Cobalt in the structure of Characterization Of Substrate Binding and Catalysis of the Potential Antibacterial Target N-Acetylglucosamine-1- Phosphate Uridyltransferase (Glmu) (pdb 2v0h)

The binding sites of Cobalt atom in the structure of Characterization Of Substrate Binding and Catalysis of the Potential Antibacterial Target N-Acetylglucosamine-1- Phosphate Uridyltransferase (Glmu) (pdb code 2v0h). This binding sites where shown with 5.0 Angstroms radius around Cobalt atom. The 2v0h structure was solved by I.MOCHALKIN, S.LIGHTLE, J.F.OHREN, N.Y.CHIRGADZE, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 111.8-1.8 Space group H32 a (A) 108.459 b (A) 108.459 c (A) 327.154 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 19.1 Rfree (%) 21.4 Cobalt Binding Sites: Cobalt binding site 1 out of 2 in 2v0h Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cobalt in the PDB 2v0h. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Gly381, A: Asp406, A: Co1464, A: Hoh2372, A: Hoh2388, A: Hoh2496, conact list: Atom Atom Distance (A) Co O A:Gly381 4.46 Co CB A:Asp406 4.39 Co OD2 A:Asp406 3.37 Co OD1 A:Asp406 2.07 Co CG A:Asp406 3.08 Co CA A:Asp406 4.87 Co CO A:Co1464 3.88 Co O A:Hoh2372 4.48 Co O A:Hoh2388 4.29 Co O A:Hoh2496 2.14 interactive model: Cobalt binding site 2 out of 2 in 2v0h Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Cobalt in the PDB 2v0h. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Asp406, A: Gln408, A: Co1463, A: Hoh2388, A: Hoh2432, A: Hoh2497, conact list: Atom Atom Distance (A) Co O A:Asp406 4.03 Co CB A:Asp406 4.22 Co OD2 A:Asp406 2.02 Co C A:Asp406 4.93 Co OD1 A:Asp406 3.41 Co CG A:Asp406 2.99 Co OE1 A:Gln408 4.01 Co CO A:Co1463 3.88 Co O A:Hoh2388 4.76 Co O A:Hoh2432 4.09 Co O A:Hoh2497 2.17 interactive model: