Cobalt in PDB 8ew4: Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1

The structure of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1, PDB code: 8ew4 was solved by M.Gucwa, D.R.Cooper, J.Unciano, K.Lea, L.Kim, J.Lenkiewicz, I.Starban, A.J.Stewart, W.Minor, Center For Structural Genomics Of Infectiousdiseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.56 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	172.775, 38.503, 95.865, 90, 103.55, 90
R / Rfree (%)	17.7 / 25.5

The binding sites of Cobalt atom in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1 (pdb code 8ew4). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 4 binding sites of Cobalt where determined in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1, PDB code: 8ew4:
Jump to Cobalt binding site number: 1; 2; 3; 4;

Cobalt binding site 1 out of 4 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co604 b:45.7 occ:1.00 NE2 A:HIS9 2.2 56.5 1.0 OD1 A:ASP1 2.4 51.9 1.0 O A:HOH2196 2.4 35.2 1.0 O A:ASP1 2.5 60.7 1.0 N A:ASP1 2.6 58.6 1.0 CE1 A:HIS9 2.8 52.5 1.0 C A:ASP1 3.3 60.5 1.0 CD2 A:HIS9 3.3 54.2 1.0 CA A:ASP1 3.4 60.7 1.0 CG A:ASP1 3.5 55.7 1.0 CB A:ASP1 4.0 60.0 1.0 ND1 A:HIS9 4.0 50.5 1.0 O A:HOH2206 4.1 36.7 1.0 O A:HOH2133 4.2 27.1 1.0 CG A:HIS9 4.3 49.5 1.0 NZ A:LYS12 4.3 52.8 1.0 CD2 A:HIS3 4.4 69.1 1.0 CE A:LYS12 4.5 51.3 1.0 OD2 A:ASP1 4.5 54.8 1.0 N A:ALA2 4.6 63.9 1.0 O A:HOH2168 4.7 41.4 1.0

Cobalt binding site 2 out of 4 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co609 b:86.3 occ:1.00 NE2 A:HIS128 2.7 37.2 1.0 CE1 A:HIS128 3.6 35.6 1.0 CD2 A:HIS128 3.7 36.3 1.0 ND1 A:HIS128 4.8 34.7 1.0 CG A:HIS128 4.9 34.4 1.0

Cobalt binding site 3 out of 4 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co610 b:78.9 occ:1.00 OD2 A:ASP471 3.0 59.2 1.0 OD1 A:ASP471 3.0 54.9 1.0 CG A:ASP471 3.4 54.4 1.0 CD A:ARG472 3.8 41.8 1.0 CG A:ARG472 4.3 39.9 1.0 CB A:ASP471 4.9 52.5 1.0

Cobalt binding site 4 out of 4 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co612 b:115.5 occ:1.00 O A:HOH2104 2.3 50.8 1.0 O A:HOH2205 2.4 50.3 1.0 O A:HOH2139 3.0 45.6 1.0 OG A:SER270 3.4 43.2 1.0 OD1 A:ASN267 3.6 40.1 1.0 CB A:SER270 4.2 43.4 1.0 CG A:ASN267 4.7 38.5 1.0 OE2 A:GLU230 4.7 44.2 1.0 OD2 A:ASP269 4.8 56.0 1.0

D.Wu, I.G.Shabalin, M.P.Czub, S.Arya, U.Schwarz-Linek, C.A.Blindauer, D.R.Cooper, M.Gucwa, W.Minor, A.J.Stewart. Human Serum Albumin with Cobalt (II) and Myristic Acid To Be Published.