Cobalt in PDB 7ruu: Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
Enzymatic activity of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
All present enzymatic activity of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin:
2.5.1.17;
2.5.1.17;
Protein crystallography data
The structure of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin, PDB code: 7ruu
was solved by
R.Mascarenhas,
H.Gouda,
M.Koutmos,
R.Banerjee,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 36.16 / 1.85 |
| Space group | H 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 121.807, 121.807, 171.629, 90, 90, 120 |
| R / Rfree (%) | 17.7 / 20.2 |
Other elements in 7ruu:
The structure of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin also contains other interesting chemical elements:
| Potassium | (K) | 3 atoms |
Cobalt Binding Sites:
The binding sites of Cobalt atom in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
(pdb code 7ruu). This binding sites where shown within
5.0 Angstroms radius around Cobalt atom.
In total 4 binding sites of Cobalt where determined in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin, PDB code: 7ruu:
Jump to Cobalt binding site number: 1; 2; 3; 4;
In total 4 binding sites of Cobalt where determined in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin, PDB code: 7ruu:
Jump to Cobalt binding site number: 1; 2; 3; 4;
Cobalt binding site 1 out of 4 in 7ruu
Go back to
Cobalt Binding Sites List in 7ruu
Cobalt binding site 1 out
of 4 in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 1 of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin within 5.0Å range:
|
Cobalt binding site 2 out of 4 in 7ruu
Go back to
Cobalt Binding Sites List in 7ruu
Cobalt binding site 2 out
of 4 in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 2 of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin within 5.0Å range:
|
Cobalt binding site 3 out of 4 in 7ruu
Go back to
Cobalt Binding Sites List in 7ruu
Cobalt binding site 3 out
of 4 in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 3 of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin within 5.0Å range:
|
Cobalt binding site 4 out of 4 in 7ruu
Go back to
Cobalt Binding Sites List in 7ruu
Cobalt binding site 4 out
of 4 in the Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Cobalt with other atoms in the Co binding
site number 4 of Structure of Human Atp:Cobalamin Adenosyltransferase R190C Bound to Adenosylcobalamin within 5.0Å range:
|
Reference:
H.Gouda,
R.Mascarenhas,
S.Pillay,
M.Ruetz,
M.Koutmos,
R.Banerjee.
Patient Mutations in Human Atp:Cob(I)Alamin Adenosyltransferase Differentially Affect Its Catalytic Versus Chaperone Functions. J.Biol.Chem. 01373 2021.
ISSN: ESSN 1083-351X
PubMed: 34757128
DOI: 10.1016/J.JBC.2021.101373
Page generated: Thu Nov 25 08:58:59 2021
ISSN: ESSN 1083-351X
PubMed: 34757128
DOI: 10.1016/J.JBC.2021.101373
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