Cobalt in PDB 3bul: E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227)

All present enzymatic activity of E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227):
2.1.1.13;

The structure of E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227), PDB code: 3bul was solved by M.Koutmos, K.A.Pattridge, M.L.Ludwig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.07 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	106.529, 106.529, 137.150, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 24.7

The binding sites of Cobalt atom in the E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227) (pdb code 3bul). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227), PDB code: 3bul:

Cobalt binding site 1 out of 1 in the E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227)


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of E. Coli I690C/G743C Meth C-Terminal Fragment (649-1227) within 5.0Å range: probe atom residue distance (Å) B Occ A:Co1301 b:25.5 occ:1.00 CO A:B121301 0.0 25.5 1.0 N21 A:B121301 1.9 26.7 1.0 N23 A:B121301 1.9 28.5 1.0 N22 A:B121301 1.9 27.2 1.0 N24 A:B121301 1.9 26.6 1.0 C19 A:B121301 2.8 28.9 1.0 C4 A:B121301 2.8 30.2 1.0 C1 A:B121301 2.9 29.8 1.0 C9 A:B121301 2.9 21.2 1.0 C11 A:B121301 2.9 25.5 1.0 C14 A:B121301 2.9 28.7 1.0 C6 A:B121301 2.9 24.9 1.0 C16 A:B121301 3.0 26.2 1.0 C10 A:B121301 3.2 21.3 1.0 C5 A:B121301 3.3 26.6 1.0 C15 A:B121301 3.4 27.6 1.0 C20 A:B121301 3.6 27.3 1.0 C2 A:B121301 4.0 33.0 1.0 C3 A:B121301 4.1 33.1 1.0 C18 A:B121301 4.1 32.1 1.0 C13 A:B121301 4.2 26.4 1.0 C8 A:B121301 4.2 22.4 1.0 C17 A:B121301 4.2 31.6 1.0 C7 A:B121301 4.2 26.8 1.0 C12 A:B121301 4.3 26.9 1.0 C49 A:B121301 4.5 43.0 1.0 OH A:TYR1139 4.5 36.1 1.0 C26 A:B121301 4.5 36.7 1.0 C35 A:B121301 4.8 20.0 1.0 C37 A:B121301 4.8 24.9 1.0 CE1 A:TYR1139 4.9 30.7 1.0 C30 A:B121301 4.9 34.1 1.0 C53 A:B121301 4.9 25.9 1.0 CD2 A:LEU806 4.9 37.9 1.0 C41 A:B121301 4.9 14.5 1.0 CD1 A:LEU806 4.9 37.4 1.0 C48 A:B121301 5.0 32.8 1.0 C46 A:B121301 5.0 22.5 1.0 C54 A:B121301 5.0 33.2 1.0

S.Datta, M.Koutmos, K.A.Pattridge, M.L.Ludwig, R.G.Matthews. A Disulfide-Stabilized Conformer of Methionine Synthase Reveals An Unexpected Role For the Histidine Ligand of the Cobalamin Cofactor. Proc.Natl.Acad.Sci.Usa V. 105 4115 2008.
ISSN: ISSN 0027-8424
PubMed: 18332423
DOI: 10.1073/PNAS.0800329105