Cobalt in PDB 1bk5: Karyopherin Alpha From Saccharomyces Cerevisiae

The structure of Karyopherin Alpha From Saccharomyces Cerevisiae, PDB code: 1bk5 was solved by E.Conti, M.Uy, L.Leighton, G.Blobel, J.Kuriyan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.50 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	157.980, 74.140, 84.050, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 27.6

The binding sites of Cobalt atom in the Karyopherin Alpha From Saccharomyces Cerevisiae (pdb code 1bk5). This binding sites where shown within 5.0 Angstroms radius around Cobalt atom.
In total 2 binding sites of Cobalt where determined in the Karyopherin Alpha From Saccharomyces Cerevisiae, PDB code: 1bk5:
Jump to Cobalt binding site number: 1; 2;

Cobalt binding site 1 out of 2 in the Karyopherin Alpha From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 1 of Karyopherin Alpha From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Co1 b:48.2 occ:1.00 OE2 B:GLU506 3.5 55.1 0.0 O A:GLY161 4.0 39.0 1.0 O A:ASN199 4.1 33.6 1.0 OG1 A:THR166 4.2 32.2 1.0 OD1 A:ASP203 4.2 41.7 1.0 CD B:GLU506 4.5 55.0 0.0 OD1 A:ASN199 4.5 38.1 1.0 CA A:ASP203 4.6 34.8 1.0 OE1 B:GLU506 4.6 55.1 0.0 CB A:ASP203 4.8 37.2 1.0 N A:SER163 4.9 40.0 1.0 N A:ASP203 4.9 34.6 1.0

Cobalt binding site 2 out of 2 in the Karyopherin Alpha From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Cobalt with other atoms in the Co binding site number 2 of Karyopherin Alpha From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Co1 b:53.5 occ:1.00 OD1 B:ASP203 3.7 54.7 1.0 O B:HOH556 3.9 61.5 1.0 O B:GLY161 3.9 47.6 1.0 O B:ASN199 4.2 43.8 1.0 OG1 B:THR166 4.2 49.7 1.0 OE1 A:GLU506 4.3 68.0 1.0 CA B:ASP203 4.5 47.8 1.0 OD1 B:ASN199 4.6 42.5 1.0 CG B:ASP203 4.6 52.7 1.0 CB B:ASP203 4.6 50.0 1.0 N B:SER163 4.8 53.0 1.0 CA B:SER163 4.8 54.1 1.0 C B:THR162 4.9 53.0 1.0 N B:ASP203 4.9 47.9 1.0

E.Conti, M.Uy, L.Leighton, G.Blobel, J.Kuriyan. Crystallographic Analysis of the Recognition of A Nuclear Localization Signal By the Nuclear Import Factor Karyopherin Alpha. Cell(Cambridge,Mass.) V. 94 193 1998.
ISSN: ISSN 0092-8674
PubMed: 9695948
DOI: 10.1016/S0092-8674(00)81419-1