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Atomistry » Cobalt » PDB 6ega-6kfl » 6ega » |
Cobalt in PDB 6ega: IRAK4 in Complex with A Type II InhibitorEnzymatic activity of IRAK4 in Complex with A Type II Inhibitor
All present enzymatic activity of IRAK4 in Complex with A Type II Inhibitor:
2.7.11.1; Protein crystallography data
The structure of IRAK4 in Complex with A Type II Inhibitor, PDB code: 6ega
was solved by
L.Wang,
H.Wu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ega:
The structure of IRAK4 in Complex with A Type II Inhibitor also contains other interesting chemical elements:
Cobalt Binding Sites:
The binding sites of Cobalt atom in the IRAK4 in Complex with A Type II Inhibitor
(pdb code 6ega). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 6 binding sites of Cobalt where determined in the IRAK4 in Complex with A Type II Inhibitor, PDB code: 6ega: Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6; Cobalt binding site 1 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 1 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Cobalt binding site 2 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 2 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Cobalt binding site 3 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 3 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Cobalt binding site 4 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 4 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Cobalt binding site 5 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 5 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Cobalt binding site 6 out of 6 in 6egaGo back to Cobalt Binding Sites List in 6ega
Cobalt binding site 6 out
of 6 in the IRAK4 in Complex with A Type II Inhibitor
Mono view Stereo pair view
Reference:
L.Wang,
R.Ferrao,
Q.Li,
J.M.Hatcher,
H.G.Choi,
S.J.Buhrlage,
N.S.Gray,
H.Wu.
Conformational Flexibility and Inhibitor Binding to Unphosphorylated Interleukin-1 Receptor-Associated Kinase 4 (IRAK4). J.Biol.Chem. V. 294 4511 2019.
Page generated: Tue Jul 30 18:37:24 2024
ISSN: ESSN 1083-351X PubMed: 30679311 DOI: 10.1074/JBC.RA118.005428 |
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