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Atomistry » Cobalt » PDB 4fe5-4j0b » 4iu6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Cobalt » PDB 4fe5-4j0b » 4iu6 » |
Cobalt in PDB 4iu6: Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1Enzymatic activity of Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
All present enzymatic activity of Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1:
3.4.11.18; Protein crystallography data
The structure of Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1, PDB code: 4iu6
was solved by
S.B.Gabelli,
F.Zhang,
M.Miller,
J.Liu,
L.M.Amzel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4iu6:
The structure of Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 also contains other interesting chemical elements:
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
(pdb code 4iu6). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 3 binding sites of Cobalt where determined in the Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1, PDB code: 4iu6: Jump to Cobalt binding site number: 1; 2; 3; Cobalt binding site 1 out of 3 in 4iu6Go back to Cobalt Binding Sites List in 4iu6
Cobalt binding site 1 out
of 3 in the Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Mono view Stereo pair view
Cobalt binding site 2 out of 3 in 4iu6Go back to Cobalt Binding Sites List in 4iu6
Cobalt binding site 2 out
of 3 in the Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Mono view Stereo pair view
Cobalt binding site 3 out of 3 in 4iu6Go back to Cobalt Binding Sites List in 4iu6
Cobalt binding site 3 out
of 3 in the Human Methionine Aminopeptidase in Complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Mono view Stereo pair view
Reference:
F.Zhang,
S.Bhat,
S.B.Gabelli,
X.Chen,
M.S.Miller,
B.A.Nacev,
Y.L.Cheng,
D.J.Meyers,
K.Tenney,
J.S.Shim,
P.Crews,
L.M.Amzel,
D.Ma,
J.O.Liu.
Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 in Cells. J.Med.Chem. V. 56 3996 2013.
Page generated: Tue Jul 30 17:11:47 2024
ISSN: ISSN 0022-2623 PubMed: 23634668 DOI: 10.1021/JM400227Z |
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