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Cobalt in PDB 6as7: Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp
Enzymatic activity of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp
All present enzymatic activity of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp, PDB code: 6as7
was solved by
T.H.Tahirov,
A.G.Baranovskiy,
N.D.Babayeva,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.20 / 2.95 |
| Space group | P 42 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 151.807, 151.807, 113.299, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 25.9 / 30.1 |
Other elements in 6as7:
The structure of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp
(pdb code 6as7). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp, PDB code: 6as7:
Jump to Cobalt binding site number: 1; 2;
In total 2 binding sites of Cobalt where determined in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp, PDB code: 6as7:
Jump to Cobalt binding site number: 1; 2;
Cobalt binding site 1 out of 2 in 6as7
Go back to
Cobalt Binding Sites List in 6as7
Cobalt binding site 1 out
of 2 in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp within 5.0Å range:
|
Cobalt binding site 2 out of 2 in 6as7
Go back to
Cobalt Binding Sites List in 6as7
Cobalt binding site 2 out
of 2 in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Dna-Primed Dna Template and Dctp within 5.0Å range:
|
Reference:
A.G.Baranovskiy,
V.N.Duong,
N.D.Babayeva,
Y.Zhang,
Y.I.Pavlov,
K.S.Anderson,
T.H.Tahirov.
Activity and Fidelity of Human Dna Polymerase Alpha Depend on Primer Structure. J. Biol. Chem. V. 293 6824 2018.
ISSN: ESSN 1083-351X
PubMed: 29555682
DOI: 10.1074/JBC.RA117.001074
Page generated: Sun Dec 13 10:49:34 2020
ISSN: ESSN 1083-351X
PubMed: 29555682
DOI: 10.1074/JBC.RA117.001074
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