Cobalt in PDB 6p4z: Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer

The structure of Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer, PDB code: 6p4z was solved by T.H.Tran, S.K.Taylor, M.N.Stojanovic, L.Tong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.50 / 1.80
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	81.400, 81.400, 33.700, 90.00, 90.00, 120.00
R / Rfree (%)	18.1 / 23.9

The structure of Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer also contains other interesting chemical elements:

Gadolinium	(Gd)	2 atoms
Chlorine	(Cl)	1 atom

The binding sites of Cobalt atom in the Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer (pdb code 6p4z). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer, PDB code: 6p4z:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ B:Co101 b:19.6 occ:0.33 NE2 B:HIS10 2.0 17.3 1.0 O B:HOH216 2.2 22.9 1.0 CE1 B:HIS10 2.9 18.1 1.0 CD2 B:HIS10 3.2 16.3 1.0 ND1 B:HIS10 4.1 20.8 1.0 CG B:HIS10 4.2 15.5 1.0 O B:HOH214 4.6 38.8 1.0

Cobalt binding site 2 out of 2 in the Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Structure of Gadolinium-Caged Cobalt (III) Insulin Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ D:Co102 b:27.3 occ:0.33 NE2 D:HIS10 2.0 23.8 1.0 O D:HOH211 2.5 45.8 1.0 CE1 D:HIS10 2.9 23.5 1.0 CD2 D:HIS10 3.1 23.3 1.0 ND1 D:HIS10 4.1 25.5 1.0 CG D:HIS10 4.2 23.9 1.0

S.K.Taylor, T.H.Tran, M.Z.Liu, P.E.Harris, Y.Sun, S.R.Jambawalikar, L.Tong, M.N.Stojanovic. Insulin Hexamer-Caged Gadolinium Ion As Mri Contrast-O-Phore Chembiochem V. 24 10646 2018.
ISSN: ISSN 1439-4227