Chemical elements
  Cobalt
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    PDB 1a0c-1epy
    PDB 1et4-1k7y
    PDB 1k98-1r6x
    PDB 1r8k-1v9b
    PDB 1vl3-212d
    PDB 222d-2eff
    PDB 2ehd-2j3z
    PDB 2j4j-2r1p
      2j4j
      2jf5
      2jja
      2jk5
      2k9c
      2krj
      2mat
      2npy
      2npz
      2nq6
      2nq7
      2o5s
      2o5t
      2oaz
      2oi6
      2oi7
      2oj3
      2opc
      2os3
      2oue
      2p7d
      2p7e
      2p7f
      2p8d
      2par
      2pau
      2pmv
      2pr1
      2prq
      2ps9
      2ptm
      2pxb
      2pxd
      2pxe
      2pxf
      2pxk
      2pxl
      2pxp
      2pxq
      2pxt
      2pxu
      2pxv
      2q6q
      2qb7
      2qtm
      2r1k
      2r1l
      2r1m
      2r1n
      2r1p
    PDB 2r2s-331d
    PDB 362d-3fqw
    PDB 3ft6-3igy
    PDB 3igz-3o0n
    PDB 3o0o-4req
    PDB 4xim-9icb

Cobalt in the structure of Crystal Structure of Type 1 Human Methionine Aminopeptidase in Complex With 3-(2,2-Dimethylpropionylamino)Pyridine-2-Carboxylic Acid Thiazole-2-Ylamide (pdb 2nq7)






The binding sites of Cobalt atom in the structure of Crystal Structure of Type 1 Human Methionine Aminopeptidase in Complex With 3-(2,2-Dimethylpropionylamino)Pyridine-2-Carboxylic Acid Thiazole-2-Ylamide (pdb code 2nq7). This binding sites where shown with 5.0 Angstroms radius around Cobalt atom.
The 2nq7 structure was solved by A.ADDLAGATTA, B.W.MATTHEWS, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)20.0-1.6
Space groupP1211
a (A)47.317
b (A)77.442
c (A)47.221
alpha (°)90.00
beta (°)92.31
gamma (°)90.00
Rfactor (%)19.5
Rfree (%)22.7


Cobalt Binding Sites:

Cobalt binding site 1 out of 3 in 2nq7


Cobalt binding site 1 out of 3 in 2nq7
Click to enlarge
stereopicture of Cobalt binding site 1 out of 3 in 2nq7
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cobalt in the PDB 2nq7. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Asp229, A: Ile230, A: Thr231, A: Asp240, A: Leu241, A: Asn242, A: Glu336, A: Glu367, A: Co402, A: Hoh476, A: Hoh480, A: Hoh494, A: Hoh547, A: Hoh624, A: Hoh625, A: Hoh626,

conact list:


AtomAtomDistance (A)
CoCB A:Asp2294.10
CoOD2 A:Asp2292.38
CoOD1 A:Asp2292.17
CoCG A:Asp2292.59
CoCA A:Asp2294.85
CoO A:Ile2304.49
CoN A:Ile2304.96
CoOG1 A:Thr2313.96
CoCB A:Asp2404.31
CoOD2 A:Asp2403.03
CoC A:Asp2404.75
CoOD1 A:Asp2402.03
CoCG A:Asp2402.86
CoCA A:Asp2404.85
CoO A:Leu2414.38
CoN A:Leu2414.41
CoC A:Leu2414.66
CoCA A:Leu2414.90
CoCB A:Asn2424.89
CoND2 A:Asn2424.11
CoOE1 A:Glu3364.53
CoOE2 A:Glu3364.29
CoCD A:Glu3364.70
CoOE1 A:Glu3672.17
CoOE2 A:Glu3673.24
CoCD A:Glu3673.05
CoCG A:Glu3674.47
CoCO A:Co4023.15
CoO A:Hoh4763.84
CoO A:Hoh4804.52
CoO A:Hoh4944.51
CoO A:Hoh5474.67
CoO A:Hoh6242.10
CoO A:Hoh6254.16
CoO A:Hoh6262.27

interactive model:


Cobalt binding site 2 out of 3 in 2nq7


Cobalt binding site 2 out of 3 in 2nq7
Click to enlarge
stereopicture of Cobalt binding site 2 out of 3 in 2nq7
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Cobalt in the PDB 2nq7. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Asp229, A: Asp240, A: His303, A: His310, A: Thr334, A: Glu336, A: Glu367, A: Co401, A: Hoh476, A: Hoh547, A: Hoh624, A: Hoh626,

conact list:


AtomAtomDistance (A)
CoOD2 A:Asp2294.95
CoCB A:Asp2404.16
CoOD2 A:Asp2402.00
CoOD1 A:Asp2403.45
CoCG A:Asp2402.98
CoNE2 A:His3032.12
CoND1 A:His3034.21
CoCD2 A:His3033.08
CoCE1 A:His3033.11
CoCG A:His3034.22
CoNE2 A:His3104.79
CoCD2 A:His3104.97
CoCB A:Thr3344.07
CoCG2 A:Thr3343.88
CoOG1 A:Thr3343.62
CoOE1 A:Glu3362.20
CoCB A:Glu3364.94
CoOE2 A:Glu3363.46
CoCD A:Glu3363.14
CoCG A:Glu3364.44
CoOE1 A:Glu3673.36
CoOE2 A:Glu3672.00
CoCD A:Glu3673.00
CoCG A:Glu3674.32
CoCO A:Co4013.15
CoO A:Hoh4763.77
CoO A:Hoh5474.78
CoO A:Hoh6241.93
CoO A:Hoh6264.28

interactive model:


Cobalt binding site 3 out of 3 in 2nq7


Cobalt binding site 3 out of 3 in 2nq7
Click to enlarge
stereopicture of Cobalt binding site 3 out of 3 in 2nq7
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Cobalt in the PDB 2nq7. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: His212, A: Asp229, A: His310, A: Glu336, A: Hm5410, A: Hoh476, A: Hoh480, A: Hoh547, A: Hoh624, A: Hoh625, A: Hoh626,

conact list:


AtomAtomDistance (A)
CoNE2 A:His2122.13
CoND1 A:His2124.21
CoCD2 A:His2123.08
CoCE1 A:His2123.12
CoCG A:His2124.22
CoOD2 A:Asp2294.53
CoNE2 A:His3104.03
CoCE1 A:His3104.66
CoOE2 A:Glu3364.63
CoS A:Hm54104.70
CoC9 A:Hm54104.37
CoN3 A:Hm54102.11
CoN2 A:Hm54102.26
CoO1 A:Hm54104.24
CoC8 A:Hm54104.90
CoC2 A:Hm54104.67
CoC6 A:Hm54103.15
CoN1 A:Hm54103.32
CoC5 A:Hm54102.98
CoC7 A:Hm54104.40
CoC4 A:Hm54103.07
CoC3 A:Hm54103.11
CoO A:Hoh4762.18
CoO A:Hoh4804.32
CoO A:Hoh5472.16
CoO A:Hoh6243.91
CoO A:Hoh6252.26
CoO A:Hoh6264.43

interactive model:




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