Atomistry » Cobalt » PDB 6kgh-6oxc » 6lzc
Atomistry »
  Cobalt »
    PDB 6kgh-6oxc »
      6lzc »

Cobalt in PDB 6lzc: Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05

Enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05

All present enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05:
3.4.11.18;

Protein crystallography data

The structure of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05, PDB code: 6lzc was solved by C.B.Sandeep, A.Addlagatta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.53 / 1.35
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 47.552, 77.219, 48.651, 90, 91.55, 90
R / Rfree (%) 16.7 / 19.7

Other elements in 6lzc:

The structure of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05 also contains other interesting chemical elements:

Sodium (Na) 1 atom
Magnesium (Mg) 1 atom

Cobalt Binding Sites:

The binding sites of Cobalt atom in the Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05 (pdb code 6lzc). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05, PDB code: 6lzc:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in 6lzc

Go back to Cobalt Binding Sites List in 6lzc
Cobalt binding site 1 out of 2 in the Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co401

b:17.2
occ:1.00
O1 A:EYL403 2.0 17.0 0.8
NE2 A:HIS303 2.0 14.7 1.0
OE2 A:GLU367 2.0 16.1 1.0
OD2 A:ASP240 2.1 14.1 1.0
OE1 A:GLU336 2.2 20.8 1.0
O A:HOH505 2.7 25.1 1.0
N A:EYL403 2.9 28.5 0.8
CE1 A:HIS303 3.0 15.6 1.0
CD A:GLU367 3.0 15.1 1.0
CD2 A:HIS303 3.1 16.1 1.0
CG A:ASP240 3.1 14.6 1.0
CD A:GLU336 3.1 18.0 1.0
CO A:CO402 3.2 14.1 1.0
OE2 A:GLU336 3.3 31.4 1.0
OE1 A:GLU367 3.5 14.4 1.0
OD1 A:ASP240 3.5 13.7 1.0
OG1 A:THR334 3.8 16.3 1.0
C A:EYL403 4.0 36.1 0.8
CG2 A:THR334 4.1 15.7 1.0
O A:EYL403 4.2 35.9 0.8
CG A:HIS303 4.2 15.4 1.0
ND1 A:HIS303 4.2 16.5 1.0
O A:HOH501 4.2 21.6 0.5
CB A:ASP240 4.3 13.4 1.0
CB A:THR334 4.3 15.1 1.0
CG A:GLU367 4.3 15.2 1.0
CG A:GLU336 4.4 17.1 1.0
NE2 A:HIS310 4.6 24.2 1.0
C14 A:EYL403 4.7 43.7 0.8
CB A:GLU336 4.8 16.2 1.0
OD2 A:ASP229 5.0 22.8 1.0

Cobalt binding site 2 out of 2 in 6lzc

Go back to Cobalt Binding Sites List in 6lzc
Cobalt binding site 2 out of 2 in the Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with Kv-P2-4H-05 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Co402

b:14.1
occ:1.00
O1 A:EYL403 1.9 17.0 0.8
OD1 A:ASP240 1.9 13.7 1.0
OD1 A:ASP229 2.0 18.0 1.0
OE1 A:GLU367 2.2 14.4 1.0
O A:HOH501 2.2 21.6 0.5
O A:EYL403 2.3 35.9 0.8
OD2 A:ASP229 2.5 22.8 1.0
CG A:ASP229 2.5 13.7 1.0
N A:EYL403 2.7 28.5 0.8
CG A:ASP240 2.8 14.6 1.0
C A:EYL403 3.0 36.1 0.8
CD A:GLU367 3.0 15.1 1.0
OD2 A:ASP240 3.1 14.1 1.0
CO A:CO401 3.2 17.2 1.0
OE2 A:GLU367 3.3 16.1 1.0
O A:HOH505 3.9 25.1 1.0
OG1 A:THR231 4.0 16.4 1.0
CB A:ASP229 4.1 12.8 1.0
ND2 A:ASN242 4.1 12.8 1.0
CB A:ASP240 4.3 13.4 1.0
O A:LEU241 4.3 11.5 1.0
CG A:GLU367 4.4 15.2 1.0
N A:LEU241 4.4 12.3 1.0
O A:ILE230 4.4 13.7 1.0
O A:HOH617 4.4 26.0 1.0
OE2 A:GLU336 4.5 31.4 1.0
C A:LEU241 4.5 11.5 1.0
C1 A:EYL403 4.6 31.5 0.8
O A:HOH522 4.6 22.5 1.0
C A:ASP240 4.7 12.0 1.0
OE1 A:GLU336 4.7 20.8 1.0
CA A:ASP229 4.8 12.1 1.0
CA A:ASP240 4.8 11.9 1.0
CB A:ASN242 4.8 11.6 1.0
N A:ILE230 4.8 13.1 1.0
CB A:GLU367 4.9 13.3 1.0
CA A:LEU241 4.9 12.5 1.0
CD A:GLU336 4.9 18.0 1.0
C A:ASP229 5.0 11.3 1.0
CG A:ASN242 5.0 12.2 1.0
C A:ILE230 5.0 11.8 1.0

Reference:

C.B.Sandeep, A.Addlagatta. Crystal Structure of Human Methionine Aminopeptidase (HSMETAP1B) in Complex with An-P2-5H-06 To Be Published.
Page generated: Wed Mar 3 13:03:45 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy