Cobalt in PDB 8ew7: Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2

The structure of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2, PDB code: 8ew7 was solved by M.Gucwa, D.R.Cooper, A.J.Stewart, W.Minor, Center For Structural Genomicsof Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.28 / 3.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	166.104, 38.301, 96.719, 90, 105.04, 90
R / Rfree (%)	16.7 / 27.4

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 11;

Binding sites:

The binding sites of Cobalt atom in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 (pdb code 8ew7). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 11 binding sites of Cobalt where determined in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2, PDB code: 8ew7:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Cobalt binding site 1 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co602 b:117.3 occ:1.00 OD2 A:ASP249 1.9 77.2 1.0 NE2 A:HIS67 2.2 55.9 1.0 CG A:ASP249 3.0 76.9 1.0 CD2 A:HIS67 3.1 54.4 1.0 CE1 A:HIS67 3.1 54.2 1.0 OD1 A:ASP249 3.7 66.1 1.0 OE2 A:GLU252 4.0 74.6 1.0 CB A:ASP249 4.1 80.4 1.0 ND1 A:HIS67 4.2 51.9 1.0 CG A:HIS67 4.2 52.9 1.0 CB A:GLU252 4.6 66.6 1.0 CB A:LEU251 5.0 46.2 1.0

Cobalt binding site 2 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co604 b:116.1 occ:1.00 NE2 A:HIS9 1.9 67.5 1.0 O A:HOH712 2.0 61.9 1.0 OD2 A:ASP13 2.0 58.4 1.0 O A:HOH710 2.1 40.2 1.0 O A:HOH719 2.1 32.9 1.0 O A:HOH709 2.4 11.6 1.0 CE1 A:HIS9 2.8 68.8 1.0 CD2 A:HIS9 2.9 66.7 1.0 CG A:ASP13 3.2 55.3 1.0 OD1 A:ASP13 3.7 53.7 1.0 ND1 A:HIS9 3.9 70.3 1.0 CG A:HIS9 3.9 68.3 1.0 CB A:ASP13 4.4 51.8 1.0 O A:HIS9 4.7 64.7 1.0

Cobalt binding site 3 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co607 b:118.8 occ:1.00 OE1 A:GLU244 2.1 79.3 1.0 ND1 A:HIS247 2.7 92.8 1.0 CB A:ASP249 3.0 80.4 1.0 CE1 A:HIS247 3.3 89.3 1.0 CD A:GLU244 3.4 71.4 1.0 N A:ASP249 4.0 66.0 1.0 CG A:HIS247 4.0 83.5 1.0 OD2 A:ASP249 4.1 77.2 1.0 CA A:ASP249 4.1 74.8 1.0 CG A:ASP249 4.1 76.9 1.0 OE2 A:GLU244 4.2 74.2 1.0 CG A:GLU244 4.3 64.6 1.0 O A:GLU244 4.3 48.7 1.0 OE2 A:GLU252 4.5 74.6 1.0 NE2 A:HIS247 4.5 88.1 1.0 CB A:HIS247 4.6 75.2 1.0 CB A:GLU252 4.7 66.6 1.0 O A:ASP249 4.7 71.9 1.0 CD A:GLU252 4.9 72.7 1.0 CD2 A:HIS247 4.9 87.3 1.0 C A:ASP249 4.9 74.4 1.0

Cobalt binding site 4 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co608 b:99.2 occ:1.00 OE1 A:GLU252 1.9 65.7 1.0 OE2 A:GLU244 2.7 74.2 1.0 O A:HOH717 2.8 8.4 1.0 CD A:GLU252 3.1 72.7 1.0 CD A:GLU244 3.7 71.4 1.0 OD2 A:ASP256 3.8 60.6 1.0 CG A:GLU252 3.8 71.4 1.0 OE2 A:GLU252 4.1 74.6 1.0 OD1 A:ASP256 4.2 60.7 1.0 CG A:GLU244 4.4 64.6 1.0 CG A:ASP256 4.4 61.8 1.0 OE1 A:GLU244 4.5 79.3 1.0 CE A:LYS240 4.7 84.3 1.0 CB A:GLU252 5.0 66.6 1.0

