Cobalt in PDB 8ey5: Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3

The structure of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3, PDB code: 8ey5 was solved by M.Gucwa, D.R.Cooper, A.J.Stewart, W.Minor, Center For Structural Genomicsof Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.18 / 3.10
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	185.966, 38.548, 93.409, 90, 103.75, 90
R / Rfree (%)	20.4 / 29.5

The binding sites of Cobalt atom in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 (pdb code 8ey5). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 5 binding sites of Cobalt where determined in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3, PDB code: 8ey5:
Jump to Cobalt binding site number: 1; 2; 3; 4; 5;

Cobalt binding site 1 out of 5 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co604 b:139.4 occ:1.00 O A:HOH705 1.9 60.3 1.0 NE2 A:HIS9 2.0 87.0 1.0 O A:HOH721 2.3 46.8 1.0 CE1 A:HIS9 2.5 89.7 1.0 OD2 A:ASP13 2.7 77.2 1.0 CD2 A:HIS9 3.3 83.0 1.0 ND1 A:HIS9 3.8 87.2 1.0 CG A:ASP13 3.8 75.7 1.0 CG A:HIS9 4.1 83.3 1.0 OD1 A:ASP13 4.2 79.2 1.0 OD1 A:ASP1 4.5 111.7 1.0 NE2 A:HIS3 4.6 108.2 1.0 OD2 A:ASP1 4.6 102.1 1.0 CG A:ASP1 5.0 109.3 1.0

Cobalt binding site 2 out of 5 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co607 b:95.1 occ:1.00 O A:HOH710 2.2 65.8 1.0 OD1 A:ASP256 2.4 54.5 1.0 O A:HOH702 2.4 37.4 1.0 O A:HOH720 2.5 25.6 1.0 CG A:ASP256 3.4 51.8 1.0 OD2 A:ASP256 3.6 51.8 1.0 O A:GLU252 4.6 52.4 1.0 OE1 A:GLU252 4.7 66.0 1.0 CB A:ASP256 4.8 49.2 1.0 CG A:GLU244 4.9 51.9 1.0

Cobalt binding site 3 out of 5 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 3 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co609 b:74.5 occ:1.00 NE2 A:HIS128 2.2 65.0 1.0 CE1 A:HIS128 3.1 64.8 1.0 CD2 A:HIS128 3.1 62.3 1.0 ND1 A:HIS128 4.1 62.1 1.0 CG A:HIS128 4.2 60.3 1.0

Cobalt binding site 4 out of 5 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 4 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co610 b:80.2 occ:1.00 OD2 A:ASP471 3.3 68.1 1.0 OD1 A:ASP471 3.4 68.1 1.0 CG A:ASP471 3.7 67.8 1.0 CD A:ARG472 5.0 62.4 1.0

Cobalt binding site 5 out of 5 in the Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 5 of Human Serum Albumin with Cobalt (II) and Myristic Acid - Crystal 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co611 b:75.9 occ:1.00 NE2 A:HIS440 3.2 61.3 1.0 CE A:LYS444 3.4 63.4 1.0 SG A:CYS448 3.5 53.3 1.0 CE1 A:HIS440 3.6 63.4 1.0 NZ A:LYS444 3.8 62.2 1.0 CE2 A:TYR452 4.4 55.6 1.0 CB A:CYS448 4.4 51.2 1.0 CD2 A:HIS440 4.4 60.2 1.0 OH A:TYR452 4.6 60.2 1.0 CD A:LYS444 4.7 61.9 1.0 ND1 A:HIS440 4.8 63.9 1.0 CE A:LYS436 4.8 62.2 1.0 CG A:LYS444 4.9 63.4 1.0 CA A:CYS448 5.0 49.1 1.0

D.Wu, I.G.Shabalin, M.P.Czub, S.Arya, U.Schwarrz-Linek, C.A.Blindauer, D.R.Cooper, M.Gucwa, W.Minor, A.J.Stewart. Human Serum Albumin with Cobalt (II) and Myristic Acid To Be Published.