:

Cobalt binding site 1 out of 1 in the Crystal Structure of Helicobacter Pylori Peptide Deformylase


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Helicobacter Pylori Peptide Deformylase within 5.0Å range: probe atom residue distance (Å) B Occ A:Co300 b:17.7 occ:1.00 NE2 A:HIS142 2.1 16.3 1.0 NE2 A:HIS138 2.2 13.6 1.0 O A:HOH368 2.2 14.3 1.0 SG A:CYS96 2.4 18.1 1.0 CD2 A:HIS138 2.9 12.3 1.0 CD2 A:HIS142 3.0 15.1 1.0 CE1 A:HIS142 3.3 16.3 1.0 CE1 A:HIS138 3.3 14.6 1.0 NE2 A:GLN51 3.4 19.1 1.0 CB A:CYS96 3.5 16.4 1.0 O A:HOH308 3.7 17.5 1.0 O A:HOH330 3.7 15.7 1.0 CD A:GLN51 3.9 16.2 1.0 OE1 A:GLN51 3.9 16.7 1.0 OE2 A:GLU139 4.0 14.7 1.0 CA A:CYS96 4.1 17.2 1.0 CG A:HIS138 4.1 13.4 1.0 CG A:HIS142 4.2 16.4 1.0 ND1 A:HIS138 4.3 14.4 1.0 ND1 A:HIS142 4.3 14.6 1.0 OE1 A:GLU139 4.4 16.0 1.0 CD A:GLU139 4.5 15.6 1.0 N A:LEU97 4.6 17.0 1.0 O A:HOH314 4.6 12.4 1.0 C A:CYS96 4.8 18.8 1.0 O A:GLY95 4.8 18.4 1.0

J.Cai, C.Han, T.Hu, J.Zhang, D.Wu, F.Wang, Y.Liu, J.Ding, K.Chen, J.Yue, X.Shen, H.Jiang. Peptide Deformylase Is A Potential Target For Anti-Helicobacter Pylori Drugs: Reverse Docking, Enzymatic Assay, and X-Ray Crystallography Validation Protein Sci. V. 15 2071 2006.
ISSN: ISSN 0961-8368
PubMed: 16882991
DOI: 10.1110/PS.062238406