Cobalt in PDB 3cqs: A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases

The structure of A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases, PDB code: 3cqs was solved by A.T.Torelli, R.C.Spitale, J.Krucinska, J.E.Wedekind, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.92 / 2.80
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	93.160, 93.160, 129.050, 90.00, 90.00, 120.00
R / Rfree (%)	21.7 / 25.4

The binding sites of Cobalt atom in the A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases (pdb code 3cqs). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases, PDB code: 3cqs:

Cobalt binding site 1 out of 1 in the A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities with Protein Ribonucleases within 5.0Å range: probe atom residue distance (Å) B Occ B:Co1 b:100.0 occ:1.00 CO B:NCO1 0.0 100.0 1.0 N5 B:NCO1 1.9 98.6 1.0 N4 B:NCO1 2.0 96.6 1.0 N3 B:NCO1 2.0 97.0 1.0 N2 B:NCO1 2.0 97.3 1.0 N1 B:NCO1 2.0 97.5 1.0 N6 B:NCO1 2.0 96.8 1.0 OP2 C:A40 3.8 75.2 1.0 OP2 C:U41 3.8 63.6 1.0 OP2 B:A20 4.1 80.9 1.0 N7 B:G21 4.1 71.7 1.0 O6 B:G21 4.2 72.6 1.0 O5' C:A40 4.8 71.7 1.0 P C:A40 4.8 77.0 1.0 C5 B:G21 4.9 71.0 1.0 C6 B:G21 4.9 71.2 1.0 N7 B:A20 5.0 77.7 1.0

A.T.Torelli, R.C.Spitale, J.Krucinska, J.E.Wedekind. Shared Traits on the Reaction Coordinates of Ribonuclease and An Rna Enzyme Biochem.Biophys.Res.Commun. V. 371 154 2008.
ISSN: ISSN 0006-291X
PubMed: 18423397
DOI: 10.1016/J.BBRC.2008.04.036