Cobalt in PDB 2zgg: Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold

The structure of Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold, PDB code: 2zgg was solved by M.A.Mcdonough, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.91 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	48.959, 48.959, 79.042, 90.00, 90.00, 120.00
R / Rfree (%)	21.2 / 23.8

The structure of Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold also contains other interesting chemical elements:

Cadmium

(Cd)

1 atom

The binding sites of Cobalt atom in the Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold (pdb code 2zgg). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold, PDB code: 2zgg:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold within 5.0Å range: probe atom residue distance (Å) B Occ A:Co402 b:25.7 occ:1.00 O A:HOH1076 1.9 41.4 1.0 O A:HOH1075 2.2 51.4 1.0 O A:HOH1095 2.2 44.0 1.0 ND1 A:HIS69 2.5 20.4 1.0 O A:HOH1096 2.7 22.3 1.0 O A:HOH1117 3.0 49.9 1.0 CE1 A:HIS69 3.5 21.0 1.0 CG A:HIS69 3.5 25.0 1.0 CB A:HIS69 3.7 19.7 1.0 O A:HOH1017 3.7 40.5 1.0 O A:HOH1089 3.8 50.5 1.0 CA A:HIS69 3.8 20.5 1.0 O A:GLY35 4.3 21.2 1.0 O A:HOH1047 4.4 36.5 1.0 CA A:GLY35 4.6 14.8 1.0 NE2 A:HIS69 4.6 23.4 1.0 CD2 A:HIS69 4.6 20.6 1.0 C A:HIS69 4.7 20.6 1.0 O A:HOH1046 4.7 38.3 0.5 O A:GLY68 4.7 23.9 1.0 N A:HIS69 4.8 20.3 1.0 C A:GLY35 5.0 17.2 1.0

Cobalt binding site 2 out of 2 in the Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Asn-Hydroxylation Stabilises the Ankyrin Repeat Domain Fold within 5.0Å range: probe atom residue distance (Å) B Occ A:Co403 b:38.9 occ:0.50 O A:HOH1044 1.8 43.5 1.0 OD1 A:ASP37 2.1 29.7 1.0 O A:HOH1045 2.2 30.6 1.0 O A:HOH1046 2.4 38.3 0.5 CG A:ASP37 3.0 26.7 1.0 OD2 A:ASP37 3.2 28.2 1.0 O A:HOH1011 4.1 40.2 1.0 N A:ASP37 4.3 20.3 1.0 O A:HOH1117 4.4 49.9 1.0 CB A:ASP37 4.4 23.1 1.0 O A:GLY35 4.5 21.2 1.0 OD1 A:ASP38 4.6 24.1 1.0 O A:HOH1065 4.8 35.1 1.0 N A:ASP38 4.8 19.9 1.0 CA A:ASP37 4.9 21.0 1.0

L.Kelly, M.A.Mcdonough, M.L.Coleman, P.J.Ratcliffe, C.J.Schofield. Asparagine Beta-Hydroxylation Stabilizes the Ankyrin Repeat Domain Fold Mol Biosyst V. 5 52 2009.
ISSN: ISSN 1742-206X
PubMed: 19081931
DOI: 10.1039/B815271C