Cobalt binding site 5 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 5 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co609 b:53.8 occ:1.00 NE2 A:HIS128 2.5 43.5 1.0 O A:HOH720 3.1 2.5 1.0 CD2 A:HIS128 3.4 41.5 1.0 CE1 A:HIS128 3.5 43.0 1.0 CG A:HIS128 4.5 40.6 1.0 ND1 A:HIS128 4.5 42.0 1.0

Cobalt binding site 6 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 6 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co610 b:58.9 occ:1.00 OD2 A:ASP471 3.2 39.2 1.0 OD1 A:ASP471 3.3 40.8 1.0 CG A:ASP471 3.6 41.0 1.0 CD A:ARG472 3.8 47.0 1.0 CG A:ARG472 4.5 46.2 1.0 NE A:ARG472 4.8 48.2 1.0

Cobalt binding site 7 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 7 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co611 b:79.1 occ:1.00 NE2 A:HIS440 2.0 48.9 1.0 CE1 A:HIS440 2.9 50.3 1.0 CD2 A:HIS440 3.1 47.6 1.0 ND1 A:HIS440 4.0 49.1 1.0 CG A:HIS440 4.2 47.0 1.0 SG A:CYS448 4.8 36.6 1.0 CD A:LYS444 4.9 69.2 1.0

Cobalt binding site 8 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 8 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co613 b:102.3 occ:1.00 OE1 A:GLU57 2.3 59.5 1.0 ND1 A:HIS3 2.4 125.4 1.0 O A:HOH706 2.5 43.6 1.0 OE2 A:GLU57 2.7 73.6 1.0 CD A:GLU57 2.7 63.7 1.0 N A:HIS3 2.7 111.6 1.0 CE1 A:HIS3 2.8 119.8 1.0 CG A:HIS3 3.3 124.8 1.0 NE2 A:HIS3 3.8 125.4 1.0 CA A:HIS3 3.8 106.7 1.0 CB A:HIS3 4.0 113.7 1.0 CD2 A:HIS3 4.0 128.2 1.0 N A:LYS4 4.0 88.9 1.0 CG A:GLU57 4.1 62.3 1.0 C A:HIS3 4.5 93.9 1.0 NZ A:LYS4 4.8 97.5 1.0 CG A:LYS4 4.9 95.2 1.0

Cobalt binding site 9 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 9 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co614 b:68.0 occ:1.00 NE2 A:HIS146 2.4 26.8 1.0 CE1 A:HIS146 3.1 26.9 1.0 CD2 A:HIS146 3.5 26.9 1.0 CG A:LYS190 3.8 39.3 1.0 CD A:LYS190 4.3 43.3 1.0 ND1 A:HIS146 4.3 26.0 1.0 CG A:HIS146 4.6 27.1 1.0 NZ A:LYS190 5.0 46.0 1.0

Cobalt binding site 10 out of 11 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 10 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co615 b:85.1 occ:1.00 OE2 A:GLU311 2.3 95.6 1.0 NE2 A:HIS367 3.0 84.3 1.0 CD A:GLU311 3.0 99.4 1.0 OE1 A:GLU311 3.1 100.0 1.0 CD2 A:HIS367 3.4 81.4 1.0 CE1 A:HIS367 4.2 84.4 1.0 OE1 A:GLU368 4.3 82.4 1.0 CG A:GLU311 4.5 96.3 1.0 CG A:HIS367 4.7 80.2 1.0

D.Wu, I.G.Shabalin, M.P.Czub, S.Arya, U.Schwarz-Linek, C.A.Blindauer, D.R.Cooper, M.Gucwa, W.Minor, A.J.Stewart. Human Serum Albumin with Cobalt (II) and Myristic Acid To Be Published.