Cobalt in PDB 2xwq: Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
Enzymatic activity of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
All present enzymatic activity of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product:
4.99.1.3;
Protein crystallography data
The structure of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product, PDB code: 2xwq
was solved by
D.Ladakis,
A.A.Brindley,
E.Deery,
M.J.Warren,
R.W.Pickersgill,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
45.57 /
2.01
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
47.010,
99.000,
116.660,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
21.656 /
28.234
|
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
(pdb code 2xwq). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 4 binding sites of Cobalt where determined in the
Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product, PDB code: 2xwq:
Jump to Cobalt binding site number:
1;
2;
3;
4;
Cobalt binding site 1 out
of 4 in 2xwq
Go back to
Cobalt Binding Sites List in 2xwq
Cobalt binding site 1 out
of 4 in the Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Co1126
b:46.8
occ:0.50
|
CO
|
B:SIR1126
|
0.0
|
46.8
|
0.5
|
|
CO
|
B:SIR1126
|
0.1
|
25.2
|
0.5
|
|
NB
|
B:SIR1126
|
1.8
|
21.7
|
0.5
|
|
NB
|
B:SIR1126
|
1.9
|
43.7
|
0.5
|
|
NA
|
B:SIR1126
|
1.9
|
44.0
|
0.5
|
|
NC
|
B:SIR1126
|
1.9
|
17.4
|
0.5
|
|
ND
|
B:SIR1126
|
1.9
|
41.8
|
0.5
|
|
NC
|
B:SIR1126
|
2.0
|
42.3
|
0.5
|
|
NA
|
B:SIR1126
|
2.0
|
19.2
|
0.5
|
|
ND
|
B:SIR1126
|
2.0
|
17.3
|
0.5
|
|
O4B
|
B:SIR1126
|
2.8
|
23.3
|
0.5
|
|
C1B
|
B:SIR1126
|
2.8
|
22.6
|
0.5
|
|
C4B
|
B:SIR1126
|
2.8
|
21.9
|
0.5
|
|
C4A
|
B:SIR1126
|
2.9
|
44.4
|
0.5
|
|
C1B
|
B:SIR1126
|
2.9
|
44.3
|
0.5
|
|
C4B
|
B:SIR1126
|
2.9
|
44.0
|
0.5
|
|
C1A
|
B:SIR1126
|
2.9
|
43.1
|
0.5
|
|
C1C
|
B:SIR1126
|
2.9
|
13.7
|
0.5
|
|
C4A
|
B:SIR1126
|
3.0
|
21.9
|
0.5
