Cobalt in PDB 3som: Crystal Structure of Human Mmachc
Protein crystallography data
The structure of Crystal Structure of Human Mmachc, PDB code: 3som
was solved by
T.Krojer,
D.S.Froese,
F.Von Delft,
J.R.Muniz,
C.Gileadi,
M.Vollmar,
C.Bountra,
C.H.Arrowsmith,
J.Weigelt,
A.Edwards,
R.A.Gravel,
W.W.Yue,
U.Oppermann,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
19.86 /
2.40
|
|
Space group
|
P 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
71.664,
71.960,
300.055,
88.53,
85.25,
83.76
|
|
R / Rfree (%)
|
18.2 /
20.6
|
Cobalt Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
16;
Binding sites:
The binding sites of Cobalt atom in the Crystal Structure of Human Mmachc
(pdb code 3som). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 16 binding sites of Cobalt where determined in the
Crystal Structure of Human Mmachc, PDB code: 3som:
Jump to Cobalt binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Cobalt binding site 1 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 1 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Co301
b:31.7
occ:1.00
|
CO
|
A:B12301
|
0.0
|
31.7
|
1.0
|
|
N21
|
A:B12301
|
1.9
|
28.9
|
1.0
|
|
N22
|
A:B12301
|
1.9
|
32.6
|
1.0
|
|
N23
|
A:B12301
|
1.9
|
30.7
|
1.0
|
|
N24
|
A:B12301
|
1.9
|
31.3
|
1.0
|
|
C5'
|
B:5AD401
|
2.5
|
43.3
|
1.0
|
|
C19
|
A:B12301
|
2.7
|
29.4
|
1.0
|
|
C16
|
A:B12301
|
2.8
|
29.3
|
1.0
|
|
C1
|
A:B12301
|
2.8
|
32.0
|
1.0
|
|
C9
|
A:B12301
|
2.9
|
31.2
|
1.0
|
|
C14
|
A:B12301
|
3.0
|
31.0
|
1.0
|
|
C4
|
A:B12301
|
3.0
|
31.7
|
1.0
|
|
C11
|
A:B12301
|
3.0
|
31.5
|
1.0
|
|
C6
|
A:B12301
|
3.0
|
31.1
|
1.0
|
|
C15
|
A:B12301
|
3.3
|
30.8
|
1.0
|
|
C10
|
A:B12301
|
3.4
|
30.8
|
1.0
|
|
C5
|
A:B12301
|
3.4
|
32.7
|
1.0
|
|
C4'
|
B:5AD401
|
3.5
|
43.1
|
1.0
|
|
O4'
|
B:5AD401
|
3.5
|
41.3
|
1.0
|
|
C20
|
A:B12301
|
3.5
|
30.6
|
1.0
|
|
N52
|
A:B12301
|
3.9
|
27.4
|
1.0
|
|
C17
|
A:B12301
|
4.0
|
33.0
|
1.0
|
|
C18
|
A:B12301
|
4.0
|
30.4
|
1.0
|
|
C2
|
A:B12301
|
4.1
|
32.1
|
1.0
|
|
O44
|
A:B12301
|
4.2
|
33.5
|
1.0
|
|
C8
|
A:B12301
|
4.2
|
33.5
|
1.0
|
|
C3
|
A:B12301
|
4.2
|
30.5
|
1.0
|
|
C13
|
A:B12301
|
4.3
|
31.1
|
1.0
|
|
C12
|
A:B12301
|
4.3
|
32.3
|
1.0
|
|
C7
|
A:B12301
|
4.3
|
34.9
|
1.0
|
|
C50
|
A:B12301
|
4.5
|
33.2
|
1.0
|
|
C26
|
A:B12301
|
4.6
|
31.9
|
1.0
|
|
C49
|
A:B12301
|
4.7
|
31.4
|
1.0
|
|
C53
|
A:B12301
|
4.8
|
29.4
|
1.0
|
|
C43
|
A:B12301
|
4.8
|
42.9
|
1.0
|
|
C54
|
