Cobalt in PDB 3w85: Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139

All present enzymatic activity of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139:
1.3.98.1;

The structure of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139, PDB code: 3w85 was solved by D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Hashimoto, S.Matsuoka, T.Kuranaga, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka, S.Harada, K.Kita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.97 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.259, 72.060, 129.440, 90.00, 90.00, 90.00
R / Rfree (%)	15.4 / 20.2

The binding sites of Cobalt atom in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139 (pdb code 3w85). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139, PDB code: 3w85:

Cobalt binding site 1 out of 1 in the Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co411 b:14.6 occ:1.00 CO A:NCO411 0.0 14.6 1.0 N3 A:NCO411 1.9 15.7 1.0 N5 A:NCO411 2.0 14.8 1.0 N2 A:NCO411 2.0 14.8 1.0 N4 A:NCO411 2.0 13.5 1.0 N6 A:NCO411 2.0 14.8 1.0 N1 A:NCO411 2.1 12.0 1.0 O A:GLN275 3.9 12.6 1.0 O A:HOH708 4.0 26.2 1.0 O A:GLU276 4.3 10.4 1.0 O A:HOH554 4.5 25.4 1.0 O A:HOH678 4.5 43.0 1.0 C A:GLU276 5.0 11.3 1.0

D.K.Inaoka, M.Iida, T.Tabuchi, N.Lee, S.Hashimoto, S.Matsuoka, T.Kuranaga, T.Shiba, K.Sakamoto, S.Suzuki, E.O.Balogun, T.Nara, T.Aoki, M.Inoue, T.Honma, A.Tanaka, S.Harada, K.Kita. Structure of Trypanosoma Cruzi Dihydroorotate Dehydrogenase in Complex with TT2-3-139 To Be Published.