|
|
C4C
|
B:SIR1126
|
3.0
|
15.5
|
0.5
|
|
C1C
|
B:SIR1126
|
3.0
|
40.9
|
0.5
|
|
C4D
|
B:SIR1126
|
3.0
|
39.8
|
0.5
|
|
C1D
|
B:SIR1126
|
3.0
|
40.9
|
0.5
|
|
C1A
|
B:SIR1126
|
3.0
|
19.6
|
0.5
|
|
C4D
|
B:SIR1126
|
3.0
|
13.8
|
0.5
|
|
C4C
|
B:SIR1126
|
3.0
|
40.8
|
0.5
|
|
C1D
|
B:SIR1126
|
3.1
|
15.1
|
0.5
|
|
CHB
|
B:SIR1126
|
3.2
|
44.0
|
0.5
|
|
CHB
|
B:SIR1126
|
3.3
|
20.9
|
0.5
|
|
CHC
|
B:SIR1126
|
3.3
|
15.8
|
0.5
|
|
CHC
|
B:SIR1126
|
3.3
|
43.4
|
0.5
|
|
CHA
|
B:SIR1126
|
3.4
|
40.6
|
0.5
|
|
CHA
|
B:SIR1126
|
3.4
|
17.5
|
0.5
|
|
CHD
|
B:SIR1126
|
3.4
|
40.0
|
0.5
|
|
CHD
|
B:SIR1126
|
3.4
|
13.0
|
0.5
|
|
O2A
|
B:SIR1126
|
3.6
|
54.6
|
0.5
|
|
CE1
|
B:HIS10
|
3.6
|
20.3
|
1.0
|
|
O
|
A:HOH2028
|
3.7
|
33.4
|
1.0
|
|
CE1
|
A:HIS10
|
3.7
|
17.9
|
1.0
|
|
CEB
|
B:SIR1126
|
3.8
|
27.1
|
0.5
|
|
C2B
|
B:SIR1126
|
4.0
|
24.9
|
0.5
|
|
C3B
|
B:SIR1126
|
4.1
|
24.5
|
0.5
|
|
C2C
|
B:SIR1126
|
4.2
|
11.6
|
0.5
|
|
C3A
|
B:SIR1126
|
4.2
|
44.8
|
0.5
|
|
C3C
|
B:SIR1126
|
4.2
|
13.4
|
0.5
|
|
NE2
|
B:HIS10
|
4.2
|
25.6
|
1.0
|
|
C2B
|
B:SIR1126
|
4.2
|
45.0
|
0.5
|
|
C2D
|
B:SIR1126
|
4.2
|
39.9
|
0.5
|
|
C3D
|
B:SIR1126
|
4.2
|
38.2
|
0.5
|
|
C2C
|
B:SIR1126
|
4.2
|
38.4
|
0.5
|
|
C3B
|
B:SIR1126
|
4.2
|
45.1
|
0.5
|
|
NE2
|
A:HIS10
|
4.2
|
21.0
|
1.0
|
|
C2A
|
B:SIR1126
|
4.2
|
43.5
|
0.5
|
|
C3D
|
B:SIR1126
|
4.2
|
12.1
|
0.5
|
|
C3C
|
B:SIR1126
|
4.3
|
40.1
|
0.5
|
|
C2D
|
B:SIR1126
|
4.3
|
14.1
|
0.5
|
|
CE1
|
B:HIS74
|
4.3
|
17.2
|
1.0
|
|
CDB
|
B:SIR1126
|
4.3
|
26.5
|
0.5
|
|
C3A
|
B:SIR1126
|
4.3
|
22.6
|
0.5
|
|
C2A
|
B:SIR1126
|
4.4
|
20.5
|
0.5
|
|
CE1
|
A:HIS74
|
4.4
|
18.9
|
1.0
|
|
CCA
|
B:SIR1126
|
4.5
|
53.4
|
0.5
|
|
ND1
|
A:HIS10
|
4.5
|
20.2
|
1.0
|
|
ND1
|
B:HIS10
|
4.5
|
24.9
|
1.0
|
|
O2B
|
B:SIR1126
|
4.6
|
48.0
|
0.5
|
|
O3B
|
B:SIR1126
|
4.7
|
27.0
|
0.5
|
|
O3A
|
B:SIR1126
|
4.7
|
21.7
|
0.5
|
|
CAA
|
B:SIR1126
|
4.7
|
47.4
|
0.5
|
|
CBB
|
B:SIR1126
|
4.8
|
29.6
|
0.5
|
|
NE2
|
B:HIS74
|
4.9
|
15.7
|
1.0
|
|
CDA
|
B:SIR1126
|
4.9
|
44.8
|
0.5
|
|
CBA
|
B:SIR1126
|
5.0
|
50.6
|
0.5
|
|
CAB
|
B:SIR1126
|
5.0
|
46.3
|
0.5
|
|
Cobalt binding site 2 out
of 4 in 2xwq
Go back to
Cobalt Binding Sites List in 2xwq
Cobalt binding site 2 out
of 4 in the Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Co1126
b:25.2
occ:0.50
|
CO
|
B:SIR1126
|
0.0
|
25.2
|
0.5
|
|
CO
|
B:SIR1126
|
0.1
|
46.8
|
0.5
|
|
NB
|
B:SIR1126
|
1.8
|
43.7
|
0.5
|
|
NB
|
B:SIR1126
|
1.9
|
21.7
|
0.5
|
|
NA
|
B:SIR1126
|
1.9
|
19.2
|
0.5
|
|
NA
|
B:SIR1126
|
1.9
|
44.0
|
0.5
|
|
NC
|
B:SIR1126
|
1.9
|
42.3
|
0.5
|
|
ND
|
B:SIR1126
|
2.0
|
17.3
|
0.5
|
|
NC
|
B:SIR1126
|
2.0
|
17.4
|
0.5
|
|
ND
|
B:SIR1126
|
2.0
|
41.8
|
0.5
|
|
C1B
|
B:SIR1126
|
2.8
|
44.3
|
0.5
|
|
O4B
|
B:SIR1126
|
2.8
|
23.3
|
0.5
|
|
C4B
|
B:SIR1126
|
2.8
|
44.0
|
0.5
|
|
C1B
|
B:SIR1126
|
2.8
|
22.6
|
0.5
|
|
C4A
|
B:SIR1126
|
2.9
|
44.4
|
0.5
|
|
C4B
|
B:SIR1126
|
2.9
|
21.9
|
0.5
|
|
C4A
|
B:SIR1126
|
2.9
|
21.9
|
0.5
|
|
C1C
|
B:SIR1126
|
2.9
|
40.9
|
0.5
|
|
C1A
|
B:SIR1126
|
2.9
|
19.6
|
0.5
|
|
C4D
|
B:SIR1126
|
3.0
|
13.8
|
0.5
|
|
C1A
|
B:SIR1126
|
3.0
|
43.1
|
0.5
|
|
C1C
|
B:SIR1126
|
3.0
|
13.7
|
0.5
|
|
C4C
|
B:SIR1126
|
3.0
|
40.8
|
0.5
|
|
C4C
|
B:SIR1126
|
3.0
|
15.5
|
0.5
|
|
C1D
|
B:SIR1126
|
3.1
|
15.1
|
0.5
|
|
C1D
|
B:SIR1126
|
3.1
|
40.9
|
0.5
|
|
C4D
|
B:SIR1126
|
3.1
|
39.8
|
0.5
|
|
CHB
|
B:SIR1126
|
3.2
|
44.0
|
0.5
|
|
CHB
|
B:SIR1126
|
3.2
|
20.9
|
0.5
|
|
CHC
|
B:SIR1126
|
3.3
|
43.4
|
0.5
|
|
CHA
|
B:SIR1126
|
3.3
|
17.5
|
0.5
|
|
CHC
|
B:SIR1126
|
3.4
|
15.8
|
0.5
|
|
CHA
|
B:SIR1126
|
3.4
|
40.6
|
0.5
|
|
CHD
|
B:SIR1126
|
3.5
|
40.0
|
0.5
|
|
CHD
|
B:SIR1126
|
3.5
|
13.0
|
0.5
|
|
O2A
|
B:SIR1126
|
3.6
|
54.6
|
0.5
|
|
CE1
|
B:HIS10
|
3.6
|
20.3
|
1.0
|
|
O
|
A:HOH2028
|
3.6
|
33.4
|
1.0
|
|
CE1
|
A:HIS10
|
3.7
|
17.9