A:B12301
|
4.8
|
30.2
|
1.0
|
|
C46
|
A:B12301
|
4.9
|
28.9
|
1.0
|
|
C3'
|
B:5AD401
|
4.9
|
42.8
|
1.0
|
|
C1'
|
B:5AD401
|
4.9
|
40.3
|
1.0
|
|
C42
|
A:B12301
|
4.9
|
38.6
|
1.0
|
|
C37
|
A:B12301
|
4.9
|
34.9
|
1.0
|
|
C35
|
A:B12301
|
4.9
|
33.8
|
1.0
|
|
Cobalt binding site 2 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 2 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Co301
b:32.7
occ:1.00
|
CO
|
B:B12301
|
0.0
|
32.7
|
1.0
|
|
N21
|
B:B12301
|
1.9
|
30.5
|
1.0
|
|
N22
|
B:B12301
|
1.9
|
34.8
|
1.0
|
|
N23
|
B:B12301
|
1.9
|
32.3
|
1.0
|
|
N24
|
B:B12301
|
1.9
|
31.3
|
1.0
|
|
C5'
|
A:5AD401
|
2.5
|
41.2
|
1.0
|
|
C19
|
B:B12301
|
2.7
|
29.5
|
1.0
|
|
C16
|
B:B12301
|
2.8
|
29.4
|
1.0
|
|
C1
|
B:B12301
|
2.8
|
32.8
|
1.0
|
|
C9
|
B:B12301
|
2.9
|
33.6
|
1.0
|
|
C4
|
B:B12301
|
3.0
|
34.0
|
1.0
|
|
C14
|
B:B12301
|
3.0
|
32.3
|
1.0
|
|
C11
|
B:B12301
|
3.0
|
33.1
|
1.0
|
|
C6
|
B:B12301
|
3.0
|
33.4
|
1.0
|
|
C15
|
B:B12301
|
3.3
|
31.8
|
1.0
|
|
C10
|
B:B12301
|
3.4
|
32.6
|
1.0
|
|
C5
|
B:B12301
|
3.4
|
35.0
|
1.0
|
|
C4'
|
A:5AD401
|
3.5
|
42.9
|
1.0
|
|
O4'
|
A:5AD401
|
3.5
|
43.6
|
1.0
|
|
C20
|
B:B12301
|
3.5
|
31.6
|
1.0
|
|
N52
|
B:B12301
|
3.9
|
29.7
|
1.0
|
|
C17
|
B:B12301
|
4.0
|
32.9
|
1.0
|
|
C18
|
B:B12301
|
4.0
|
30.1
|
1.0
|
|
C2
|
B:B12301
|
4.1
|
33.4
|
1.0
|
|
O44
|
B:B12301
|
4.2
|
46.5
|
1.0
|
|
C3
|
B:B12301
|
4.2
|
33.1
|
1.0
|
|
C8
|
B:B12301
|
4.2
|
36.4
|
1.0
|
|
C13
|
B:B12301
|
4.3
|
32.4
|
1.0
|
|
C12
|
B:B12301
|
4.3
|
33.6
|
1.0
|
|
C7
|
B:B12301
|
4.3
|
38.4
|
1.0
|
|
C50
|
B:B12301
|
4.5
|
36.3
|
1.0
|
|
C26
|
B:B12301
|
4.6
|
33.9
|
1.0
|
|
C49
|
B:B12301
|
4.7
|
33.7
|
1.0
|
|
C53
|
B:B12301
|
4.8
|
30.6
|
1.0
|
|
C43
|
B:B12301
|
4.8
|
46.7
|
1.0
|
|
C54
|
B:B12301
|
4.8
|
30.0
|
1.0
|
|
C3'
|
A:5AD401
|
4.9
|
45.4
|
1.0
|
|
C46
|
B:B12301
|
4.9
|
30.3
|
1.0
|
|
C1'
|
A:5AD401
|
4.9
|
44.4
|
1.0
|
|
C42
|
B:B12301
|
4.9
|
42.3
|
1.0
|
|
C35
|
B:B12301
|
4.9
|
36.2
|
1.0
|
|
C37
|
B:B12301
|
4.9
|
38.8
|
1.0
|
|
Cobalt binding site 3 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 3 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 3 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Co301
b:32.5
occ:1.00
|
CO
|
C:B12301
|
0.0
|
32.5
|
1.0
|
|
N21
|
C:B12301
|
1.9
|
31.0
|
1.0
|
|
N22
|
C:B12301
|
1.9
|
34.9
|
1.0
|
|
N23
|
C:B12301
|
1.9
|
32.0
|
1.0
|
|
N24
|
C:B12301
|
1.9
|
31.9
|
1.0
|
|
C5'
|
D:5AD401
|
