Cobalt in PDB 5n78: Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine

The structure of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine, PDB code: 5n78 was solved by M.Lerche, H.Sandhu, L.Flockner, M.Hogbom, M.Rapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.44 / 2.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	73.721, 117.316, 91.858, 90.00, 103.14, 90.00
R / Rfree (%)	17.8 / 21.8

The structure of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine also contains other interesting chemical elements:

Magnesium

(Mg)

6 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Cobalt atom in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine (pdb code 5n78). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 14 binding sites of Cobalt where determined in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine, PDB code: 5n78:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Cobalt binding site 1 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ A:Co303 b:0.9 occ:1.00 CO A:NCO303 0.0 0.9 1.0 N5 A:NCO303 2.0 0.5 1.0 N2 A:NCO303 2.0 0.6 1.0 N4 A:NCO303 2.0 0.3 1.0 N6 A:NCO303 2.0 0.1 1.0 N1 A:NCO303 2.0 0.4 1.0 N3 A:NCO303 2.0 0.5 1.0 OD1 A:ASN150 4.0 59.5 1.0 OE1 A:GLU149 4.5 72.3 1.0 OD2 A:ASP146 4.9 94.7 1.0 OD1 A:ASP146 4.9 84.3 1.0

Cobalt binding site 2 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ A:Co304 b:0.4 occ:1.00 CO A:NCO304 0.0 0.4 1.0 N4 A:NCO304 2.0 0.1 1.0 N6 A:NCO304 2.0 0.3 1.0 N2 A:NCO304 2.0 0.9 1.0 N3 A:NCO304 2.0 0.5 1.0 N1 A:NCO304 2.0 0.2 1.0 N5 A:NCO304 2.0 0.2 1.0 OE1 A:GLU147 4.3 98.7 1.0 OE1 A:GLU81 4.5 0.8 1.0 OE2 A:GLU81 4.6 0.2 1.0 OE2 A:GLU147 4.7 91.8 1.0 CD A:GLU81 4.7 0.5 1.0 CD A:GLU147 4.9 83.8 1.0

Cobalt binding site 3 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ A:Co305 b:0.2 occ:1.00 CO A:NCO305 0.0 0.2 1.0 N3 A:NCO305 2.0 0.2 1.0 N6 A:NCO305 2.0 0.7 1.0 N5 A:NCO305 2.0 0.4 1.0 N1 A:NCO305 2.0 0.6 1.0 N4 A:NCO305 2.0 0.2 1.0 N2 A:NCO305 2.0 0.8 1.0 OE1 A:GLU55 3.9 0.7 1.0 OE2 A:GLU55 4.5 84.5 1.0 CD A:GLU55 4.6 88.7 1.0

Cobalt binding site 4 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ B:Co303 b:91.8 occ:1.00 CO B:NCO303 0.0 91.8 1.0 N4 B:NCO303 2.0 88.0 1.0 N5 B:NCO303 2.0 87.3 1.0 N2 B:NCO303 2.0 90.2 1.0 N1 B:NCO303 2.0 82.0 1.0 N6 B:NCO303 2.0 90.2 1.0 N3 B:NCO303 2.0 88.2 1.0 O B:HOH403 3.7 82.5 1.0 OE1 B:GLN252 4.0 92.8 1.0 OE1 A:GLN252 4.1 83.7 1.0 OE1 E:GLN252 4.2 78.2 1.0 OE1 C:GLN252 4.2 84.8 1.0 OE1 D:GLN252 4.3 73.3 1.0 ND2 B:ASN249 4.4 81.7 1.0 ND2 A:ASN249 4.4 73.9 1.0 ND2 C:ASN249 4.7 85.2 1.0 ND2 E:ASN249 4.8 81.1 1.0 OD1 B:ASN249 4.8 91.4 1.0 CD B:GLN252 4.8 78.0 1.0 CG B:ASN249 4.9 79.1 1.0 OD1 A:ASN249 4.9 83.5 1.0 CD A:GLN252 4.9 83.1 1.0 CG A:ASN249 4.9 73.1 1.0 NE2 A:GLN252 4.9 87.9 1.0 NE2 B:GLN252 4.9 78.8 1.0 OD1 E:ASN249 5.0 93.1 1.0

Cobalt binding site 5 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 5 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ B:Co304 b:0.3 occ:1.00 CO B:NCO304 0.0 0.3 1.0 N3 B:NCO304 2.0 0.9 1.0 N5 B:NCO304 2.0 0.1 1.0 N2 B:NCO304 2.0 0.9 1.0 N1 B:NCO304 2.0 0.0 1.0 N4 B:NCO304 2.0 0.3 1.0 N6 B:NCO304 2.0 0.4 1.0 OE1 B:GLU55 4.6 93.3 1.0 OD2 B:ASP70 4.6 91.3 1.0 OE2 B:GLU55 4.8 95.1 1.0

Cobalt binding site 6 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 6 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ B:Co305 b:0.8 occ:1.00 CO B:NCO305 0.0 0.8 1.0 N2 B:NCO305 2.0 0.8 1.0 N4 B:NCO305 2.0 0.6 1.0 N1 B:NCO305 2.0 0.5 1.0 N5 B:NCO305 2.0 0.9 1.0 N6 B:NCO305 2.0 0.7 1.0 N3 B:NCO305 2.0 0.4 1.0 OE1 B:GLU149 3.8 73.1 1.0 ND2 B:ASN150 4.3 60.9 1.0 CB B:GLU149 4.5 50.7 1.0 CB A:GLU57 4.5 81.2 1.0 CD B:GLU149 4.9 61.6 1.0 CG A:GLU57 4.9 91.7 1.0 OD2 B:ASP146 4.9 82.2 1.0

Cobalt binding site 7 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 7 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ C:Co303 b:1.0 occ:1.00 CO C:NCO303 0.0 1.0 1.0 N6 C:NCO303 2.0 0.5 1.0 N4 C:NCO303 2.0 0.9 1.0 N1 C:NCO303 2.0 0.8 1.0 N3 C:NCO303 2.0 0.4 1.0 N5 C:NCO303 2.0 0.2 1.0 N2 C:NCO303 2.0 1.0 1.0 OE1 C:GLU55 3.9 93.5 1.0 OE2 C:GLU55 4.3 79.8 1.0 CD C:GLU55 4.6 85.0 1.0 O C:LEU50 4.7 75.4 1.0

Cobalt binding site 8 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 8 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ C:Co304 b:0.7 occ:1.00 CO C:NCO304 0.0 0.7 1.0 N1 C:NCO304 2.0 0.1 1.0 N4 C:NCO304 2.0 0.2 1.0 N3 C:NCO304 2.0 0.9 1.0 N6 C:NCO304 2.0 0.0 1.0 N5 C:NCO304 2.0 0.9 1.0 N2 C:NCO304 2.0 0.8 1.0 OD1 C:ASP85 3.8 99.4 1.0 OE1 C:GLU81 4.1 0.1 1.0 O C:HOH416 4.6 78.2 1.0 CD C:GLU81 4.9 0.8 1.0 CG C:ASP85 4.9 92.5 1.0

Cobalt binding site 9 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 9 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ D:Co302 b:0.0 occ:1.00 CO D:NCO302 0.0 0.0 1.0 N2 D:NCO302 2.0 0.1 1.0 N1 D:NCO302 2.0 0.4 1.0 N6 D:NCO302 2.0 0.7 1.0 N4 D:NCO302 2.0 0.9 1.0 N3 D:NCO302 2.0 0.1 1.0 N5 D:NCO302 2.0 0.2 1.0 OE1 D:GLU81 4.0 0.7 1.0 CD D:GLU81 4.4 99.5 1.0 OE2 D:GLU81 4.5 99.0 1.0 OE1 D:GLU147 4.9 92.0 1.0

Cobalt binding site 10 out of 14 in the Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 10 of Crystal Structure of the Cytosolic Domain of the Cora MG2+ Channel From Escherichia Coli in Complex with Magnesium and Cobalt Hexammine within 5.0Å range: probe atom residue distance (Å) B Occ D:Co303 b:0.5 occ:1.00 CO D:NCO303 0.0 0.5 1.0 N2 D:NCO303 2.0 0.9 1.0 N4 D:NCO303 2.0 0.4 1.0 N5 D:NCO303 2.0 0.5 1.0 N1 D:NCO303 2.0 0.9 1.0 N3 D:NCO303 2.0 0.3 1.0 N6 D:NCO303 2.0 0.1 1.0 OE1 D:GLU149 4.0 67.9 1.0 OD2 D:ASP146 4.2 0.7 1.0 CB E:GLU57 4.7 88.1 1.0 OD1 D:ASP146 4.8 0.2 1.0 CG D:ASP146 4.8 94.7 1.0 OD1 D:ASN150 4.9 67.8 1.0 O E:HOH404 4.9 47.8 1.0 CG E:GLU57 4.9 0.7 1.0

M.Lerche, H.Sandhu, L.Flockner, M.Hogbom, M.Rapp. Structure and Cooperativity of the Cytosolic Domain of the Cora Mg(2+) Channel From Escherichia Coli. Structure V. 25 1175 2017.
ISSN: ISSN 1878-4186
PubMed: 28669631
DOI: 10.1016/J.STR.2017.05.024