|
1.0
|
|
CEB
|
B:SIR1126
|
3.8
|
27.1
|
0.5
|
|
C2B
|
B:SIR1126
|
4.0
|
24.9
|
0.5
|
|
C2B
|
B:SIR1126
|
4.1
|
45.0
|
0.5
|
|
C3B
|
B:SIR1126
|
4.1
|
24.5
|
0.5
|
|
C3B
|
B:SIR1126
|
4.1
|
45.1
|
0.5
|
|
C2C
|
B:SIR1126
|
4.2
|
38.4
|
0.5
|
|
NE2
|
B:HIS10
|
4.2
|
25.6
|
1.0
|
|
C3D
|
B:SIR1126
|
4.2
|
12.1
|
0.5
|
|
C3A
|
B:SIR1126
|
4.2
|
44.8
|
0.5
|
|
C3C
|
B:SIR1126
|
4.2
|
40.1
|
0.5
|
|
C3C
|
B:SIR1126
|
4.2
|
13.4
|
0.5
|
|
C2C
|
B:SIR1126
|
4.2
|
11.6
|
0.5
|
|
C2D
|
B:SIR1126
|
4.3
|
14.1
|
0.5
|
|
NE2
|
A:HIS10
|
4.3
|
21.0
|
1.0
|
|
C3A
|
B:SIR1126
|
4.3
|
22.6
|
0.5
|
|
C2A
|
B:SIR1126
|
4.3
|
20.5
|
0.5
|
|
C2A
|
B:SIR1126
|
4.3
|
43.5
|
0.5
|
|
C2D
|
B:SIR1126
|
4.3
|
39.9
|
0.5
|
|
C3D
|
B:SIR1126
|
4.3
|
38.2
|
0.5
|
|
CDB
|
B:SIR1126
|
4.4
|
26.5
|
0.5
|
|
CE1
|
A:HIS74
|
4.4
|
18.9
|
1.0
|
|
CE1
|
B:HIS74
|
4.4
|
17.2
|
1.0
|
|
CCA
|
B:SIR1126
|
4.5
|
53.4
|
0.5
|
|
ND1
|
A:HIS10
|
4.5
|
20.2
|
1.0
|
|
ND1
|
B:HIS10
|
4.5
|
24.9
|
1.0
|
|
O2B
|
B:SIR1126
|
4.6
|
48.0
|
0.5
|
|
O3A
|
B:SIR1126
|
4.7
|
21.7
|
0.5
|
|
O3B
|
B:SIR1126
|
4.7
|
27.0
|
0.5
|
|
CAA
|
B:SIR1126
|
4.8
|
47.4
|
0.5
|
|
CBB
|
B:SIR1126
|
4.9
|
29.6
|
0.5
|
|
CAB
|
B:SIR1126
|
4.9
|
46.3
|
0.5
|
|
CDB
|
B:SIR1126
|
4.9
|
43.7
|
0.5
|
|
NE2
|
B:HIS74
|
5.0
|
15.7
|
1.0
|
|
CDA
|
B:SIR1126
|
5.0
|
44.8
|
0.5
|
|
CBA
|
B:SIR1126
|
5.0
|
50.6
|
0.5
|
|
Cobalt binding site 3 out
of 4 in 2xwq
Go back to
Cobalt Binding Sites List in 2xwq
Cobalt binding site 3 out
of 4 in the Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 3 of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Co1126
b:0.1
occ:0.50
|
CO
|
D:SIR1126
|
0.0
|
0.1
|
0.5
|
|
CO
|
D:SIR1126
|
0.1
|
34.7
|
0.5
|
|
NB
|
D:SIR1126
|
1.8
|
0.6
|
0.5
|
|
NA
|
D:SIR1126
|
1.9
|
0.5
|
0.5
|
|
NA
|
D:SIR1126
|
1.9
|
31.1
|
0.5
|
|
NB
|
D:SIR1126
|
1.9
|
33.0
|
0.5
|
|
ND
|
D:SIR1126
|
1.9
|
0.3
|
0.5
|
|
NC
|
D:SIR1126