2.5
|
46.5
|
1.0
|
|
C19
|
C:B12301
|
2.7
|
30.1
|
1.0
|
|
C16
|
C:B12301
|
2.8
|
30.0
|
1.0
|
|
C1
|
C:B12301
|
2.8
|
33.4
|
1.0
|
|
C9
|
C:B12301
|
2.9
|
33.4
|
1.0
|
|
C14
|
C:B12301
|
3.0
|
32.4
|
1.0
|
|
C4
|
C:B12301
|
3.0
|
34.0
|
1.0
|
|
C11
|
C:B12301
|
3.0
|
32.5
|
1.0
|
|
C6
|
C:B12301
|
3.0
|
33.5
|
1.0
|
|
C15
|
C:B12301
|
3.3
|
32.4
|
1.0
|
|
C10
|
C:B12301
|
3.4
|
31.9
|
1.0
|
|
C5
|
C:B12301
|
3.4
|
35.0
|
1.0
|
|
C4'
|
D:5AD401
|
3.4
|
45.1
|
1.0
|
|
O4'
|
D:5AD401
|
3.5
|
44.0
|
1.0
|
|
C20
|
C:B12301
|
3.5
|
32.2
|
1.0
|
|
N52
|
C:B12301
|
3.9
|
32.5
|
1.0
|
|
C17
|
C:B12301
|
4.0
|
33.7
|
1.0
|
|
C18
|
C:B12301
|
4.0
|
31.1
|
1.0
|
|
C2
|
C:B12301
|
4.1
|
33.6
|
1.0
|
|
O44
|
C:B12301
|
4.2
|
40.0
|
1.0
|
|
C3
|
C:B12301
|
4.2
|
32.9
|
1.0
|
|
C8
|
C:B12301
|
4.2
|
36.1
|
1.0
|
|
C13
|
C:B12301
|
4.3
|
32.4
|
1.0
|
|
C12
|
C:B12301
|
4.3
|
32.6
|
1.0
|
|
C7
|
C:B12301
|
4.3
|
38.9
|
1.0
|
|
C50
|
C:B12301
|
4.5
|
36.9
|
1.0
|
|
C26
|
C:B12301
|
4.6
|
34.7
|
1.0
|
|
C49
|
C:B12301
|
4.7
|
34.0
|
1.0
|
|
C53
|
C:B12301
|
4.8
|
31.9
|
1.0
|
|
C43
|
C:B12301
|
4.8
|
41.6
|
1.0
|
|
C54
|
C:B12301
|
4.8
|
30.7
|
1.0
|
|
C46
|
C:B12301
|
4.8
|
28.8
|
1.0
|
|
C3'
|
D:5AD401
|
4.8
|
45.5
|
1.0
|
|
C1'
|
D:5AD401
|
4.9
|
41.6
|
1.0
|
|
C37
|
C:B12301
|
4.9
|
40.1
|
1.0
|
|
C35
|
C:B12301
|
4.9
|
36.4
|
1.0
|
|
C42
|
C:B12301
|
4.9
|
38.6
|
1.0
|
|
Cobalt binding site 4 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 4 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 4 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Co301
b:25.5
occ:1.00
|
CO
|
D:B12301
|
0.0
|
25.5
|
1.0
|
|
N21
|
D:B12301
|
1.9
|
22.5
|
1.0
|
|
N22
|
D:B12301
|
1.9
|
26.3
|
1.0
|
|
N23
|
D:B12301
|
1.9
|
24.4
|
1.0
|
|
N24
|
D:B12301
|
2.0
|
25.4
|
1.0
|
|
C5'
|
C:5AD401
|
2.5
|
46.8
|
1.0
|
|
C19
|
D:B12301
|
2.7
|
23.3
|
1.0
|
|
C16
|
D:B12301
|
2.8
|
23.6
|
1.0
|
|
C1
|
D:B12301
|
2.8
|
26.2
|
1.0
|
|
C9
|
D:B12301
|
2.9
|
25.4
|
1.0
|
|
C14
|
D:B12301
|
3.0
|
24.8
|
1.0
|
|
C4
|
D:B12301
|
3.0
|
25.6
|
1.0
|
|
C11
|
D:B12301
|
3.0
|
25.2
|
1.0
|
|
C6
|
D:B12301
|
3.0
|
25.0
|
1.0
|
|
C15
|
D:B12301
|
3.3
|
25.4
|
1.0
|
|
C10
|
D:B12301
|
3.4
|
24.8
|
1.0
|
|
C5
|
D:B12301
|
3.4
|
26.6
|
1.0
|
|
C4'
|
C:5AD401
|
3.4
|
46.1
|
1.0
|
|
O4'
|
C:5AD401
|
3.5
|
44.0
|
1.0
|
|
C20
|
D:B12301
|
3.5
|
24.6
|
1.0
|
|
N52
|
D:B12301
|
3.9
|
17.1
|
1.0
|
|
C18
|
D:B12301
|
4.1
|
24.3
|
1.0
|
|
C17
|
D:B12301
|
4.1
|
27.4
|
1.0
|
|
C2
|
D:B12301
|
4.1
|
26.5
|
1.0
|
|
O44
|
D:B12301
|
4.2
|
27.0
|
1.0
|
|
C8
|
D:B12301
|
4.2
|
28.6
|
1.0
|
|
C3
|
D:B12301
|
4.2
|
24.9
|
1.0
|
|
C12
|
D:B12301
|
4.3
|
24.7
|
1.0
|
|
C13
|
D:B12301
|
4.3
|
24.4
|
1.0
|
|
C7
|
D:B12301
|
4.3
|
29.6
|
1.0
|
|
C50
|
D:B12301
|
4.5
|
22.8
|
1.0
|
|
C26
|
D:B12301
|
4.6
|
26.9
|
1.0
|
|
C49
|
D:B12301
|
4.7
|
22.5
|
1.0
|
|
C43
|
D:B12301
|
4.8
|
34.3
|
1.0
|
|
C53
|
D:B12301
|
4.8
|
24.7
|
1.0
|
|
C54
|
D:B12301
|
4.8
|
24.7
|
1.0
|
|
C46
|
D:B12301
|
4.8
|
21.3
|
1.0
|
|
C3'
|
C:5AD401
|
4.8
|
46.5
|
1.0
|
|
C1'
|
C:5AD401
|
4.9
|
41.5
|
1.0
|
|
C42
|
D:B12301
|
4.9
|
31.8
|
1.0
|
|
C37
|
D:B12301
|
4.9
|
29.8
|
1.0
|
|
C35
|
D:B12301
|
4.9
|
28.0
|
1.0
|
|
Cobalt binding site 5 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 5 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 5 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Co301
b:23.2
occ:1.00
|
CO
|
E:B12301
|
0.0
|
23.2
|
1.0
|
|
N21
|
E:B12301
|
1.9
|
18.6
|
1.0
|
|
N22
|
E:B12301
|
1.9
|
22.9
|
1.0
|
|
N23
|
E:B12301
|
1.9
|
20.5
|
1.0
|
|
N24
|
E:B12301
|
1.9
|
20.4
|
1.0
|
|
C5'
|
F:5AD401
|
2.5
|
31.7
|
1.0
|
|
C19
|
E:B12301
|
2.7
|
18.4
|
1.0
|
|
C16
|
E:B12301
|
2.8
|
18.4
|
1.0
|
|
C1
|
E:B12301
|
2.8
|
21.2
|
1.0
|
|
C9
|
E:B12301
|
2.9
|
21.6
|
1.0
|
|
C4
|
E:B12301
|
3.0
|
21.8
|
1.0
|
|
C14
|
E:B12301
|
3.0
|
20.7
|
1.0
|
|
C11
|
E:B12301
|
3.0
|
20.9
|
1.0
|
|
C6
|
E:B12301
|
3.0
|
21.1
|
1.0
|
|
C15
|
E:B12301
|
3.3
|
20.6
|
1.0
|
|
C10
|
E:B12301
|
3.4
|
20.5
|
1.0
|
|
C5
|
E:B12301
|
3.4
|
22.6
|
1.0
|
|
C4'
|
F:5AD401
|
3.5
|
33.7
|
1.0
|
|
C20
|
E:B12301
|
3.5
|
19.3
|
1.0
|
|
O4'
|
F:5AD401
|
3.5
|
35.0
|
1.0
|
|
N52
|
E:B12301
|
3.9
|
19.6
|
1.0
|
|
C18
|
E:B12301
|
4.0
|
19.2
|
1.0
|
|
C17
|
E:B12301
|
4.0
|
21.7
|
1.0
|
|
C2
|
E:B12301
|
4.1
|
21.1
|
1.0
|
|
O44
|
E:B12301
|
4.2
|
27.6
|
1.0
|
|
C3
|
E:B12301
|
4.2
|
20.8
|
1.0
|
|
C8
|
E:B12301
|
4.2
|
23.9
|
1.0
|
|
C7
|
E:B12301
|
4.3
|
25.0
|
1.0
|
|
C13
|
E:B12301
|
4.3
|
20.5
|
1.0
|
|
C12
|
E:B12301
|
4.3
|
21.1
|
1.0
|
|
C50
|
E:B12301
|
4.5
|
24.1
|
1.0
|
|
C26
|
E:B12301
|
4.6
|
20.4
|
1.0
|
|
C49
|
E:B12301
|
4.7
|
21.2
|
1.0
|
|
C53
|
E:B12301
|
4.8
|
19.3
|
1.0
|
|
C43
|
E:B12301
|
4.8
|
30.4
|
1.0
|
|
C54
|
E:B12301
|
4.8
|
18.5
|
1.0
|
|
C3'
|
F:5AD401
|
4.8
|
34.8
|
1.0
|
|
C46
|
E:B12301
|
4.9
|
17.4
|
1.0
|
|
C1'
|
F:5AD401
