Cobalt in PDB 2h9a: Corrinoid Iron-Sulfur Protein

The structure of Corrinoid Iron-Sulfur Protein, PDB code: 2h9a was solved by H.Dobbek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	158.030, 44.270, 100.660, 90.00, 118.63, 90.00
R / Rfree (%)	20.3 / 26

The structure of Corrinoid Iron-Sulfur Protein also contains other interesting chemical elements:

Iodine	(I)	16 atoms
Iron	(Fe)	4 atoms

The binding sites of Cobalt atom in the Corrinoid Iron-Sulfur Protein (pdb code 2h9a). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Corrinoid Iron-Sulfur Protein, PDB code: 2h9a:

Cobalt binding site 1 out of 1 in the Corrinoid Iron-Sulfur Protein


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Corrinoid Iron-Sulfur Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Co1442 b:14.9 occ:1.00 CO A:B121442 0.0 14.9 1.0 N21 A:B121442 1.9 11.9 1.0 N22 A:B121442 1.9 10.8 1.0 N24 A:B121442 1.9 10.9 1.0 N23 A:B121442 1.9 9.9 1.0 O A:HOH1483 2.5 9.6 1.0 C9 A:B121442 2.8 11.4 1.0 C19 A:B121442 2.9 14.0 1.0 C4 A:B121442 2.9 9.9 1.0 C1 A:B121442 2.9 11.9 1.0 C11 A:B121442 2.9 10.6 1.0 C16 A:B121442 3.0 11.6 1.0 C6 A:B121442 3.0 11.8 1.0 C14 A:B121442 3.0 10.9 1.0 C10 A:B121442 3.2 9.6 1.0 C5 A:B121442 3.4 10.0 1.0 C20 A:B121442 3.4 10.9 1.0 C15 A:B121442 3.4 11.0 1.0 OG1 A:THR374 3.6 15.7 1.0 C18 A:B121442 4.1 14.2 1.0 C8 A:B121442 4.2 12.9 1.0 C2 A:B121442 4.2 12.3 1.0 C3 A:B121442 4.2 11.3 1.0 C17 A:B121442 4.3 12.9 1.0 C13 A:B121442 4.3 9.5 1.0 C12 A:B121442 4.3 9.4 1.0 C7 A:B121442 4.3 11.7 1.0 CG2 A:THR374 4.3 16.6 1.0 CB A:THR374 4.4 15.4 1.0 C26 A:B121442 4.6 13.2 1.0 CA A:THR374 4.7 13.7 1.0 C46 A:B121442 4.8 7.2 1.0 C35 A:B121442 4.9 11.6 1.0 C48 A:B121442 4.9 10.4 1.0 C41 A:B121442 5.0 15.4 1.0 C53 A:B121442 5.0 11.7 1.0 C37 A:B121442 5.0 12.8 1.0

T.Svetlitchnaia, V.Svetlitchnyi, O.Meyer, H.Dobbek. Structural Insights Into Methyltransfer Reactions of A Corrinoid Iron-Sulfur Protein Involved in Acetyl-Coa Synthesis. Proc.Natl.Acad.Sci.Usa V. 103 14331 2006.
ISSN: ISSN 0027-8424
PubMed: 16983091
DOI: 10.1073/PNAS.0601420103