Cobalt in PDB 4bqt: Aplysia Californica Achbp in Complex with Cytisine

The structure of Aplysia Californica Achbp in Complex with Cytisine, PDB code: 4bqt was solved by P.Rucktooa, C.A.Haseler, R.Vanelke, A.B.Smit, T.Gallagher, T.K.Sixma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.72 / 2.88
Space group	I 2 3 1
Cell size a, b, c (Å), α, β, γ (°)	206.689, 206.689, 206.689, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.4

The structure of Aplysia Californica Achbp in Complex with Cytisine also contains other interesting chemical elements:

Chlorine

(Cl)

11 atoms

The binding sites of Cobalt atom in the Aplysia Californica Achbp in Complex with Cytisine (pdb code 4bqt). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Aplysia Californica Achbp in Complex with Cytisine, PDB code: 4bqt:

Cobalt binding site 1 out of 1 in the Aplysia Californica Achbp in Complex with Cytisine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Aplysia Californica Achbp in Complex with Cytisine within 5.0Å range: probe atom residue distance (Å) B Occ B:Co311 b:49.1 occ:1.00 CG1 B:VAL183 3.6 51.3 1.0 NE2 B:HIS185 3.7 47.8 1.0 CB B:VAL183 4.0 49.3 1.0 CE1 B:HIS185 4.1 50.4 1.0 CG2 B:VAL183 4.5 50.9 1.0

P.Rucktooa, C.A.Haseler, R.Van Elk, A.B.Smit, T.Gallagher, T.K.Sixma. Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors Through Study of Ligand Complexes with Acetylcholine-Binding Protein. J.Biol.Chem. V. 287 23283 2012.
ISSN: ISSN 0021-9258
PubMed: 22553201
DOI: 10.1074/JBC.M112.360347