|
4.9
|
33.1
|
1.0
|
|
C42
|
E:B12301
|
4.9
|
28.2
|
1.0
|
|
C35
|
E:B12301
|
4.9
|
23.7
|
1.0
|
|
C37
|
E:B12301
|
4.9
|
24.3
|
1.0
|
|
Cobalt binding site 6 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 6 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 6 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Co301
b:19.4
occ:1.00
|
CO
|
F:B12301
|
0.0
|
19.4
|
1.0
|
|
N21
|
F:B12301
|
1.9
|
15.8
|
1.0
|
|
N22
|
F:B12301
|
1.9
|
19.7
|
1.0
|
|
N23
|
F:B12301
|
1.9
|
17.6
|
1.0
|
|
N24
|
F:B12301
|
1.9
|
19.2
|
1.0
|
|
C5'
|
E:5AD401
|
2.5
|
29.8
|
1.0
|
|
C19
|
F:B12301
|
2.7
|
17.5
|
1.0
|
|
C16
|
F:B12301
|
2.8
|
17.6
|
1.0
|
|
C1
|
F:B12301
|
2.8
|
19.6
|
1.0
|
|
C9
|
F:B12301
|
2.9
|
18.7
|
1.0
|
|
C14
|
F:B12301
|
3.0
|
18.4
|
1.0
|
|
C11
|
F:B12301
|
3.0
|
18.4
|
1.0
|
|
C4
|
F:B12301
|
3.0
|
18.6
|
1.0
|
|
C6
|
F:B12301
|
3.0
|
18.3
|
1.0
|
|
C15
|
F:B12301
|
3.3
|
19.3
|
1.0
|
|
C10
|
F:B12301
|
3.4
|
18.1
|
1.0
|
|
C5
|
F:B12301
|
3.4
|
19.6
|
1.0
|
|
C4'
|
E:5AD401
|
3.4
|
32.6
|
1.0
|
|
O4'
|
E:5AD401
|
3.5
|
31.9
|
1.0
|
|
C20
|
F:B12301
|
3.5
|
18.6
|
1.0
|
|
N52
|
F:B12301
|
3.9
|
12.2
|
1.0
|
|
C17
|
F:B12301
|
4.0
|
21.6
|
1.0
|
|
C18
|
F:B12301
|
4.0
|
18.8
|
1.0
|
|
C2
|
F:B12301
|
4.1
|
19.3
|
1.0
|
|
O44
|
F:B12301
|
4.2
|
18.9
|
1.0
|
|
C8
|
F:B12301
|
4.2
|
21.5
|
1.0
|
|
C3
|
F:B12301
|
4.2
|
17.6
|
1.0
|
|
C12
|
F:B12301
|
4.3
|
19.1
|
1.0
|
|
C13
|
F:B12301
|
4.3
|
18.1
|
1.0
|
|
C7
|
F:B12301
|
4.3
|
22.6
|
1.0
|
|
C50
|
F:B12301
|
4.5
|
17.9
|
1.0
|
|
C26
|
F:B12301
|
4.6
|
19.4
|
1.0
|
|
C49
|
F:B12301
|
4.7
|
16.6
|
1.0
|
|
C43
|
F:B12301
|
4.8
|
26.7
|
1.0
|
|
C53
|
F:B12301
|
4.8
|
20.3
|
1.0
|
|
C54
|
F:B12301
|
4.8
|
19.0
|
1.0
|
|
C46
|
F:B12301
|
4.8
|
15.8
|
1.0
|
|
C3'
|
E:5AD401
|
4.8
|
37.7
|
1.0
|
|
C1'
|
E:5AD401
|
4.9
|
33.7
|
1.0
|
|
C42
|
F:B12301
|
4.9
|
24.9
|
1.0
|
|
C37
|
F:B12301
|
4.9
|
22.4
|
1.0
|
|
C35
|
F:B12301
|
4.9
|
20.8
|
1.0
|
|
Cobalt binding site 7 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 7 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 7 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Co301
b:20.0
occ:1.00
|
CO
|
G:B12301
|
0.0
|
20.0
|
1.0
|
|
N21
|
G:B12301
|
1.9
|
17.0
|
1.0
|
|
N22
|
G:B12301
|
1.9
|
19.9
|
1.0
|
|
N23
|
G:B12301
|
1.9
|
18.4
|
1.0
|
|
N24
|
G:B12301
|
1.9
|
18.5
|
1.0
|
|
C5'
|
H:5AD401
|
2.5
|
36.0
|
1.0
|
|
C19
|
G:B12301
|
2.7
|
16.3
|
1.0
|
|
