Cobalt in PDB 8dyl: Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin

All present enzymatic activity of Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin:
5.4.99.2;

The structure of Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin, PDB code: 8dyl was solved by R.N.Mascarenhas, H.Gouda, R.Banerjee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.76 / 1.90
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	59.377, 136.07, 196.015, 90, 90, 90
R / Rfree (%)	17.5 / 20.9

The binding sites of Cobalt atom in the Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin (pdb code 8dyl). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin, PDB code: 8dyl:

Cobalt binding site 1 out of 1 in the Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Crystal Structure of Human Methylmalonyl-Coa Mutase Bound to Aquocobalamin within 5.0Å range: probe atom residue distance (Å) B Occ B:Co801 b:29.2 occ:1.00 CO B:B12801 0.0 29.2 1.0 N21 B:B12801 1.8 31.0 1.0 N23 B:B12801 1.9 28.8 1.0 N24 B:B12801 1.9 29.7 1.0 N22 B:B12801 1.9 33.4 1.0 NE2 B:HIS627 2.3 36.3 1.0 O B:HOH1045 2.5 54.1 1.0 C4 B:B12801 2.9 33.8 1.0 C1 B:B12801 2.9 32.2 1.0 C19 B:B12801 2.9 31.6 1.0 C9 B:B12801 2.9 30.5 1.0 C11 B:B12801 2.9 28.8 1.0 C14 B:B12801 2.9 26.4 1.0 C16 B:B12801 2.9 22.8 1.0 C6 B:B12801 3.0 35.5 1.0 CD2 B:HIS627 3.2 30.9 1.0 C10 B:B12801 3.3 34.8 1.0 CE1 B:HIS627 3.3 32.3 1.0 C5 B:B12801 3.3 33.1 1.0 C15 B:B12801 3.4 27.4 1.0 C20 B:B12801 3.6 28.3 1.0 C18 B:B12801 4.1 29.8 1.0 C2 B:B12801 4.1 32.5 1.0 C3 B:B12801 4.1 34.3 1.0 C13 B:B12801 4.2 22.6 1.0 C12 B:B12801 4.2 29.2 1.0 C17 B:B12801 4.2 25.5 1.0 C8 B:B12801 4.2 39.0 1.0 C7 B:B12801 4.3 40.5 1.0 ND1 B:HIS627 4.4 32.7 1.0 CG B:HIS627 4.4 28.9 1.0 C26 B:B12801 4.5 36.5 1.0 C48 B:B12801 4.7 22.5 1.0 C46 B:B12801 4.8 26.8 1.0 O B:HOH1021 4.8 31.9 1.0 C54 B:B12801 4.8 23.5 1.0 C35 B:B12801 4.8 40.1 1.0 C42 B:B12801 4.9 35.1 1.0 C53 B:B12801 4.9 18.1 1.0

H.Gouda, R.Mascarenhas, M.Ruetz, M.Yaw, R.Banerjee. Allosteric Control of Metal Redox State Regulates Coenzyme B12 Repair To Be Published.