Cobalt in PDB 8ebo: Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions

The structure of Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions, PDB code: 8ebo was solved by E.V.Chen, L.A.Yatsunyk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.71 / 1.98
Space group	F 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	42.053, 47.474, 119.597, 90, 90, 90
R / Rfree (%)	23.1 / 27.9

The structure of Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Cobalt atom in the Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions (pdb code 8ebo). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions, PDB code: 8ebo:

Cobalt binding site 1 out of 1 in the Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Homopurine Parallel G-Quadruplex From Human Chromosome 7 Stabilized By K+ Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Co105 b:120.5 occ:0.50 OP1 A:DA17 3.7 94.2 1.0 P A:DA17 4.8 95.5 1.0 OP1 A:DG13 5.0 85.1 1.0

M.Ye, E.V.Chen, S.H.Pfeil, K.N.Martin, T.Atrafi, S.Yun, Z.Martinez, L.A.Yatsunyk. Homopurine Guanine-Rich Sequences in Complex with N-Methyl Mesoporphyrin IX Form Parallel G-Quadruplex Dimers and Display A Unique Symmetry Tetrad. Bioorg.Med.Chem. V. 77 17112 2022.
ISSN: ESSN 1464-3391
PubMed: 36508994
DOI: 10.1016/J.BMC.2022.117112