Cobalt in the structure of Phosphorylation of Self-Peptides Alters Human Leukocyte Antigen Class I-Restricted Antigen Presentation and Generates Tumor Specific Epitopes (pdb 3fqw)

The binding sites of Cobalt atom in the structure of Phosphorylation of Self-Peptides Alters Human Leukocyte Antigen Class I-Restricted Antigen Presentation and Generates Tumor Specific Epitopes (pdb code 3fqw). This binding sites where shown with 5.0 Angstroms radius around Cobalt atom. The 3fqw structure was solved by J.PETERSEN, J.ROSSJOHN, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 23.7-1.9 Space group P212121 a (A) 59.982 b (A) 79.378 c (A) 111.292 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 16.9 Rfree (%) 19.6 Cobalt Binding Sites: Cobalt binding site 1 out of 1 in 3fqw Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Cobalt in the PDB 3fqw. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Cobalt atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: His50, B: Hoh101, B: Hoh290, B: Hoh318, B: Hoh319, conact list: Atom Atom Distance (A) Co NE2 B:His50 2.26 Co ND1 B:His50 4.33 Co CD2 B:His50 3.21 Co CE1 B:His50 3.23 Co CG B:His50 4.36 Co O B:Hoh101 4.43 Co O B:Hoh290 1.91 Co O B:Hoh318 2.84 Co O B:Hoh319 2.27 interactive model: