Cobalt in PDB 9dba: Co-Bound Structure of Computationally Designed Homotrimer TET4

The structure of Co-Bound Structure of Computationally Designed Homotrimer TET4, PDB code: 9dba was solved by A.M.Hoffnagle, F.A.Tezcan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.07 / 2.20
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	72.26, 72.26, 56.83, 90, 90, 120
R / Rfree (%)	22.7 / 28.2

The binding sites of Cobalt atom in the Co-Bound Structure of Computationally Designed Homotrimer TET4 (pdb code 9dba). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total only one binding site of Cobalt was determined in the Co-Bound Structure of Computationally Designed Homotrimer TET4, PDB code: 9dba:

Cobalt binding site 1 out of 1 in the Co-Bound Structure of Computationally Designed Homotrimer TET4


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Co-Bound Structure of Computationally Designed Homotrimer TET4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Co201 b:86.3 occ:0.33 NE2 A:HIS38 2.1 77.5 1.0 O A:HOH324 2.3 49.1 0.3 CE1 A:HIS38 3.0 74.3 1.0 CD2 A:HIS38 3.2 70.3 1.0 ND1 A:HIS38 4.1 65.0 1.0 CG A:HIS38 4.2 63.9 1.0

A.M.Hoffnagle, S.Srisantitham, M.Neeley, C.Y.Tsai, F.A.Tezcan. A De Novo Designed Protein with Versatile Metal Binding and Tunable Hydrolytic Activity. Biochemistry 2025.
ISSN: ISSN 0006-2960
PubMed: 40700614
DOI: 10.1021/ACS.BIOCHEM.5C00259