Atomistry » Cobalt » PDB 4as7-4fck » 4ekd
Atomistry »
  Cobalt »
    PDB 4as7-4fck »
      4ekd »

Cobalt in PDB 4ekd: Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C)

Enzymatic activity of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C)

All present enzymatic activity of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C):
3.6.5.1;

Protein crystallography data

The structure of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C), PDB code: 4ekd was solved by J.J.G.Tesmer, M.R.Nance, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.98 / 2.71
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 60.248, 60.248, 345.569, 90.00, 90.00, 90.00
R / Rfree (%) 19 / 25.2

Other elements in 4ekd:

The structure of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C) also contains other interesting chemical elements:

Fluorine (F) 4 atoms
Magnesium (Mg) 1 atom
Aluminium (Al) 1 atom
Chlorine (Cl) 2 atoms

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C) (pdb code 4ekd). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C), PDB code: 4ekd:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in 4ekd

Go back to Cobalt Binding Sites List in 4ekd
Cobalt binding site 1 out of 2 in the Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C)


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co403

b:95.1
occ:1.00
NE2 A:HIS105 1.8 0.6 1.0
CL A:CL404 2.5 0.7 1.0
CL A:CL405 2.5 96.6 1.0
NE2 A:HIS109 2.5 0.1 1.0
CD2 A:HIS105 2.7 99.4 1.0
CE1 A:HIS105 2.9 0.7 1.0
CD2 A:HIS109 3.2 0.6 1.0
CE1 A:HIS109 3.7 0.3 1.0
CG A:HIS105 3.9 0.1 1.0
ND1 A:HIS105 4.0 0.1 1.0
CG A:HIS109 4.5 0.1 1.0
ND1 A:HIS109 4.7 0.9 1.0

Cobalt binding site 2 out of 2 in 4ekd

Go back to Cobalt Binding Sites List in 4ekd
Cobalt binding site 2 out of 2 in the Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C)


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Structure of Human Regulator of G Protein Signaling 2 (RGS2) in Complex with Murine Galpha-Q(R183C) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co406

b:0.2
occ:1.00
OD1 A:ASP321 2.1 0.6 1.0
OD1 A:ASP319 2.1 0.0 1.0
CG A:ASP319 2.9 0.1 1.0
CG A:ASP321 2.9 0.1 1.0
OD2 A:ASP319 3.0 0.1 1.0
OD2 A:ASP321 3.1 0.4 1.0
CB A:ASP321 4.4 0.3 1.0
CB A:ASP319 4.4 0.3 1.0
N A:ASP321 4.8 0.3 1.0
CA A:ASP319 4.9 0.7 1.0

Reference:

M.R.Nance, B.Kreutz, V.M.Tesmer, R.Sterne-Marr, T.Kozasa, J.J.Tesmer. Structural and Functional Analysis of the Regulator of G Protein Signaling 2-G Alpha Q Complex. Structure V. 21 438 2013.
ISSN: ISSN 0969-2126
PubMed: 23434405
DOI: 10.1016/J.STR.2012.12.016
Page generated: Sun Dec 13 10:44:09 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy