Cobalt in PDB 4rxw: Crystal Structure of the Cobalt Human Insulin Derivative

The structure of Crystal Structure of the Cobalt Human Insulin Derivative, PDB code: 4rxw was solved by B.Prugovecki, N.Ivetic, D.Matkovic-Calogovic, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.73
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	81.430, 81.430, 33.750, 90.00, 90.00, 120.00
R / Rfree (%)	14.3 / 20.6

The binding sites of Cobalt atom in the Crystal Structure of the Cobalt Human Insulin Derivative (pdb code 4rxw). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of the Cobalt Human Insulin Derivative, PDB code: 4rxw:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of the Cobalt Human Insulin Derivative


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of the Cobalt Human Insulin Derivative within 5.0Å range: probe atom residue distance (Å) B Occ B:Co101 b:10.4 occ:0.33 O B:HOH207 2.1 18.2 1.0 NE2 B:HIS10 2.2 9.4 1.0 CE1 B:HIS10 3.2 11.9 1.0 CD2 B:HIS10 3.2 10.2 1.0 O B:HOH210 3.2 36.4 0.3 O B:HOH236 4.2 29.5 1.0 ND1 B:HIS10 4.3 12.5 1.0 CG B:HIS10 4.3 10.6 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of the Cobalt Human Insulin Derivative


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of the Cobalt Human Insulin Derivative within 5.0Å range: probe atom residue distance (Å) B Occ D:Co101 b:12.9 occ:0.33 NE2 D:HIS10 2.2 10.6 1.0 O D:HOH208 2.4 16.7 1.0 CD2 D:HIS10 3.1 11.2 1.0 CE1 D:HIS10 3.1 12.8 1.0 O D:HOH213 3.4 37.9 0.3 ND1 D:HIS10 4.2 11.7 1.0 CG D:HIS10 4.3 10.9 1.0 O D:HOH211 4.6 37.4 1.0 O D:HOH202 4.7 19.9 1.0

B.Prugovecki, N.Ivetic, D.Matkovic-Calogovic. Crystal Structure of the Cobalt Human Insulin Derivative To Be Published.