Cobalt in PDB 6lv4: Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2

All present enzymatic activity of Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2:
4.2.1.1;

The structure of Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2, PDB code: 6lv4 was solved by C.U.Kim, J.K.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.358, 41.458, 72.307, 90.00, 104.02, 90.00
R / Rfree (%)	11.3 / 13.9

The binding sites of Cobalt atom in the Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2 (pdb code 6lv4). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2, PDB code: 6lv4:

Cobalt binding site 1 out of 1 in the Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Co- Carbonic Anhydrase II pH 11.0 20 Atm CO2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co303 b:10.1 occ:1.00 HO3 A:BCT304 1.1 18.2 0.0 HE2 A:HIS94 1.2 7.9 1.0 HD1 A:HIS119 1.3 7.0 1.0 HE2 A:HIS96 1.3 7.8 1.0 O A:HOH401 1.6 15.0 0.5 O3 A:BCT304 2.0 18.5 0.5 NE2 A:HIS94 2.0 8.4 1.0 ND1 A:HIS119 2.1 6.7 1.0 O A:HOH411 2.1 12.9 0.5 NE2 A:HIS96 2.1 7.7 1.0 O1 A:BCT304 2.4 12.7 0.5 C A:BCT304 2.7 15.3 0.5 CE1 A:HIS119 3.0 5.9 1.0 CD2 A:HIS94 3.0 7.8 1.0 CE1 A:HIS96 3.0 7.7 1.0 CE1 A:HIS94 3.0 7.7 1.0 HE1 A:HIS119 3.1 5.8 1.0 CD2 A:HIS96 3.1 6.9 1.0 O1 A:CO2305 3.1 12.3 0.5 CG A:HIS119 3.2 6.0 1.0 HE1 A:HIS96 3.2 7.5 1.0 HD2 A:HIS94 3.2 7.5 1.0 HE1 A:HIS94 3.3 7.8 1.0 HB2 A:HIS119 3.3 6.0 1.0 HD2 A:HIS96 3.3 6.9 1.0 HG1 A:THR199 3.5 7.7 0.0 C A:CO2305 3.6 15.3 0.5 CB A:HIS119 3.6 6.0 1.0 OG1 A:THR199 3.7 7.8 1.0 HB3 A:HIS119 3.8 5.9 1.0 O2 A:BCT304 3.8 14.2 0.5 OE1 A:GLU106 4.1 6.5 1.0 NE2 A:HIS119 4.1 5.9 1.0 ND1 A:HIS94 4.1 6.7 1.0 CG A:HIS94 4.2 6.6 1.0 ND1 A:HIS96 4.2 8.1 1.0 HH2 A:TRP209 4.2 6.9 1.0 CD2 A:HIS119 4.3 5.9 1.0 O A:HOH551 4.3 15.9 1.0 CG A:HIS96 4.3 6.1 1.0 O2 A:CO2305 4.3 15.0 0.5 O A:HOH659 4.4 29.0 1.0 H A:THR199 4.7 7.6 1.0 HG23 A:THR200 4.8 10.7 1.0 HE2 A:HIS119 4.9 5.4 1.0 HG23 A:THR199 4.9 7.9 1.0 HD1 A:HIS94 4.9 6.5 1.0 HD1 A:HIS96 5.0 7.3 1.0 O A:HOH672 5.0 22.3 1.0 CD A:GLU106 5.0 6.1 1.0 HG12 A:VAL143 5.0 7.2 1.0

C.U.Kim, J.K.Kim. Metal Substituted Human Carbonic Anhydrase II Under CO2 Pressure To Be Published.