C16
|
G:B12301
|
2.8
|
16.6
|
1.0
|
|
C1
|
G:B12301
|
2.8
|
19.1
|
1.0
|
|
C9
|
G:B12301
|
2.9
|
18.6
|
1.0
|
|
C14
|
G:B12301
|
3.0
|
18.4
|
1.0
|
|
C11
|
G:B12301
|
3.0
|
18.9
|
1.0
|
|
C4
|
G:B12301
|
3.0
|
19.1
|
1.0
|
|
C6
|
G:B12301
|
3.0
|
18.2
|
1.0
|
|
C15
|
G:B12301
|
3.3
|
18.3
|
1.0
|
|
C10
|
G:B12301
|
3.4
|
18.2
|
1.0
|
|
C5
|
G:B12301
|
3.4
|
19.6
|
1.0
|
|
C4'
|
H:5AD401
|
3.4
|
36.7
|
1.0
|
|
O4'
|
H:5AD401
|
3.5
|
34.9
|
1.0
|
|
C20
|
G:B12301
|
3.5
|
16.7
|
1.0
|
|
N52
|
G:B12301
|
3.9
|
19.0
|
1.0
|
|
C17
|
G:B12301
|
4.0
|
20.4
|
1.0
|
|
C18
|
G:B12301
|
4.1
|
17.3
|
1.0
|
|
C2
|
G:B12301
|
4.1
|
19.9
|
1.0
|
|
O44
|
G:B12301
|
4.2
|
23.8
|
1.0
|
|
C8
|
G:B12301
|
4.2
|
20.6
|
1.0
|
|
C3
|
G:B12301
|
4.2
|
18.1
|
1.0
|
|
C13
|
G:B12301
|
4.3
|
18.2
|
1.0
|
|
C12
|
G:B12301
|
4.3
|
19.3
|
1.0
|
|
C7
|
G:B12301
|
4.3
|
21.9
|
1.0
|
|
C50
|
G:B12301
|
4.5
|
22.3
|
1.0
|
|
C26
|
G:B12301
|
4.6
|
20.8
|
1.0
|
|
C49
|
G:B12301
|
4.7
|
18.8
|
1.0
|
|
C43
|
G:B12301
|
4.8
|
26.7
|
1.0
|
|
C53
|
G:B12301
|
4.8
|
16.2
|
1.0
|
|
C54
|
G:B12301
|
4.8
|
17.5
|
1.0
|
|
C46
|
G:B12301
|
4.8
|
15.7
|
1.0
|
|
C3'
|
H:5AD401
|
4.8
|
37.4
|
1.0
|
|
C42
|
G:B12301
|
4.9
|
23.4
|
1.0
|
|
C1'
|
H:5AD401
|
4.9
|
33.4
|
1.0
|
|
C37
|
G:B12301
|
4.9
|
21.1
|
1.0
|
|
C35
|
G:B12301
|
4.9
|
20.8
|
1.0
|
|
Cobalt binding site 8 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 8 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 8 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Co301
b:20.2
occ:1.00
|
CO
|
H:B12301
|
0.0
|
20.2
|
1.0
|
|
N21
|
H:B12301
|
1.9
|
17.1
|
1.0
|
|
N22
|
H:B12301
|
1.9
|
21.3
|
1.0
|
|
N23
|
H:B12301
|
1.9
|
18.9
|
1.0
|
|
N24
|
H:B12301
|
2.0
|
18.4
|
1.0
|
|
C5'
|
G:5AD401
|
2.5
|
33.1
|
1.0
|
|
C19
|
H:B12301
|
2.7
|
16.3
|
1.0
|
|
C16
|
H:B12301
|
2.8
|
16.3
|
1.0
|
|
C1
|
H:B12301
|
2.8
|
19.1
|
1.0
|
|
C9
|
H:B12301
|
2.9
|
20.1
|
1.0
|
|
C14
|
H:B12301
|
3.0
|
19.0
|
1.0
|
|
C11
|
H:B12301
|
3.0
|
19.9
|
1.0
|
|
C4
|
H:B12301
|
3.0
|
20.2
|
1.0
|
|
C6
|
H:B12301
|
3.0
|
19.8
|
1.0
|
|
C15
|
H:B12301
|
3.3
|
18.7
|
1.0
|
|
C10
|
H:B12301
|
3.3
|
19.4
|
1.0
|
|
C5
|
H:B12301
|
3.4
|
21.4
|
1.0
|
|
C4'
|
G:5AD401
|
3.4
|
35.8
|
1.0
|
|
O4'
|
G:5AD401
|
3.5
|
35.6
|
1.0
|
|
C20
|
H:B12301
|
3.5
|
16.8
|
1.0
|
|
N52
|
H:B12301
|
3.9
|
20.3
|
1.0
|
|
C17
|
H:B12301
|
4.1
|
19.8
|
1.0
|
|
C18
|
H:B12301
|
4.1
|
17.0
|
1.0
|
|
C2
|
H:B12301
|