|
1.9
|
0.4
|
0.5
|
|
NC
|
D:SIR1126
|
2.0
|
30.2
|
0.5
|
|
ND
|
D:SIR1126
|
2.0
|
27.7
|
0.5
|
|
C1B
|
D:SIR1126
|
2.8
|
0.4
|
0.5
|
|
C4B
|
D:SIR1126
|
2.8
|
0.5
|
0.5
|
|
C4A
|
D:SIR1126
|
2.9
|
0.3
|
0.5
|
|
C1A
|
D:SIR1126
|
2.9
|
0.3
|
0.5
|
|
C4A
|
D:SIR1126
|
2.9
|
31.9
|
0.5
|
|
C1B
|
D:SIR1126
|
2.9
|
33.4
|
0.5
|
|
C1A
|
D:SIR1126
|
2.9
|
30.8
|
0.5
|
|
C4B
|
D:SIR1126
|
2.9
|
33.4
|
0.5
|
|
C4D
|
D:SIR1126
|
3.0
|
0.0
|
0.5
|
|
C1C
|
D:SIR1126
|
3.0
|
0.2
|
0.5
|
|
C1D
|
D:SIR1126
|
3.0
|
0.9
|
0.5
|
|
C1C
|
D:SIR1126
|
3.0
|
29.3
|
0.5
|
|
C4C
|
D:SIR1126
|
3.0
|
0.9
|
0.5
|
|
C4D
|
D:SIR1126
|
3.0
|
27.8
|
0.5
|
|
C4C
|
D:SIR1126
|
3.1
|
27.8
|
0.5
|
|
C1D
|
D:SIR1126
|
3.1
|
26.8
|
0.5
|
|
CHB
|
D:SIR1126
|
3.2
|
0.3
|
0.5
|
|
CE1
|
C:HIS10
|
3.3
|
39.8
|
1.0
|
|
CHB
|
D:SIR1126
|
3.3
|
32.6
|
0.5
|
|
CHC
|
D:SIR1126
|
3.3
|
0.4
|
0.5
|
|
CHA
|
D:SIR1126
|
3.3
|
0.1
|
0.5
|
|
CHA
|
D:SIR1126
|
3.3
|
28.1
|
0.5
|
|
CHC
|
D:SIR1126
|
3.4
|
32.3
|
0.5
|
|
CHD
|
D:SIR1126
|
3.4
|
0.8
|
0.5
|
|
CHD
|
D:SIR1126
|
3.5
|
26.6
|
0.5
|
|
O4B
|
D:SIR1126
|
3.7
|
37.9
|
0.5
|
|
NE2
|
D:HIS10
|
3.8
|
43.5
|
1.0
|
|
NE2
|
C:HIS10
|
3.8
|
40.5
|
1.0
|
|
C3B
|
D:SIR1126
|
4.0
|
0.4
|
0.5
|
|
C2B
|
D:SIR1126
|
4.1
|
0.2
|
0.5
|
|
C2A
|
D:SIR1126
|
4.2
|
0.2
|
0.5
|
|
C3A
|
D:SIR1126
|
4.2
|
0.2
|
0.5
|
|
C3D
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C2D
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C2C
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C3C
|
D:SIR1126
|
4.2
|
0.4
|
0.5
|
|
C2C
|
D:SIR1126
|
4.2
|
27.2
|
0.5
|
|
C3A
|
D:SIR1126
|
4.3
|
31.4
|
0.5
|
|
C2B
|
D:SIR1126
|
4.3
|
35.0
|
0.5
|
|
C3B
|
D:SIR1126
|
4.3
|
35.1
|
0.5
|
|
C3D
|
D:SIR1126
|
4.3
|
21.7
|
0.5
|
|
C2A
|
D:SIR1126
|
4.3
|
30.1
|
0.5
|
|
C3C
|
D:SIR1126
|
4.3
|
27.7
|
0.5
|
|
ND1
|
C:HIS10
|
4.3
|
42.1
|
1.0
|
|
C2D
|
D:SIR1126
|
4.3
|
22.6
|
0.5
|
|
CE1
|
D:HIS10
|
4.4
|
44.0
|
1.0
|
|
CE1
|
C:HIS74
|
4.5
|
39.6
|
1.0
|
|
CE1
|
D:HIS74
|
4.6
|
31.7
|
1.0
|
|
CD2
|
D:HIS10
|
4.6
|
41.1
|
1.0
|
|
CEB
|
D:SIR1126
|
4.6
|
35.8
|
0.5
|
|
CDA
|
D:SIR1126
|
4.7
|
0.1
|
0.5
|
|
CDB
|
D:SIR1126
|
4.7
|
1.0
|
0.5
|
|
NH1
|
D:ARG44
|
4.8
|
62.3
|
1.0
|
|
O3A
|
D:SIR1126
|
4.8
|
23.2
|
0.5
|
|
CBA
|
D:SIR1126
|
4.9
|
0.9
|
0.5
|
|
CD2
|
C:HIS10
|
5.0
|
38.9
|
1.0
|
|
CBB
|
D:SIR1126
|
5.0
|
35.0
|
0.5
|
|
Cobalt binding site 4 out
of 4 in 2xwq
Go back to
Cobalt Binding Sites List in 2xwq
Cobalt binding site 4 out
of 4 in the Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 4 of Anaerobic Cobalt Chelatase From Archeaoglobus Fulgidus ( Cbix) in Complex with Metalated Sirohydrochlorin Product within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Co1126
b:34.7
occ:0.50
|
CO
|
D:SIR1126
|
0.0
|
34.7
|
0.5
|
|
CO
|
D:SIR1126
|
0.1
|
0.1
|
0.5
|
|
NB
|
D:SIR1126
|
1.8
|
0.6
|
0.5
|
|
NA
|
D:SIR1126
|
1.9
|
0.5
|
0.5
|
|
NA
|
D:SIR1126
|
1.9
|
31.1
|
0.5
|
|
NB
|
D:SIR1126
|
1.9
|
33.0
|
0.5
|
|
NC
|
D:SIR1126
|
1.9
|
0.4
|
0.5
|
|
ND
|
D:SIR1126
|
1.9
|
0.3
|
0.5
|
|
NC
|
D:SIR1126
|
2.0
|
30.2
|
0.5
|
|
ND
|
D:SIR1126
|
2.0
|
27.7
|
0.5
|
|
C4B
|
D:SIR1126
|
2.8
|
0.5
|
0.5
|
|
C1B
|
D:SIR1126
|
2.8
|
0.4
|
0.5
|
|
C4A
|
D:SIR1126
|
2.9
|
31.9
|
0.5
|
|
C4A
|
D:SIR1126
|
2.9
|
0.3
|
0.5
|
|
C1A
|
D:SIR1126
|
2.9
|
0.3
|
0.5
|
|
C1B
|
D:SIR1126
|
2.9
|
33.4
|
0.5
|
|
C1A
|
D:SIR1126
|
2.9
|
30.8
|
0.5
|
|
C4B
|
D:SIR1126
|
2.9
|
33.4
|
0.5
|
|
C1C
|
D:SIR1126
|
3.0
|
0.2
|
0.5
|
|
C4D
|
D:SIR1126
|
3.0
|
0.0
|
0.5
|
|
C1D
|
D:SIR1126
|
3.0
|
0.9
|
0.5
|
|
C4C
|
D:SIR1126
|
3.0
|
0.9
|
0.5
|
|
C1C
|
D:SIR1126
|
3.0
|
29.3
|
0.5
|
|
C4D
|
D:SIR1126
|
3.0
|
27.8
|
0.5
|
|
C4C
|
D:SIR1126
|
3.1
|
27.8
|
0.5
|
|
C1D
|
D:SIR1126
|
3.1
|
26.8
|
0.5
|
|
CHB
|
D:SIR1126
|
3.2
|
0.3
|
0.5
|
|
CHB
|
D:SIR1126
|
3.3
|
32.6
|
0.5
|
|
