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Cobalt in PDB 2r2s: Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment

Enzymatic activity of Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment

All present enzymatic activity of Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment:
2.7.7.49;

Protein crystallography data

The structure of Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment, PDB code: 2r2s was solved by K.D.Goodwin, M.A.Lewis, E.C.Long, M.M.Georgiadis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.80
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 52.304, 144.508, 50.300, 90.00, 90.00, 90.00
R / Rfree (%) 22.8 / 30.8

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment (pdb code 2r2s). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment, PDB code: 2r2s:

Cobalt binding site 1 out of 1 in 2r2s

Go back to Cobalt Binding Sites List in 2r2s
Cobalt binding site 1 out of 1 in the Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Co(III)BLEOMYCINB2 Bound to D(Attagttataactaat) Complexed with Mmlv Rt Catalytic Fragment within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Co8

b:94.2
occ:1.00
 NG B:BLB9 1.9 92.8 1.0
NJ B:BLB9 2.0 94.1 1.0
NB B:BLB9 2.1 92.9 1.0
NC B:BLB9 2.3 93.0 1.0
NH B:BLB9 2.3 92.3 1.0
C29 B:BLB9 2.7 94.9 1.0
C7 B:BLB9 2.8 93.0 1.0
C6 B:BLB9 3.0 93.2 1.0
C27 B:BLB9 3.0 94.3 1.0
C3 B:BLB9 3.0 92.5 1.0
C2 B:BLB9 3.1 92.3 1.0
C10 B:BLB9 3.1 92.0 1.0
C12 B:BLB9 3.3 92.0 1.0
C13 B:BLB9 3.5 92.2 1.0
C14 B:BLB9 3.7 94.0 1.0
NI B:BLB9 4.0 94.4 1.0
C1 B:BLB9 4.0 91.9 1.0
NK B:BLB9 4.0 89.3 1.0
NL B:BLB9 4.1 73.5 1.0
C28 B:BLB9 4.1 94.2 1.0
NE B:BLB9 4.2 92.2 1.0
C30 B:BLB9 4.3 91.3 1.0
C34 B:BLB9 4.3 80.2 1.0
O40 B:BLB9 4.3 65.9 1.0
C31 B:BLB9 4.4 85.8 1.0
OH1 B:BLB9 4.4 95.3 1.0
C36 B:BLB9 4.5 77.3 1.0
O12 B:BLB9 4.5 91.1 1.0
C5 B:BLB9 4.5 93.8 1.0
O70 B:BLB9 4.6 88.3 1.0
C9 B:BLB9 4.6 91.4 1.0
C37 B:BLB9 4.6 70.7 1.0
NA B:BLB9 4.6 91.5 1.0
O1 B:BLB9 4.6 91.5 1.0
O4' B:DT6 4.7 60.2 1.0
C4' B:DT6 4.7 63.6 1.0
C40 B:BLB9 4.8 67.5 1.0
C33 B:BLB9 4.8 83.0 1.0
C8 B:BLB9 4.8 91.0 1.0

Reference:

K.D.Goodwin, M.A.Lewis, E.C.Long, M.M.Georgiadis. Crystal Structure of Dna-Bound Co(III) Bleomycin B2: Insights on Intercalation and Minor Groove Binding. Proc.Natl.Acad.Sci.Usa V. 105 5052 2008.
ISSN: ISSN 0027-8424
PubMed: 18362349
DOI: 10.1073/PNAS.0708143105
Page generated: Sun Dec 13 10:38:51 2020

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