Cobalt in PDB 7eq2: Crystal Structure of Gdp-Bound RAB1A-T75D

All present enzymatic activity of Crystal Structure of Gdp-Bound RAB1A-T75D:
3.6.5.2;

The structure of Crystal Structure of Gdp-Bound RAB1A-T75D, PDB code: 7eq2 was solved by Y.L.Cao, D.D.Gu, S.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.12 / 1.55
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	39.489, 50.598, 52.626, 76.95, 84.62, 86.27
R / Rfree (%)	16 / 18.5

The structure of Crystal Structure of Gdp-Bound RAB1A-T75D also contains other interesting chemical elements:

Arsenic	(As)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Cobalt atom in the Crystal Structure of Gdp-Bound RAB1A-T75D (pdb code 7eq2). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 4 binding sites of Cobalt where determined in the Crystal Structure of Gdp-Bound RAB1A-T75D, PDB code: 7eq2:
Jump to Cobalt binding site number: 1; 2; 3; 4;

Cobalt binding site 1 out of 4 in the Crystal Structure of Gdp-Bound RAB1A-T75D


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Gdp-Bound RAB1A-T75D within 5.0Å range: probe atom residue distance (Å) B Occ A:Co203 b:11.7 occ:1.00 CO A:NCO203 0.0 11.7 1.0 N6 A:NCO203 2.0 17.6 1.0 N4 A:NCO203 2.0 17.2 1.0 N3 A:NCO203 2.0 19.0 1.0 N5 A:NCO203 2.0 14.3 1.0 N1 A:NCO203 2.0 12.8 1.0 N2 A:NCO203 2.0 12.9 1.0 O A:ASP110 3.7 13.1 1.0 OE2 A:GLU115 4.0 18.9 1.0 O A:ALA113 4.0 15.2 1.0 O A:HOH369 4.5 33.7 1.0 O A:ARG111 4.5 13.4 1.0 O A:HOH329 4.6 39.8 1.0 O A:HOH400 4.7 17.1 1.0 C A:ARG111 4.9 12.4 1.0 C A:ASP110 4.9 11.5 1.0

Cobalt binding site 2 out of 4 in the Crystal Structure of Gdp-Bound RAB1A-T75D


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Crystal Structure of Gdp-Bound RAB1A-T75D within 5.0Å range: probe atom residue distance (Å) B Occ A:Co204 b:14.4 occ:0.50 CO A:NCO204 0.0 14.4 0.5 N3 A:NCO204 2.0 24.1 0.5 N6 A:NCO204 2.0 26.5 0.5 N2 A:NCO204 2.0 14.7 0.5 N4 A:NCO204 2.0 19.2 0.5 N5 A:NCO204 2.0 14.5 0.5 N1 A:NCO204 2.0 16.3 0.5 O A:ALA32 3.8 15.2 1.0 O A:HOH346 4.0 42.6 1.0 O A:ILE50 4.2 15.4 1.0 OD1 A:ASP33 4.4 19.9 1.0 O A:HOH436 4.7 11.7 1.0 C A:ALA32 4.9 11.3 1.0

Cobalt binding site 3 out of 4 in the Crystal Structure of Gdp-Bound RAB1A-T75D


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Crystal Structure of Gdp-Bound RAB1A-T75D within 5.0Å range: probe atom residue distance (Å) B Occ B:Co203 b:11.7 occ:1.00 CO B:NCO203 0.0 11.7 1.0 N4 B:NCO203 2.0 20.3 1.0 N3 B:NCO203 2.0 13.9 1.0 N6 B:NCO203 2.0 14.8 1.0 N5 B:NCO203 2.0 14.5 1.0 N2 B:NCO203 2.0 14.1 1.0 N1 B:NCO203 2.0 14.9 1.0 O B:ASP110 3.7 11.1 1.0 O B:ALA113 3.9 13.9 1.0 OE2 B:GLU115 4.0 20.0 1.0 O B:HOH451 4.0 35.7 1.0 O B:ARG111 4.5 12.2 1.0 O B:HOH447 4.6 29.6 1.0 O B:HOH382 4.7 15.7 1.0 O B:HOH453 4.8 44.2 1.0 C B:ARG111 4.9 12.4 1.0 C B:ASP110 4.9 10.3 1.0

Cobalt binding site 4 out of 4 in the Crystal Structure of Gdp-Bound RAB1A-T75D


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Crystal Structure of Gdp-Bound RAB1A-T75D within 5.0Å range: probe atom residue distance (Å) B Occ B:Co204 b:35.9 occ:1.00 CO B:NCO204 0.0 35.9 1.0 N2 B:NCO204 2.0 42.9 1.0 N5 B:NCO204 2.0 40.5 1.0 N6 B:NCO204 2.0 41.0 1.0 N1 B:NCO204 2.0 34.0 1.0 N3 B:NCO204 2.0 41.6 1.0 N4 B:NCO204 2.0 38.2 1.0 O B:ALA32 3.9 19.8 1.0 O B:ILE50 3.9 14.1 1.0 OD1 B:ASP33 4.3 35.5 1.0 O B:HOH450 4.5 35.4 1.0 O B:HOH445 4.5 16.4 1.0 O B:HOH441 4.8 34.6 1.0

Y.L.Cao, D.D.Gu, S.Gao. Crystal Structure of Gdp-Bound RAB1A-T75D To Be Published.