CHC
|
D:SIR1126
|
3.3
|
0.4
|
0.5
|
|
CHA
|
D:SIR1126
|
3.3
|
28.1
|
0.5
|
|
CHA
|
D:SIR1126
|
3.3
|
0.1
|
0.5
|
|
CHC
|
D:SIR1126
|
3.4
|
32.3
|
0.5
|
|
CE1
|
C:HIS10
|
3.4
|
39.8
|
1.0
|
|
CHD
|
D:SIR1126
|
3.4
|
0.8
|
0.5
|
|
CHD
|
D:SIR1126
|
3.5
|
26.6
|
0.5
|
|
NE2
|
D:HIS10
|
3.7
|
43.5
|
1.0
|
|
O4B
|
D:SIR1126
|
3.8
|
37.9
|
0.5
|
|
NE2
|
C:HIS10
|
3.9
|
40.5
|
1.0
|
|
C3B
|
D:SIR1126
|
4.0
|
0.4
|
0.5
|
|
C2B
|
D:SIR1126
|
4.0
|
0.2
|
0.5
|
|
C2A
|
D:SIR1126
|
4.1
|
0.2
|
0.5
|
|
C3A
|
D:SIR1126
|
4.2
|
0.2
|
0.5
|
|
C2D
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C3D
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C2C
|
D:SIR1126
|
4.2
|
0.7
|
0.5
|
|
C3C
|
D:SIR1126
|
4.2
|
0.4
|
0.5
|
|
C3A
|
D:SIR1126
|
4.2
|
31.4
|
0.5
|
|
C2B
|
D:SIR1126
|
4.2
|
35.0
|
0.5
|
|
C2C
|
D:SIR1126
|
4.2
|
27.2
|
0.5
|
|
C2A
|
D:SIR1126
|
4.2
|
30.1
|
0.5
|
|
C3B
|
D:SIR1126
|
4.3
|
35.1
|
0.5
|
|
CE1
|
D:HIS10
|
4.3
|
44.0
|
1.0
|
|
C3D
|
D:SIR1126
|
4.3
|
21.7
|
0.5
|
|
C3C
|
D:SIR1126
|
4.3
|
27.7
|
0.5
|
|
C2D
|
D:SIR1126
|
4.3
|
22.6
|
0.5
|
|
ND1
|
C:HIS10
|
4.4
|
42.1
|
1.0
|
|
CE1
|
D:HIS74
|
4.5
|
31.7
|
1.0
|
|
CD2
|
D:HIS10
|
4.5
|
41.1
|
1.0
|
|
NH1
|
D:ARG44
|
4.6
|
62.3
|
1.0
|
|
CE1
|
C:HIS74
|
4.6
|
39.6
|
1.0
|
|
CEB
|
D:SIR1126
|
4.7
|
35.8
|
0.5
|
|
CDB
|
D:SIR1126
|
4.7
|
1.0
|
0.5
|
|
CDA
|
D:SIR1126
|
4.7
|
0.1
|
0.5
|
|
O3A
|
D:SIR1126
|
4.9
|
23.2
|
0.5
|
|
CBB
|
D:SIR1126
|
4.9
|
35.0
|
0.5
|
|
CBA
|
D:SIR1126
|
5.0
|
0.9
|
0.5
|
|
Reference:
C.V.Romao,
D.Ladakis,
S.A.Lobo,
M.A.Carrondo,
A.A.Brindley,
E.Deery,
P.M.Matias,
R.W.Pickersgill,
L.M.Saraiva,
M.J.Warren.
Evolution in A Family of Chelatases Facilitated By the Introduction of Active Site Asymmetry and Protein Oligomerization. Proc.Natl.Acad.Sci.Usa V. 108 97 2011.
ISSN: ISSN 0027-8424
PubMed: 21173279
DOI: 10.1073/PNAS.1014298108
Page generated: Tue Jul 30 15:42:17 2024
|
