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Cobalt in PDB 3w1a: Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives

Enzymatic activity of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives

All present enzymatic activity of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives:
1.3.98.1;

Protein crystallography data

The structure of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives, PDB code: 3w1a was solved by D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Matsuoka, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka, S.Harada, K.Kita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.89 / 1.42
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.240, 71.819, 123.775, 90.00, 90.00, 90.00
R / Rfree (%) 15 / 17.9

Other elements in 3w1a:

The structure of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives (pdb code 3w1a). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives, PDB code: 3w1a:

Cobalt binding site 1 out of 1 in 3w1a

Go back to Cobalt Binding Sites List in 3w1a
Cobalt binding site 1 out of 1 in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co402

b:10.2
occ:1.00
CO A:NCO402 0.0 10.2 1.0
N2 A:NCO402 2.0 11.7 1.0
N6 A:NCO402 2.0 12.8 1.0
N4 A:NCO402 2.0 11.8 1.0
N3 A:NCO402 2.0 11.9 1.0
N1 A:NCO402 2.0 12.8 1.0
N5 A:NCO402 2.1 12.5 1.0
O A:GLN275 3.8 8.6 1.0
O A:HOH839 3.9 20.2 1.0
O A:GLU276 4.1 8.8 1.0
O A:HOH683 4.2 22.4 1.0
O A:HOH851 4.2 21.1 1.0
O A:HOH882 4.3 25.9 1.0
O A:HOH873 4.3 26.9 1.0
O A:HOH561 4.4 17.8 1.0
C A:GLU276 4.8 8.4 1.0
C A:GLN275 5.0 7.6 1.0

Reference:

D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Matsuoka, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka, S.Harada, K.Kita. Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Halogenated Orotate Derivatives To Be Published.
Page generated: Sun Dec 13 10:42:56 2020

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