Atomistry » Cobalt » PDB 4fe5-4j0b » 4iec
Atomistry »
  Cobalt »
    PDB 4fe5-4j0b »
      4iec »

Cobalt in PDB 4iec: CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C

Enzymatic activity of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C

All present enzymatic activity of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C:
3.4.11.18;

Protein crystallography data

The structure of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C, PDB code: 4iec was solved by R.Reddi, R.Gumpena, C.Kishor, A.Addlagatta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.82 / 2.00
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 49.330, 48.241, 56.653, 90.00, 95.17, 90.00
R / Rfree (%) 16.6 / 23.6

Other elements in 4iec:

The structure of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C also contains other interesting chemical elements:

Potassium (K) 1 atom

Cobalt Binding Sites:

The binding sites of Cobalt atom in the CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (pdb code 4iec). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C, PDB code: 4iec:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in 4iec

Go back to Cobalt Binding Sites List in 4iec
Cobalt binding site 1 out of 2 in the CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co401

b:5.0
occ:1.00
 O A:HOH534 2.0 7.2 1.0
NE2 A:HIS205 2.0 2.0 1.0
OE1 A:GLU269 2.1 3.3 1.0
OD1 A:ASP142 2.1 5.9 1.0
OE2 A:GLU238 2.2 5.5 1.0
CE1 A:HIS205 3.0 3.6 1.0
CD2 A:HIS205 3.0 3.7 1.0
CG A:ASP142 3.0 3.2 1.0
CD A:GLU269 3.0 3.2 1.0
CD A:GLU238 3.1 4.4 1.0
CO A:CO402 3.2 5.7 1.0
OE2 A:GLU269 3.3 4.6 1.0
OE1 A:GLU238 3.3 8.6 1.0
OD2 A:ASP142 3.4 2.0 1.0
OG1 A:THR236 3.6 3.1 1.0
CG2 A:THR236 3.7 5.0 1.0
CB A:THR236 4.0 4.4 1.0
ND1 A:HIS205 4.1 4.0 1.0
CG A:HIS205 4.1 4.5 1.0
O A:HOH509 4.2 13.2 1.0
CB A:ASP142 4.2 3.5 1.0
CG A:GLU269 4.3 2.6 1.0
CG A:GLU238 4.4 5.1 1.0
NE2 A:HIS212 4.7 10.0 1.0
OD2 A:ASP131 4.9 6.8 1.0
CB A:GLU238 4.9 2.7 1.0

Cobalt binding site 2 out of 2 in 4iec

Go back to Cobalt Binding Sites List in 4iec
Cobalt binding site 2 out of 2 in the CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co402

b:5.7
occ:1.00
 O A:HOH534 2.0 7.2 1.0
OE2 A:GLU269 2.1 4.6 1.0
OD2 A:ASP142 2.1 2.0 1.0
OD1 A:ASP131 2.1 6.8 1.0
OD2 A:ASP131 2.2 6.8 1.0
O A:HOH509 2.3 13.2 1.0
CG A:ASP131 2.5 6.1 1.0
CG A:ASP142 3.0 3.2 1.0
CD A:GLU269 3.0 3.2 1.0
OD1 A:ASP142 3.1 5.9 1.0
CO A:CO401 3.2 5.0 1.0
OE1 A:GLU269 3.3 3.3 1.0
CB A:ASP131 4.0 4.1 1.0
OG1 A:THR133 4.2 7.3 1.0
OE1 A:GLU238 4.2 8.6 1.0
ND2 A:ASN144 4.3 3.4 1.0
CE A:CME105 4.4 25.3 1.0
CG A:GLU269 4.4 2.6 1.0
CB A:ASP142 4.4 3.5 1.0
N A:THR143 4.5 6.8 1.0
O A:THR143 4.5 8.1 1.0
O A:HOH512 4.6 5.4 1.0
OE2 A:GLU238 4.6 5.5 1.0
CB A:ASN144 4.7 5.3 1.0
CD A:GLU238 4.7 4.4 1.0
C A:ASP142 4.8 4.5 1.0
C A:THR143 4.8 7.1 1.0
CA A:ASP131 4.8 8.3 1.0
CB A:GLU269 4.9 2.0 1.0
N A:VAL132 4.9 7.5 0.5
CA A:ASP142 4.9 3.8 1.0
NE2 A:HIS205 5.0 2.0 1.0

Reference:

R.Reddi, R.Gumpena, C.Kishor, A.Addlagatta. CYS105 Covalent Modification By 2-Hydroxyethyl Disulfide in Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C To Be Published.
Page generated: Sun Dec 13 10:44:34 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy