Cobalt in PDB 2qtm: Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase

All present enzymatic activity of Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase:
2.7.7.18;

The structure of Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase, PDB code: 2qtm was solved by V.C.Sershon, B.D.Santarsiero, A.D.Mesecar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.40
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	97.026, 97.026, 85.095, 90.00, 90.00, 120.00
R / Rfree (%)	21.7 / 26.5

The binding sites of Cobalt atom in the Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase (pdb code 2qtm). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase, PDB code: 2qtm:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ A:Co190 b:49.3 occ:1.00 NE2 A:HIS27 2.3 39.6 1.0 O B:HOH193 2.3 55.3 1.0 O A:HOH195 2.7 50.8 1.0 O B:HOH192 3.0 31.0 1.0 O A:HOH194 3.1 33.2 1.0 CE1 A:HIS27 3.2 35.7 1.0 CD2 A:HIS27 3.3 36.4 1.0 ND1 A:HIS27 4.3 35.5 1.0 CG A:HIS27 4.4 38.3 1.0 OG1 B:THR168 4.5 34.6 1.0 CB B:THR168 4.8 35.9 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ B:Co190 b:60.0 occ:1.00 NE2 B:HIS27 2.1 33.3 1.0 O A:HOH196 2.8 53.1 1.0 O B:HOH195 2.8 49.6 1.0 O B:HOH194 2.8 43.0 1.0 CE1 B:HIS27 2.9 30.1 1.0 CD2 B:HIS27 3.2 32.6 1.0 O A:HOH235 3.7 46.9 1.0 ND1 B:HIS27 4.1 32.5 1.0 CG B:HIS27 4.3 34.1 1.0 OG1 A:THR168 4.7 37.4 1.0 CB A:THR168 4.9 39.7 1.0 CE2 B:TYR26 5.0 39.8 1.0

V.C.Sershon, B.D.Santarsiero, A.D.Mesecar. Kinetic and X-Ray Structural Evidence For Negative Cooperativity in Substrate Binding to Nicotinate Mononucleotide Adenylyltransferase (Nmat) From Bacillus Anthracis. J.Mol.Biol. V. 385 867 2009.
ISSN: ISSN 0022-2836
PubMed: 18977360
DOI: 10.1016/J.JMB.2008.10.037