4.1
|
19.5
|
1.0
|
|
O44
|
H:B12301
|
4.2
|
26.6
|
1.0
|
|
C8
|
H:B12301
|
4.2
|
22.3
|
1.0
|
|
C3
|
H:B12301
|
4.2
|
18.9
|
1.0
|
|
C13
|
H:B12301
|
4.2
|
19.4
|
1.0
|
|
C12
|
H:B12301
|
4.2
|
20.2
|
1.0
|
|
C7
|
H:B12301
|
4.3
|
23.6
|
1.0
|
|
C50
|
H:B12301
|
4.5
|
23.9
|
1.0
|
|
C26
|
H:B12301
|
4.6
|
19.9
|
1.0
|
|
C49
|
H:B12301
|
4.7
|
21.0
|
1.0
|
|
C53
|
H:B12301
|
4.8
|
17.5
|
1.0
|
|
C43
|
H:B12301
|
4.8
|
29.7
|
1.0
|
|
C46
|
H:B12301
|
4.8
|
16.7
|
1.0
|
|
C54
|
H:B12301
|
4.8
|
16.5
|
1.0
|
|
C3'
|
G:5AD401
|
4.9
|
38.5
|
1.0
|
|
C1'
|
G:5AD401
|
4.9
|
34.2
|
1.0
|
|
C42
|
H:B12301
|
4.9
|
26.8
|
1.0
|
|
C37
|
H:B12301
|
4.9
|
23.1
|
1.0
|
|
C35
|
H:B12301
|
4.9
|
22.4
|
1.0
|
|
Cobalt binding site 9 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 9 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 9 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Co301
b:21.3
occ:1.00
|
CO
|
I:B12301
|
0.0
|
21.3
|
1.0
|
|
N21
|
I:B12301
|
1.9
|
18.9
|
1.0
|
|
N22
|
I:B12301
|
1.9
|
22.5
|
1.0
|
|
N23
|
I:B12301
|
1.9
|
22.3
|
1.0
|
|
N24
|
I:B12301
|
2.0
|
21.1
|
1.0
|
|
C5'
|
J:5AD401
|
2.5
|
35.9
|
1.0
|
|
C19
|
I:B12301
|
2.7
|
18.9
|
1.0
|
|
C16
|
I:B12301
|
2.8
|
19.6
|
1.0
|
|
C1
|
I:B12301
|
2.8
|
21.3
|
1.0
|
|
C9
|
I:B12301
|
2.9
|
21.4
|
1.0
|
|
C14
|
I:B12301
|
3.0
|
22.8
|
1.0
|
|
C11
|
I:B12301
|
3.0
|
22.9
|
1.0
|
|
C4
|
I:B12301
|
3.0
|
21.1
|
1.0
|
|
C6
|
I:B12301
|
3.0
|
20.9
|
1.0
|
|
C15
|
I:B12301
|
3.3
|
22.3
|
1.0
|
|
C10
|
I:B12301
|
3.4
|
21.7
|
1.0
|
|
C5
|
I:B12301
|
3.4
|
22.0
|
1.0
|
|
C4'
|
J:5AD401
|
3.4
|
36.4
|
1.0
|
|
O4'
|
J:5AD401
|
3.5
|
35.7
|
1.0
|
|
C20
|
I:B12301
|
3.5
|
19.8
|
1.0
|
|
N52
|
I:B12301
|
3.9
|
20.5
|
1.0
|
|
C17
|
I:B12301
|
4.1
|
23.4
|
1.0
|
|
C18
|
I:B12301
|
4.1
|
20.2
|
1.0
|
|
C2
|
I:B12301
|
4.1
|
20.9
|
1.0
|
|
C8
|
I:B12301
|
4.2
|
24.1
|
1.0
|
|
O44
|
I:B12301
|
4.2
|
28.9
|
1.0
|
|
C3
|
I:B12301
|
4.2
|
19.9
|
1.0
|
|
C7
|
I:B12301
|
4.3
|
24.7
|
1.0
|
|
C12
|
I:B12301
|
4.3
|
23.9
|
1.0
|
|
C13
|
I:B12301
|
4.3
|
23.0
|
1.0
|
|
C50
|
I:B12301
|
4.5
|
26.0
|
1.0
|
|
C26
|
I:B12301
|
4.6
|
20.7
|
1.0
|
|
C49
|
I:B12301
|
4.7
|
23.4
|
1.0
|
|
C53
|
I:B12301
|
4.8
|
21.0
|
1.0
|
|
C43
|
I:B12301
|
4.8
|
33.2
|
1.0
|
|
C54
|
I:B12301
|
4.8
|
20.7
|
1.0
|
|
C3'
|
J:5AD401
|
4.8
|
37.4
|
1.0
|
|
C46
|
I:B12301
|
4.8
|
20.5
|
1.0
|
|
C1'
|
J:5AD401
|
4.9
|
32.8
|
1.0
|
|
C37
|
I:B12301
|
4.9
|
23.8
|
1.0
|
|
C42
|
I:B12301
|
4.9
|
29.8
|
1.0
|
|
C35
|
I:B12301
|
4.9
|
23.4
|
1.0
|
|
Cobalt binding site 10 out
of 16 in 3som
Go back to
Cobalt Binding Sites List in 3som
Cobalt binding site 10 out
of 16 in the Crystal Structure of Human Mmachc
 Mono view
 Stereo pair view
|
|
A full contact list of Cobalt with other atoms in the Co binding
site number 10 of Crystal Structure of Human Mmachc within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Co301
b:22.4
occ:1.00
|
CO
|
J:B12301
|
0.0
|
22.4
|
1.0
|
|
N21
|
J:B12301
|
1.9
|
19.1
|
1.0
|
|
N22
|
J:B12301
|
1.9
|
23.0
|
1.0
|
|
N23
|
J:B12301
|
1.9
|
21.7
|
1.0
|
|
N24
|
J:B12301
|
2.0
|
20.9
|
1.0
|
|
C5'
|
I:5AD401
|
2.5
|
35.6
|
1.0
|
|
C19
|
J:B12301
|
2.7
|
18.4
|
1.0
|
|
C1
|
J:B12301
|
2.8
|
21.6
|
1.0
|
|
C16
|
J:B12301
|
2.8
|
18.6
|
1.0
|
|
C9
|
J:B12301
|
2.9
|
21.7
|
1.0
|
|
C4
|
J:B12301
|
3.0
|
21.9
|
1.0
|
|
C14
|
J:B12301
|
3.0
|
21.6
|
1.0
|
|
C11
|
J:B12301
|
3.0
|
22.8
|
1.0
|
|
C6
|
J:B12301
|
3.0
|
21.1
|
1.0
|
|
C15
|
J:B12301
|
3.3
|
21.3
|
1.0
|
|
C10
|
J:B12301
|
3.4
|
22.2
|
1.0
|
|
C5
|
J:B12301
|
3.4
|
22.7
|
1.0
|
|
C4'
|
I:5AD401
|
3.4
|
36.4
|
1.0
|
|
O4'
|
I:5AD401
|
3.5
|
35.1
|
1.0
|
|
C20
|
J:B12301
|
3.5
|
19.3
|
1.0
|
|
N52
|
J:B12301
|
3.9
|
19.4
|
1.0
|
|
C18
|
J:B12301
|
4.0
|
19.2
|
1.0
|
|
C17
|
J:B12301
|
4.1
|
22.3
|
1.0
|
|
C2
|
J:B12301
|
4.1
|
21.7
|
1.0
|
|
O44
|
J:B12301
|
4.2
|
30.2
|
1.0
|
|
C8
|
J:B12301
|
4.2
|
23.8
|
1.0
|
|
C3
|
J:B12301
|
4.2
|
21.1
|
1.0
|
|
C7
|
J:B12301
|
4.3
|
24.3
|
1.0
|
|
C12
|
J:B12301
|
4.3
|
23.2
|
1.0
|
|
C13
|
J:B12301
|
4.3
|
21.7
|
1.0
|
|
C50
|
J:B12301
|
4.5
|
23.5
|
1.0
|
|
C26
|
J:B12301
|
4.6
|
22.0
|
1.0
|
|
C49
|
J:B12301
|
4.7
|
21.4
|
1.0
|
|
C43
|
J:B12301
|
4.8
|
31.4
|
1.0
|
|
C53
|
J:B12301
|
4.8
|
20.1
|
1.0
|
|
C54
|
J:B12301
|
4.8
|
19.0
|
1.0
|
|
C46
|
J:B12301
|
4.8
|
19.8
|
1.0
|
|
C3'
|
I:5AD401
|
4.9
|
35.7
|
1.0
|
|
C42
|
J:B12301
|
4.9
|
27.3
|
1.0
|
|
C1'
|
I:5AD401
|
4.9
|
32.5
|
1.0
|
|
C37
|
J:B12301
|
4.9
|
23.9
|
1.0
|
|
C35
|
J:B12301
|
4.9
|
23.9
|
1.0
|
|
Reference:
D.S.Froese,
T.Krojer,
X.Wu,
R.Shrestha,
W.Kiyani,
F.Von Delft,
R.A.Gravel,
U.Oppermann,
W.W.Yue.
Structure of Mmachc Reveals An Arginine-Rich Pocket and A Domain-Swapped Dimer For Its B12 Processing Function. Biochemistry V. 51 5083 2012.
ISSN: ISSN 0006-2960
PubMed: 22642810
DOI: 10.1021/BI300150Y
Page generated: Tue Jul 30 16:34:54 2024
|
