Cobalt in PDB 4gpr: Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica

The structure of Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica, PDB code: 4gpr was solved by D.E.Bosch, D.P.Siderovski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.07 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.973, 49.577, 63.464, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 20.2

The binding sites of Cobalt atom in the Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica (pdb code 4gpr). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica, PDB code: 4gpr:

Cobalt binding site 1 out of 1 in the Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of EHUBC5, A Ubiquitin Conjugating Enzyme From Entamoeba Histolytica within 5.0Å range: probe atom residue distance (Å) B Occ A:Co201 b:8.1 occ:1.00 NE2 A:HIS32 2.1 9.6 1.0 O A:HOH305 2.1 7.8 1.0 NE2 A:HIS55 2.2 7.9 1.0 OD1 A:ASP53 2.2 6.2 1.0 OD2 A:ASP53 2.2 6.8 1.0 CG A:ASP53 2.5 6.3 1.0 CE1 A:HIS55 3.1 17.8 1.0 CD2 A:HIS32 3.1 9.2 1.0 CE1 A:HIS32 3.1 8.1 1.0 CD2 A:HIS55 3.1 7.3 1.0 CB A:ASP53 4.0 5.8 1.0 O A:HOH416 4.1 27.3 1.0 ND1 A:HIS55 4.2 15.2 1.0 ND1 A:HIS32 4.2 9.0 1.0 CG A:HIS32 4.2 7.5 1.0 CG A:HIS55 4.2 7.3 1.0 CA A:ASP53 4.8 5.2 1.0

D.E.Bosch, D.P.Siderovski. Structural Determinants of Ubiquitin Conjugation in Entamoeba Histolytica. J.Biol.Chem. V. 288 2290 2013.
ISSN: ISSN 0021-9258
PubMed: 23209297
DOI: 10.1074/JBC.M112.417337