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Cobalt in PDB 3w1m: Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate

Enzymatic activity of Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate

All present enzymatic activity of Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate:
1.3.98.1;

Protein crystallography data

The structure of Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate, PDB code: 3w1m was solved by D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Matsuoka, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.95 / 1.90
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.341, 71.912, 123.849, 90.00, 90.00, 90.00
R / Rfree (%) 14.3 / 18.3

Other elements in 3w1m:

The structure of Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate also contains other interesting chemical elements:

Bromine (Br) 2 atoms

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate (pdb code 3w1m). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate, PDB code: 3w1m:

Cobalt binding site 1 out of 1 in 3w1m

Go back to Cobalt Binding Sites List in 3w1m
Cobalt binding site 1 out of 1 in the Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co402

b:6.3
occ:1.00
CO A:NCO402 0.0 6.3 1.0
N3 A:NCO402 2.0 6.5 1.0
N5 A:NCO402 2.0 6.4 1.0
N4 A:NCO402 2.0 6.5 1.0
N6 A:NCO402 2.0 5.8 1.0
N2 A:NCO402 2.0 6.3 1.0
N1 A:NCO402 2.0 6.7 1.0
O A:GLN275 3.8 4.7 1.0
O A:HOH777 3.9 15.7 1.0
O A:GLU276 4.2 5.0 1.0
O A:HOH804 4.3 23.7 1.0
O A:HOH680 4.3 20.7 1.0
O A:HOH564 4.3 11.8 1.0
O A:HOH789 4.3 22.0 1.0
O A:HOH811 4.4 23.2 1.0
C A:GLU276 4.9 4.9 1.0

Reference:

D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Matsuoka, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka. Crystal Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with 5-Bromoorotate To Be Published.
Page generated: Tue Jul 30 16:49:13 2024

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