Cobalt in PDB 3far: Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site

The structure of Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site, PDB code: 3far was solved by E.Ennifar, P.Dumas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.99 / 2.40
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	43.689, 47.541, 57.735, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 28.4

The structure of Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Cobalt atom in the Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site (pdb code 3far). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site, PDB code: 3far:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Co24 b:39.4 occ:0.67 O A:HOH47 1.8 41.3 1.0 O A:HOH43 2.0 60.6 1.0 O A:HOH35 2.2 26.2 1.0 N7 A:G10 2.4 34.8 1.0 C8 A:G10 3.3 36.1 1.0 C5 A:G10 3.4 34.7 1.0 O6 A:G10 3.5 32.3 1.0 C6 A:G10 3.8 33.8 1.0 O2' A:G7 3.8 50.4 1.0 OP1 A:A9 4.1 38.3 1.0 N1 B:A16 4.3 38.9 1.0 OP2 A:A9 4.5 33.2 1.0 N9 A:G10 4.5 36.8 1.0 C4 A:G10 4.6 35.6 1.0 N4 A:C11 4.6 43.5 1.0 P A:A9 4.7 37.2 1.0 N6 B:A16 4.9 38.0 1.0 C2 B:A16 5.0 38.6 1.0

Cobalt binding site 2 out of 2 in the Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Co27 b:64.8 occ:0.76 N7 B:G10 2.2 52.2 1.0 C8 B:G10 2.8 50.8 1.0 OP1 B:A9 3.0 59.2 1.0 OP2 B:A9 3.2 59.6 1.0 C5 B:G10 3.4 50.7 1.0 P B:A9 3.5 61.0 1.0 O A:HOH36 3.5 62.0 1.0 N9 B:G10 4.1 49.9 1.0 N1 A:A16 4.2 42.5 1.0 O6 B:G10 4.2 52.0 1.0 C6 B:G10 4.2 51.4 1.0 O3' B:A8 4.3 59.6 1.0 O B:HOH34 4.4 43.2 1.0 C4 B:G10 4.4 50.2 1.0 O2' B:G7 4.8 56.8 1.0 C2 A:A16 4.8 42.6 1.0 N6 A:A16 4.9 39.8 1.0 O5' B:A9 4.9 56.9 1.0 C6 A:A16 5.0 41.7 1.0

E.Ennifar, P.Walter, P.Dumas. Cation-Dependent Self-Cleavage Activity in the Duplex Form of the Subtype-B Hiv-1 Rna Dimerization Initiation Site To Be Published.