Cobalt in the structure of A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities With Protein Ribonucleases (pdb 3cqs)

The binding sites of Cobalt atom in the structure of A 3'-Oh, 2',5'-Phosphodiester Substitution in the Hairpin Ribozyme Active Site Reveals Similarities With Protein Ribonucleases (pdb code 3cqs). This binding sites where shown with 5.0 Angstroms radius around Cobalt atom. The 3cqs structure was solved by A.T.TORELLI, R.C.SPITALE, J.KRUCINSKA, J.E.WEDEKIND, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 22.9-2.8 Space group P6122 a (A) 93.160 b (A) 93.160 c (A) 129.050 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 21.7 Rfree (%) 25.4 Cobalt Binding Sites: Cobalt binding site 1 out of 1 in 3cqs Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cobalt in the PDB 3cqs. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: A20, B: G21, C: A40, C: U41, B: Nco1, conact list: Atom Atom Distance (A) Co N7 B:A20 4.99 Co OP2 B:A20 4.07 Co C6 B:G21 4.94 Co C5 B:G21 4.93 Co N7 B:G21 4.15 Co O6 B:G21 4.22 Co P C:A40 4.84 Co OP2 C:A40 3.77 Co O5' C:A40 4.82 Co OP2 C:U41 3.79 Co N1 B:Nco1 2.01 Co N6 B:Nco1 2.01 Co CO B:Nco1 0.00 Co N3 B:Nco1 1.99 Co N2 B:Nco1 2.01 Co N5 B:Nco1 1.95 Co N4 B:Nco1 1.96 interactive model: