Cobalt in PDB 6utp: Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt

The structure of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt, PDB code: 6utp was solved by M.Fellner, K.Huizenga, R.P.Hausinger, J.Hu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	87.93 / 3.55
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	106.210, 106.210, 313.550, 90.00, 90.00, 90.00
R / Rfree (%)	23.1 / 29.8

The binding sites of Cobalt atom in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt (pdb code 6utp). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 6 binding sites of Cobalt where determined in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt, PDB code: 6utp:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6;

Cobalt binding site 1 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ A:Co302 b:71.8 occ:1.00 NE2 A:HIS190 2.0 65.1 1.0 O A:HOH403 2.3 66.9 1.0 O A:HOH401 2.7 64.3 1.0 O A:HOH404 2.8 58.6 1.0 CE1 A:HIS190 3.0 65.1 1.0 CD2 A:HIS190 3.0 65.1 1.0 O2 A:SO4305 3.8 65.8 0.8 ND1 A:HIS190 4.1 65.1 1.0 CG A:HIS190 4.1 65.1 1.0 O1 A:SO4305 4.4 65.8 0.8 S A:SO4305 4.7 65.8 0.8 OD2 A:ASP82 4.8 66.0 1.0

Cobalt binding site 2 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ A:Co303 b:57.3 occ:0.85 OD1 C:ASP231 2.1 55.5 1.0 OD2 C:ASP231 2.1 55.5 1.0 OD2 B:ASP231 2.1 53.3 1.0 OD2 A:ASP231 2.1 53.6 1.0 OD1 A:ASP231 2.1 53.6 1.0 OD1 B:ASP231 2.2 53.3 1.0 CG C:ASP231 2.4 55.5 1.0 CG A:ASP231 2.4 53.6 1.0 CG B:ASP231 2.5 53.3 1.0 O A:HOH402 2.7 49.8 0.8 CB C:ASP231 3.9 55.5 1.0 CB A:ASP231 4.0 53.6 1.0 CB B:ASP231 4.0 53.3 1.0 N C:ASP231 4.6 55.5 1.0 CA C:ASP231 4.6 55.5 1.0 O C:ALA227 4.7 56.0 1.0 CA A:ASP231 4.8 53.6 1.0 NE B:ARG228 4.9 51.2 1.0 N A:ASP231 4.9 53.6 1.0 CA B:ASP231 4.9 53.3 1.0 O A:ALA227 5.0 53.9 1.0

Cobalt binding site 3 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ C:Co302 b:79.4 occ:1.00 NE2 C:HIS190 2.3 70.9 1.0 O C:HOH401 2.5 75.2 1.0 O C:HOH402 2.5 70.5 1.0 O C:HOH403 3.0 74.8 1.0 CE1 C:HIS190 3.2 70.9 1.0 CD2 C:HIS190 3.3 70.9 1.0 OD2 C:ASP82 4.0 78.4 1.0 ND1 C:HIS190 4.4 70.9 1.0 CG C:HIS190 4.4 70.9 1.0 O4 C:SO4303 4.5 71.8 0.8 O1 C:SO4303 4.7 71.8 0.8 OD1 C:ASP82 4.8 78.4 1.0 CG C:ASP82 4.9 78.4 1.0

Cobalt binding site 4 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ D:Co302 b:58.7 occ:0.82 OD2 F:ASP231 2.1 56.3 1.0 OD2 E:ASP231 2.1 56.9 1.0 OD2 D:ASP231 2.1 54.9 1.0 OD1 D:ASP231 2.1 54.9 1.0 OD1 F:ASP231 2.1 56.3 1.0 OD1 E:ASP231 2.1 56.9 1.0 O F:HOH401 2.2 53.4 0.8 CG D:ASP231 2.3 54.9 1.0 CG F:ASP231 2.4 56.3 1.0 CG E:ASP231 2.4 56.9 1.0 CB D:ASP231 3.8 54.9 1.0 CB F:ASP231 3.9 56.3 1.0 CB E:ASP231 3.9 56.9 1.0 N D:ASP231 4.5 54.9 1.0 CA D:ASP231 4.5 54.9 1.0 CA E:ASP231 4.7 56.9 1.0 CA F:ASP231 4.7 56.3 1.0 N E:ASP231 4.8 56.9 1.0 N F:ASP231 4.8 56.3 1.0 O D:ALA227 4.8 54.3 1.0 NE D:ARG228 4.9 53.7 1.0 NE E:ARG228 5.0 59.5 1.0

Cobalt binding site 5 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 5 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ D:Co303 b:76.7 occ:0.95 CE1 D:HIS190 2.4 65.6 1.0 NE2 D:HIS190 2.5 65.6 1.0 O D:HOH401 2.6 66.7 0.9 O D:HOH403 2.8 66.4 0.9 O D:HOH402 2.8 68.3 0.9 ND1 D:HIS190 3.7 65.6 1.0 CD2 D:HIS190 3.9 65.6 1.0 O3 D:SO4305 4.1 66.9 0.8 OD1 D:ASP82 4.3 66.5 1.0 CB D:LEU84 4.4 66.4 1.0 CG D:HIS190 4.4 65.6 1.0 OE2 D:GLU55 4.5 68.3 1.0 O2 D:SO4305 4.6 66.9 0.8 OD2 D:ASP82 4.6 66.5 1.0 CG D:ASP82 4.9 66.5 1.0 S D:SO4305 5.0 66.9 0.8

Cobalt binding site 6 out of 6 in the Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 6 of Lare, A Sulfur Transferase Involved in Synthesis of the Cofactor For Lactate Racemase in Complex with Cobalt within 5.0Å range: probe atom residue distance (Å) B Occ F:Co302 b:86.4 occ:0.80 OD2 F:ASP82 2.2 74.8 1.0 O F:HOH402 2.5 73.0 0.8 NE2 F:HIS190 2.6 74.4 1.0 O F:HOH403 2.8 64.0 0.8 CE1 F:HIS190 2.9 74.4 1.0 CG F:ASP82 3.2 74.8 1.0 OD1 F:ASP82 3.5 74.8 1.0 CD2 F:HIS190 4.0 74.4 1.0 ND1 F:HIS190 4.2 74.4 1.0 CB F:ASP82 4.6 74.8 1.0 CG F:HIS190 4.7 74.4 1.0 CB F:LEU84 4.8 72.0 1.0

M.Fellner, M.Fellner, K.Huizenga, R.P.Hausinger, J.Hu. N/A N/A.