Cobalt in PDB 5ypj: Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant).

All present enzymatic activity of Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant).:
3.4.11.18;

The structure of Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant)., PDB code: 5ypj was solved by C.B.Sandeep, A.Addlagatta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.63 / 2.01
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	49.285, 48.536, 56.353, 90.00, 95.00, 90.00
R / Rfree (%)	15.9 / 20.8

The structure of Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant). also contains other interesting chemical elements:

Chlorine	(Cl)	1 atom
Sodium	(Na)	1 atom

The binding sites of Cobalt atom in the Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant). (pdb code 5ypj). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant)., PDB code: 5ypj:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant).


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant). within 5.0Å range: probe atom residue distance (Å) B Occ A:Co301 b:18.5 occ:1.00 OE1 A:GLU269 2.0 17.4 1.0 O A:HOH486 2.0 22.3 1.0 NE2 A:HIS205 2.1 17.0 1.0 OD2 A:ASP142 2.1 16.4 1.0 OE2 A:GLU238 2.2 18.3 1.0 CD A:GLU269 2.9 18.2 1.0 CG A:ASP142 3.0 17.1 1.0 CD2 A:HIS205 3.0 18.2 1.0 CD A:GLU238 3.0 17.6 1.0 CO A:CO302 3.1 20.8 1.0 CE1 A:HIS205 3.1 16.1 1.0 OE1 A:GLU238 3.2 19.6 1.0 OE2 A:GLU269 3.2 17.5 1.0 OD1 A:ASP142 3.4 16.2 1.0 O A:HOH534 3.6 24.2 1.0 OG1 A:THR236 3.6 14.5 1.0 CG2 A:THR236 3.6 18.5 1.0 CB A:THR236 3.9 16.0 1.0 CG A:HIS205 4.2 17.3 1.0 O A:HOH502 4.2 21.4 1.0 CB A:ASP142 4.2 17.2 1.0 ND1 A:HIS205 4.2 17.9 1.0 CG A:GLU269 4.3 18.5 1.0 CG A:GLU238 4.4 18.1 1.0 CB A:GLU238 4.8 17.8 1.0 NE2 A:HIS212 4.8 29.6 1.0 OD2 A:ASP131 4.9 18.1 1.0

Cobalt binding site 2 out of 2 in the Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant).


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant). within 5.0Å range: probe atom residue distance (Å) B Occ A:Co302 b:20.8 occ:1.00 O A:HOH486 2.0 22.3 1.0 OD1 A:ASP142 2.0 16.2 1.0 OE2 A:GLU269 2.1 17.5 1.0 OD1 A:ASP131 2.1 20.1 1.0 O A:HOH502 2.2 21.4 1.0 OD2 A:ASP131 2.3 18.1 1.0 CG A:ASP131 2.6 18.9 1.0 CG A:ASP142 2.9 17.1 1.0 CD A:GLU269 3.0 18.2 1.0 OD2 A:ASP142 3.1 16.4 1.0 CO A:CO301 3.1 18.5 1.0 OE1 A:GLU269 3.3 17.4 1.0 O A:HOH534 4.0 24.2 1.0 OG1 A:THR133 4.0 20.6 1.0 O A:HOH480 4.0 33.5 1.0 CB A:ASP131 4.1 19.1 1.0 OE1 A:GLU238 4.1 19.6 1.0 ND2 A:ASN144 4.2 18.4 1.0 CB A:ASP142 4.3 17.2 1.0 CG A:GLU269 4.4 18.5 1.0 N A:THR143 4.5 17.8 1.0 OE2 A:GLU238 4.6 18.3 1.0 CD A:GLU238 4.7 17.6 1.0 O A:THR143 4.7 18.9 1.0 O A:HOH461 4.7 18.4 1.0 CB A:ASN144 4.7 18.7 1.0 C A:ASP142 4.8 18.7 1.0 CA A:ASP131 4.8 20.4 1.0 O A:VAL132 4.8 21.5 1.0 C A:THR143 4.9 17.1 1.0 CA A:ASP142 4.9 17.7 1.0 CB A:GLU269 4.9 18.3 1.0 N A:VAL132 5.0 20.3 1.0 CG A:ASN144 5.0 19.0 1.0 C A:ASP131 5.0 21.9 1.0

C.B.Sandeep, A.Addlagatta. Mycobacterium Tuberculosis Methionine Aminopeptidase Type 1C (C105N Mutant). To Be Published.