Cobalt in PDB 5ydh: Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A

All present enzymatic activity of Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A:
3.1.1.7;

The structure of Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A, PDB code: 5ydh was solved by Q.Han, H.Guan, H.Robinson, H.Ding, C.Liao, J.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.93 / 3.21
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	148.659, 148.659, 226.021, 90.00, 90.00, 120.00
R / Rfree (%)	20.7 / 23.1

The binding sites of Cobalt atom in the Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A (pdb code 5ydh). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A, PDB code: 5ydh:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A within 5.0Å range: probe atom residue distance (Å) B Occ A:Co820 b:30.0 occ:1.00 NE2 A:HIS416 2.2 20.0 1.0 CE1 A:HIS416 2.9 20.0 1.0 CD2 A:HIS416 3.4 20.0 1.0 ND1 A:HIS416 4.1 20.0 1.0 OE2 A:GLU410 4.1 0.1 1.0 CG A:HIS416 4.4 20.0 1.0 CD A:GLU410 4.4 0.6 1.0 CG A:GLU410 4.8 0.6 1.0 OE1 A:GLU410 4.8 0.7 1.0

Cobalt binding site 2 out of 2 in the Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Acetylcholinesterase Catalytic Subunits of the Malaria Vector Anopheles Gambiae, 3.2 A within 5.0Å range: probe atom residue distance (Å) B Occ B:Co825 b:30.0 occ:1.00 NE2 B:HIS416 2.3 20.0 1.0 CE1 B:HIS416 3.2 20.0 1.0 CD2 B:HIS416 3.2 20.0 1.0 ND1 B:HIS416 4.3 20.0 1.0 CG B:HIS416 4.4 20.0 1.0 OE1 B:GLU410 4.7 0.1 1.0 CD B:GLU410 4.8 1.0 1.0 OE2 B:GLU410 4.9 0.5 1.0

Q.Han, H.Guan, H.Ding, C.Liao, H.Robinson, J.Li. Crystal Structures of Acetylcholinesterase of the Malaria Vector Anopheles Gambiae Reveal A Polymerization Interface, Ligand Binding Residues and Post Translational Modifications To Be Published.