Cobalt in PDB 4uuj: Potassium Channel Kcsa-Fab with Tetrahexylammonium

The structure of Potassium Channel Kcsa-Fab with Tetrahexylammonium, PDB code: 4uuj was solved by M.J.Lenaeus, D.Burdette, T.Wagner, P.J.Focia, A.Gross, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.64 / 2.40
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	154.615, 154.615, 75.953, 90.00, 90.00, 90.00
R / Rfree (%)	19.148 / 24.823

The structure of Potassium Channel Kcsa-Fab with Tetrahexylammonium also contains other interesting chemical elements:

Potassium

(K)

4 atoms

The binding sites of Cobalt atom in the Potassium Channel Kcsa-Fab with Tetrahexylammonium (pdb code 4uuj). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Potassium Channel Kcsa-Fab with Tetrahexylammonium, PDB code: 4uuj:

Cobalt binding site 1 out of 1 in the Potassium Channel Kcsa-Fab with Tetrahexylammonium


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Potassium Channel Kcsa-Fab with Tetrahexylammonium within 5.0Å range: probe atom residue distance (Å) B Occ C:Co1130 b:51.5 occ:0.25 NE2 C:HIS124 2.3 72.8 1.0 CE1 C:HIS124 2.9 76.8 1.0 CD2 C:HIS124 3.5 72.9 1.0 ND1 C:HIS124 4.1 81.5 1.0 CG C:HIS124 4.5 76.0 1.0

M.J.Lenaeus, D.Burdette, T.Wagner, P.J.Focia, A.Gross. Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal A Hydrophobic Binding Site. Biochemistry V. 53 5365 2014.
ISSN: ISSN 0006-2960
PubMed: 25093676
DOI: 10.1021/BI500525S